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65 Cards in this Set
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- Back
Upper Respiratory Tract Infections (URIs): 7 |
Viral pharyngitis Bacterial pharyngitis The common cold Viral tonsillitis Bacterial tonsillitis Rhinitis Sinusitis |
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Respiratory Syncytial Virus (RSV) |
supportive tx |
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Bronchiolitis. viral or bacterial? |
mostly viral |
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Croup: most common age/gender, upper or lower airway? |
young boys, upper airway |
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Pertussis: age at risk and prevention? |
"whooping cough" kids prevent: immunizations |
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Cystic fibrosis |
cf |
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Asthma |
step 1-6. questions based on severity. cannot dx the level during an acute exacerbation. will get a scenario of a pt and have to tell severity and what will prescribe. |
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Pneumonia: atypical: who's at risk? CAP: who's at risk and tx: |
atypical: young adults get this CAP: children from : virus: RSV children Bacterial - adults: 20-60% Strep pnm 10-15% H flu B lactam PLUS Macrolid (azithromycin) or Fluoroquinolone |
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The common cold: |
viral URI sneezing, malaise, watery nasal discharge, mild sore throat, +/- fever tx: NO antibiotic. tx pain and fever |
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The FDA recommendations for <6yo cold/cough meds |
Recommended that oral OTC cough and cold ingredients should no longer be available for children under 6 years of age |
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Most frequent cause of hospitalizations of infants? |
bronchiolitis |
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Causes of Bronchiolitis |
predominately viral RSV >50% of cases |
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pathophysiology of bronchiolitis: |
Bronchiolar obstruction due to edema Accumulation of mucus and cellular debris Invasion of the smaller bronchial tubes by virus Ball valve respiratory obstruction leading to air trapping and overinflation |
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RSV symptoms |
Pharyngitis, +/- fever, occasionally otitis media, coryza, bronchitis/bronchiolitis, pneumonia |
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Croup caused from and s/s |
viruses laryngotracheobronchitis symptoms worse at night inspiratory stridor |
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Pertussis: organism and s/s |
"whooping" cough organism: bordatella pertussis cough starts as a dry intermittent hack post tussive emesis is common |
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Pertussis tx: |
erythromycin |
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Cystic Fibrosis |
multisystem genetic disorder: GI, COPD, exocrine dysfunction, malabsorbtion of nutrients by pancreas |
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PNM: 3 types |
Lobar Interstitial Bronchopneumonia |
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Lobar PNM: |
involves depositions in the alveolar space that result in consolidation all or part of a lobe of the lung |
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Interstitial PNM: |
cellular infiltrates attack the interstitium, which makes up the walls of the alveoli, the alveolar sacs and ducts, and the bronchioles (typical of acute viral infections) |
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Bronchopneumonia PNM: |
inflammation is centered in the bronchioles and is characterized by mucopurulent exudate->patchy consolidation involves more than 1 lobe |
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causes of PNM: |
viral or bacterial RSV, flu, adenovirus, parainfluenza |
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S/S PNM: |
high fever, cough/wheezing/stridor, restlessness, chills, nasal flaring, grunting, retractions, tachypnea, abd pain |
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Viral PNM tx: |
antipyretics, hydration, rest can use amoxacillin |
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Asthma defined as: |
an immunohistopathologic response |
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asthma described: |
This response produces shedding of airway epithelium, edema, mast cell activation, and inflammatory infiltration by eosinophils, lymphocytes, and neutrophils The result: airway inflammation, acute bronchospasm, airway edema, mucus plugs |
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dx asthma: 5 years or older |
Spirometry: gold standard An increase in FEV1 of ≥12 percent from baseline or An increase ≥10 percent of predicted FEV1 after inhalation of a short-acting bronchodilator |
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Classifications of Asthma |
Step 1: Intermittent Step 2: Mild persistent Step 3: Moderate Persistent Step 4: Severe Persistent |
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Intermittent: |
Symptoms ≤ 2× per week Nighttime symptoms ≤ 2× per month No interference with normal activity FEV1/FVC normal |
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Mild persistent |
Symptoms >2 days/ week but not daily Nighttime asthma symptoms 3-4× per month Minor limitation to activity FEV1/FVC normal |
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Moderate persistant |
Daily symptoms Nighttime asthma symptoms >1× per week but not nightly FEV1/FVC reduced 5% |
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Severe persistant |
Symptoms throughout the day Often 7×/week night time wakening FEV1/FVC reduced >5% |
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management of asthma |
for tx: tx at the level they present to rapidly control symptoms and then taper down to achieve control of symptoms. |
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what is the most common cause of childhood hospitalization? |
asthma |
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Pharmacological tx for asthma, quick-relief meds: |
short acting beta 2 agonist (SABA): albuterol, levalbuterol Inhaled anticholinergics: atrovent systemic corticosteroids: mythylprednisone/prednisone |
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Pharmacological Therapy: Long-Term Control Medications |
corticosterids inhaled: flovent long acting inhaled beta 2 agonist: LABA |
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do not use ___ in acute exacerbations |
long acting B2 antagonists |
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IH vs IV |
Of note, studies suggest that if patients do not respond to inhaled they won't respond to parenteral Epinephrine 1:1000 (1mg.ml) – 0.3-0.5 q 20 min SQ × 3 doses Terbutaline (1mg/ml) – 0.25mg q 20 min SQ × 3 doses |
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Role of anticholinergics |
Meta-analysis reviewed 10 studies- modest improvement in PFT’s noted and significant decrease in hospitalization rates noted |
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recommendations for systemic corticosteroids: |
Recommended for most patients. Early treatment with corticosteroids dramatically reduces need for hospitalization and probably reduces the likelihood of death from acute asthma. Recommended if not responding to β2 agonists |
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Magnesium |
Intravenous has bronchodilator activity in acute asthma Magnesium 2 GMs over 20 minutes Safe Contraindicated in renal insufficiency |
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Not recommended for asthma tx: |
mucolytics, abx, |
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predictor of hospitalization: |
FEV1 and s/s scores 1 hour after initial tx improve ability to predict need for hospitalization |
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Community Acquired PNM |
Associated with at least 2 symptoms of acute infection Fever or Hypothermia Diaphoresis Shaking chills Cough with or without sputum production, or change in the color of sputum in a patient with chronic cough, pleuritic chest pain or dyspnea |
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Who's at risk for CAP? |
<2 yo and >65 yo bc decreased immunity |
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CAP : s/s |
decreased appetite, cough, fever, dypsnea, elderly who are around young children |
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CAP caused by what organisms: adults children |
20-60% Strep pnm 10-15% H flu leading cause in children: RSV |
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Strep pnm usually causes what type of pnm? |
lobular |
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s/s pnm in elderly: |
mental status changes or increased resp rate |
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if have CAP and pregnant, tx with: |
B lactam PLUS Macrolid Do not use fluoroquinolones in pregnancy if preg don't use fluoro or you may hurt the baby |
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CAP and not pregnant, tx: |
B lactam PLUS Macrolid (azithromycin) or Fluoroquinolone |
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CURB-65: 1 point for everything they have: if confusion, 1 point. admission consideration criteria |
Confusion (new disorientation to person, time and place) Elevation of Blood Urea Nitrogen (BUN) Level above 7mmol/L(urea) or 20mg% BUN Respiratory rate over 30 breaths/min Low BP ( Age >65 years 1 point for each criteria-consider admission for score >2 |
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Atypical Pneumonia pathogen |
Atypical Pathogen: not a bacteria. not a cocci or bacillus. They are obligate intracellular organisms that need to live inside our cells. |
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Atypical Pneumonia s/s |
No evidence of lung consolidation on physical examination or radiographic examination. Radiographic findings are patchy infiltrate if anything. known as walking mans pneumonia More diffuse illness. low grade fever, cough, upper resp symptoms. |
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atypical pnm types: |
Mycoplasma Pneumoniae Chlamydophila Pneumoniae Legionella pnm |
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Legionella Pneumphila |
pnm with hyponatremia, bradycardia |
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What is the definition of Hospital Acquired Pneumonia (HAP)? |
occurs 48 hours or more after admission. There was no evidence of incubating pneumonia at the time of admission. |
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What causative pathogens do you need to consider for a patient with HAP? |
Aerobic gram-negative bacilli P. aeurginosa, E. coli, Klebsiella pneumoniae, Acinetobacter spp. Gram positive cocci Staphylococcus aures, MRSA (MRSA can be hospital acquired or community acquired.. which are different resistance) Oral bacteria Streptococcus virdins |
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Early and Late Onset of HAP or VAP prognosis |
Early onset of HAP or VAP (Ventilator Acquired PNA) Occurs in first 4 days of hospitalization Late onset HAP or VAP Poor prognosis Higher mortality rate |
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HAP tx for early onset and no known risk factors for MDRP |
Ceftriaxone Levofloxacin ampicillin Ertapenem |
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Late onset or risk for MDRP: Pathogen and tx |
acinetobacter tx: cefepime, meropenem, zosyn |
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Peak incidence of bronchiolitis |
6 months |
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PMN incidence increases w age? |
true |
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tx for CAP? |
Azythromycin |