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68 Cards in this Set
- Front
- Back
mRNA |
Messenger RNA: carries information from DNA to ribosome. |
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tRNA |
Transfer RNA: Binds with specific amino acids, carry amino acids to ribosome. |
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rRNA |
Ribosomal RNA: component of ribosomes, enzymatic function. |
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What is in mRNA? |
Has codons to be translated by ribosome. |
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What does tRNA do? |
adaptive molecule: 1. has to read codons. 2. carry appropriate amino acids. |
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What happens during Initiation of mRNA Synthesis? |
Begins at promoter sequence. (TATA Box in eukaryotes) DNA binds to protein. DNA unwinds. Enters at active site, unwound and base pairs are added to RNA strand. |
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What happens during Elongation of mRNA synthesis? |
Rudder and zipper keep moving down the DNA strand, locking RNA molecule into place. Complementary base pairs are made, antiparallel. DNA goes out channel of protein and rewinds itself. mRNA comes out of protein as a single strand. |
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What happens during Termination on mRNA synthesis? |
Happens when terminator sequence in reached. Eukaryotes: polyadenylation signal (AAAAAAAA) |
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What is primary transcript? |
product of transcription. |
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What does RNA processing produce? |
More mature RNA.
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What are three ways to make RNA more mature? |
1. Adding of 5' cap- 2-methylguanasine 2. Removal of introns (splicing) 3. Adding of 3' poly A tail |
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What happens in splicing? |
snRNPs find introns and remove them, exons then joined together. |
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What is alternative splicing? |
creating a unique combo of exons so that 1 gene can code for more than one protein.
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How many different types of tRNA are there? |
40!!!!!!!!!! |
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What enzyme attaches amino acids to tRNA? |
aminoacyl tRNA synthase |
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What are the two parts of the ribosome called? |
Large subunit and small subunit. |
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What is the A site in Translation? |
aminoacyl tRNA site- loaded tRNA enters here. |
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What is the P site in Translation? |
Peptiolyl site |
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What is the E site in Translation? |
E site- empty tRNA leave through the E site. |
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What happens during Initiation in Translation? |
Starts with small subunit of ribosome. Proteins called inititation factors. mRNA binds to small subunit in ribosome. -initiator aminoacyl tRNA binds to start codon, creates complementary base pairs with codon. large subunit is then added to the process. |
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What happens during Elongation in Translation? |
peptide bond formation tRNA enters at A site Addition of anticodon puts the amino acids very close to each other peptide bond forms between the two amino acids Translocation- ribosome moves codon down, tRNA shifts down as well. |
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What happens during Termination in Translation? |
stop codon Protein release factor binds to stop codon empty tRNA is released. synthesis stops
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What is a cell? |
basic structural and functional unit of life. |
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Tissue |
group of cells that function as a unit. |
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Organs |
groups of tissue organized into a unit. |
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Organ system |
groups of organs and tissues that work together to perform a function. |
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Epithelial tissue |
continuous layer of cells cover body surfaces line body cavities endothelium- cells that line blood vessels form glands |
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Function of epithelial tissue |
1. protection 2. absorption 3. secretion (glands) NOT EXCRETION 4. sensation |
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Two sides to epithelial tissue |
apical side (inside) basolateral side (outside)- connects to other tissues. |
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Connective Tissue |
relatively few cells intercellular substance (matrix)
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Four types of connective tissue |
1. Loose: soft, extracellular matrix, provides padding 2. Dense: fibrous, extracellular matrix, provides connections 3. Supporting: form, extracellular matrix, functions in support and protection 4. Fluid: liquid, extracellular matrix, functions in transport |
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Nervous tissue |
cells: neurons- transmit electrical signals glial cells- supporting cells
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Muscle Tissue |
moves body pumps the heart moving and mixing of food in digestive system |
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Three types of muscle tissue |
Skeletal- attaches to bones Cardiac- walls of the heart Smooth- walls of digestive organs and blood vessels |
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Homeostasis |
stability in chemical and physical conditions in n organism's body. |
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Internal conditions maintained by homeostasis |
temperature blood pressure blood pH blood glucose |
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What are three parts of the Regulatory system? |
Sensor- sense the environment Integrator- evaluates information, decids on action Effector- carries out response ex. hormonal regulation of blood glucose |
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Electrolyte |
solute that ionizes in water, contribute to electrical signals Ex. Na+, K+, Ca2+, Cl- |
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osmolarity |
concentration of dissolved substances in a solution |
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isosmotic |
equal solute concentration |
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hyperosmotic |
higher solute concentration |
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hyposmotic |
lower solute concentration |
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Passive transport |
based on concentration gradient Ex. direct diffusion channel proteins carrier proteins |
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active transport |
requires an energy source to move molecules against a gradient |
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Primary and secondary active transport |
1. Sodium potassium pump- driven by energy from ATP 2. symporters, antiporter- driven by energy from gradient |
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Cotransport |
Uses energy stored in an electrochemical gradient to transport a different solute against its concentration gradient. |
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Symport |
solutes move in the same direction |
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antiport |
solutes move in the opposite direction |
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The nephron |
functional unit of the kidney |
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Neprhon functions |
1. filtration- size selective 2. reabsorption- things added back into the blood 3. secretion 4. excretion- urine! |
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filtration |
blood is filtered from glomerulus capillaries into Bowman's capsule |
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reabsorption |
products being added back into the blood
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secretion |
continual secretion of substances into the tubular fluid, enhances the kidneys ability to eliminate certain wastes and toxins. |
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excretion |
what goes into the urine, releasing of urine into the toilet!!! |
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Composition of filtrate |
water nutrients (glucose, amino acids) wastes (urea, drugs) electrolytes (Na+, K+, Cl-, etc) |
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Ingesting |
taking in food |
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Digestion |
breakdown of food into monomers |
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Absorption |
uptake of nutrients |
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Elimination |
disposal of wastes |
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Nutrients |
proteins carbohydrates fats |
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Essential nutrients |
some amino acids vitamins minerals electrolytes |
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Digestion |
chewing increases surface area saliva lubricates food enzymes begin to digest food- salivary amylase, lingual lipase (fat digestion)
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Esophagus |
muscle constricts, muscle moves food muscle contraction moves in waves down esophagus, pushing food below to stomach |
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Stomach |
muscle contractions mix contents low pH due to HCl Pepsin digests proteins |
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Small intestine |
proteins, carbs and lipids are broken down by pancreas monomer are transported into epithelial cells transport is selective and active |
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Large Intestine |
solid waste compacted into feces additional water absorption occurs normal microbiota digest cellulose and produce nutrients like Vitamin K |
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appendix |
contains immune tissue harbors symbiotic bacteria |
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anus |
waster is eliminated through the anus |