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64 Cards in this Set

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What does the APGAR score assess?

Assessment of newborn vital signs following labor, via a 10-point scale evaluated at 1 minute and 5 minutes
- A: Appearance
- P: Pulse
- G: Grimace
- A: Activity
- R: Respiration
What do the APGAR scores indicate?
- ≥ 7 = good
- 4-6 = assist and stimulate
- <4 = resuscitate

If score remains <4 at later time points, there is increased risk the child will develop long-term neurological damage
What is the definition of a low birth weight infant?
< 2500 g
What can cause low birth weight (<2500g)?
- Prematurity
- Intrauterine growth retardation
What problems are associated with a low birth weight (<2500g)?
- ↑ Risk of SIDS
- ↑ Overall mortality
- Impaired thermoregulation and immune function
- Hypoglycemia
- Polycythemia
- Impaired neurocognitive / emotional development
What are the complications of a low birth weight (<2500g)?
- Infections
- Respiratory distress syndrome
- Necrotizing entercolitis
- Intraventricular hemorrhage
- Persistent fetal circulation
What are the motor, social, and verbal/cognitive milestones from birth to 3 months?
- Motor: rooting reflex, holds head up, Moro reflex disappears
- Social: social smile
- Verbal/cognitive: orients and responds to voice
What are the motor, social, and verbal/cognitive milestones from 7-9 months?
- Motor: sits alone, crawls, transfers toys from hand to hand
- Social: stranger anxiety
- Verbal/cognitive: responds to name and simple instructions, uses gestures, plays peek-a-boo
What are the motor, social, and verbal/cognitive milestones from 12-15 months?
- Motor: walks, Babinski sign disappears
- Social: separation anxiety
- Verbal/cognitive: few words
What are the motor, social, and verbal/cognitive milestones from 12-24 months?
- Motor: climbs stairs, stacks 3 blocks at 1 yr, 6 blocks at 2 yr
- Social: rapprochement (moves away from and then returns to mother)
- Verbal/cognitive: 200 words and 2-word phrases at age 2
What are the motor, social, and verbal/cognitive milestones from 24-36 months?
- Motor: feeds self with fork and spoon, kicks ball
- Social: core gender identity, parallel play
- Verbal/cognitive: toilet training ("pee at 3")
What are the motor, social, and verbal/cognitive milestones from 3 years?
- Motor: Rides tricycle (3-cycle at age 3) and copies lines or circle drawings
- Social: comfortably spends part of day away from mother
- Verbal/cognitive: 900 words and complete sentences
What are the motor, social, and verbal/cognitive milestones from 4 years?
- Motor: use buttons and zippers, grooms self (brushes teeth), hops on 1 foot, makes simple drawings (stick figures)
- Social: cooperative play, imaginary friends
- Verbal/cognitive: can tell detailed stories and use prepositions
What are the sexual changes that occur in elderly men?
- Slower erection and ejaculation
- Longer refractory period
What are the sexual changes that occur in elderly women?
Vaginal shortening, thinning and dryness
What are the sleep changes that occur in the elderly?
- ↓ REM and slow wave sleep
- ↑ Latency and awakenings
What age group has the highest suicide rate?
Men 65-74 years of age have the highest suicide rate in the US
What physiologic changes occur in the elderly?
- ↓ Vision, hearing, immune response, bladder control
- ↓ Renal, pulmonary, GI function
- ↓ Muscle mass and ↑ Fat
- Presbycusis: high-frequency hearing loss d/t destruction of hair cells at the cochlear base (preserved low-frequency hearing at apex)
What are the characteristics of normal grief and bereavement?
- Shock
- Denial
- Guilt
- Somatic symptoms
- May experience delusions

- Lasts up to 1 year
What are the characteristics of pathologic grief and bereavement?
- Excessively intense grief
- Grief that is delayed, inhibited, or denied
- May experience depressive symptoms, delusions, and hallucinations

- Prolonged grief lasting >2-6 months
What are the types of sexual DESIRE disorders?
- Hypoactive sexual desire
- Sexual aversion
What are the types of sexual AROUSAL disorders?
Erectile Dysfunction
What are the types of ORGASMIC disorders?
- Anorgasmia
- Premature ejaculation
What are the types of sexual PAIN disorders?
- Dyspareunia
- Vaginismus
What does a differential diagnosis for sexual dysfunction include?
- Drugs (eg, anti-hypertensives, neuroleptics, SSRIs, ethanol)
- Diseases (eg, depression, diabetes)
- Psychological (eg, performance anxiety)
What drugs can cause sexual dysfunction?
- Anti-hypertensives
- Neuroleptics
- SSRIs
- Ethanol
What diseases can cause sexual dysfunction?
- Depression
- Diabetes
What psychological state can cause sexual dysfunction?
Performance anxiety
How do you calculate BMI?
BMI = weight in kg / (height in meters)^2
How do you classify the BMI scores?
< 18.5 is underweight
18.5 - 24.9 is normal weight
25.0 - 29.9 is overweight
> 30.0 obesity
> 35.0 severe obesity
> 40.0 morbid obesity
> 45.0 super obesity
What are the stages of sleep?
- Awake (eyes open)
- Awake (eyes closed)
- Stage N1
- Stage N2
- Stage N3
- REM
How do you remember the EEG waveforms that correspond to the progressive stages of sleep?
At night, BATS Drink Blood
- β (Beta) - Awake (eyes open)
- α (Alpha) - Awake (eyes closed)
- 𝚹 (Theta) - Stage N1
- Sleep spindles and K complexes - Stage N2
- δ (Delta) - Stage N3
- β (Beta) - REM
What is happening during the awake (eyes open) stage? EEG waveform?
- Alert, active mental concentration
- β (highest frequency, lowest amplitude)

At night, (B)ATS Drink Blood
- Alert, active mental concentration
- β (highest frequency, lowest amplitude)

At night, (B)ATS Drink Blood
What is happening during the awake (eyes closed) stage? EEG waveform?
α waves

At night, B(A)TS Drink Blood
α waves

At night, B(A)TS Drink Blood
What is happening during the N1 stage? EEG waveform? Percent of total sleep time in young adults?
- Light sleep
- Theta waves
- 5% of total sleep

At night, BA(T)S Drink Blood
- Light sleep
- Theta waves
- 5% of total sleep

At night, BA(T)S Drink Blood
What is happening during the N2 stage? EEG waveform? Percent of total sleep time in young adults?
- Deeper sleep, bruxism (teeth grinding)
- Sleep spindles and K complexes
- 45% of total sleep

At night, BAT(S) Drink Blood
- Deeper sleep, bruxism (teeth grinding)
- Sleep spindles and K complexes
- 45% of total sleep

At night, BAT(S) Drink Blood
What is happening during the N3 stage? EEG waveform? Percent of total sleep time in young adults?
- Deepest, non-REM sleep (slow-wave sleep)
- Sleepwalking, night terrors, bed-wetting
- Delta waves (lowest frequency, highest amplitude)
- 25% of total sleep

At night, BATS (D)rink Blood
- Deepest, non-REM sleep (slow-wave sleep)
- Sleepwalking, night terrors, bed-wetting
- Delta waves (lowest frequency, highest amplitude)
- 25% of total sleep

At night, BATS (D)rink Blood
What is happening during the REM stage? EEG waveform? Percent of total sleep time in young adults?
- Dreaming, loss of motor tone
- Possibly a memory processing function
- Erections
- ↑ Brain O2 use
- Beta waves
- 25% of total sleep

At night, BATS Drink (B)lood
- Dreaming, loss of motor tone
- Possibly a memory processing function
- Erections
- ↑ Brain O2 use
- Beta waves
- 25% of total sleep

At night, BATS Drink (B)lood
What percentage of the total sleep does each of the sleep stages take?
- Stage N1 (5%)
- Stage N2 (45%)
- Stage N3 (25%)
- REM (25%)
What brain structure is key to initiating sleep?
Serotonergic predominance in the raphe nucleus
How do you treat sleep enuresis (bed-wetting)? Mechanism?
Oral desmopressin acetate (DDAVP)
- Mimics vasopressin (ADH)
- Preferred over imipramine because fewer side effects
Which drugs affect the quality of sleep? How?
Alcohol, benzodiazepines, and barbiturates:
- Reduced REM and delta (N3) sleep
How do you treat night terrors and sleep-walking?
Benzodiazepines
How often does REM sleep occur? How long does it last?
- Occurs every 90 minutes
- Increases in duration throughout the night
- 25% of the total sleep time
What neurotransmitters are involved in REM sleep?
- ACh is the principal NT in REM sleep
- NE reduces REM sleep
What are the findings of REM sleep?
- ↑ and variable pulse and BP
- Extraocular movements during REM sleep d/t hyperactivity of PPRF (paramedian pontine reticular formation / conjugate gaze center)
- Penile/clitoral tumescence (swelling)
- Paradoxical sleep (REM sleep has the same EEG pattern as wakefulness
How can you remember the changes that occur during REM sleep?
REM sleep is like sex:
- ↑ Pulse
- Penile / clitoral tumescence (swelling)
- ↓ Frequency with age
What causes the extraocular movements during REM sleep?
Hyperactivity of PPRF (paramedian pontine reticular formation / conjugate gaze center)
What are the sleep patterns of depressed patients?
- ↓ Slow-wave sleep
- ↓ REM latency
- ↑ REM early in sleep cycle
- ↑ Total REM sleep
- Repeated nighttime awakenings
- Early-morning awakening (important screening question)
What is narcolepsy?
- Disordered regulation of sleep-wake cycles
- Excessive daytime sleepiness
When can hallucinations occur in patients with narcolepsy?
- Just before sleep (hypnagogic)
- Just before awakening (hypnapompic)
What happens during the sleep cycle in a patient with narcolepsy?
Patient starts off with REM sleep
What symptoms do some patients with Narcolepsy experience?
- Hypnagogic (just before sleep) or hypnopompic (just before awakening) hallucinations
- Cataplexy (loss of all muscle tone following a strong emotional stimulus)
How do you treat narcolepsy?
- Daytime stimulants (amphetamines, modafinil)
- Nighttime sodium oxybate (GHB)
What brain structure drives the Circadian Rhythm?
Suprachiasmatic Nucleus (SCN) of Hypothalamus
- Controls ACTH, prolactin, melatonin, and nocturnal NE release
- SCN → NE release → Pineal Gland → Melatonin
- SCN is regulated by environment (eg, light)
What characterizes sleep terror disorder?
- Periods of terror with screaming in the middle of the night
- Occurs during slow wave sleep
- Most common in children
- Occurs during non-REM sleep (no memory of arousal)
- Triggers may include emotional stress during previous day, fever, or lack of sleep
- Usually self-limited
What characterizes nightmares?
Occurs during REM sleep (memory of a scary dream)
What are the common causes of death (US) for patients < 1 year old?
1. Congenital malformations
2. Preterm birth
3. SIDS
1. Congenital malformations
2. Preterm birth
3. SIDS
What are the common causes of death (US) for patients 1-14 years old?
1. Unintentional injury
2. Cancer
3. Homicide
1. Unintentional injury
2. Cancer
3. Homicide
What are the common causes of death (US) for patients 15-24 years old?
1. Unintentional injury
2. Homicide
3. Suicide
1. Unintentional injury
2. Homicide
3. Suicide
What are the common causes of death (US) for patients 25-34 years old?
1. Unintentional injury
2. Suicide
3. Homicide
1. Unintentional injury
2. Suicide
3. Homicide
What are the common causes of death (US) for patients 35-44 years old?
1. Unintentional injury
2. Cancer
3. Heart Disease
1. Unintentional injury
2. Cancer
3. Heart Disease
What are the common causes of death (US) for patients 45-64 years old?
1. Cancer
2. Heart disease
3. Unintentional injury
1. Cancer
2. Heart disease
3. Unintentional injury
What are the common causes of death (US) for patients 65+ years old?
1. Heart disease
2. Cancer
3. Chronic respiratory disease
1. Heart disease
2. Cancer
3. Chronic respiratory disease