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50 Cards in this Set

  • Front
  • Back

Adverse symptoms of steroids

Abd pain and tar stools

Cox enzymes are also known as what?

PGH2 prostaglandins

Ibuprofen is reversible or non reversible inhibitor of cox pathway?

Reversible

Is aspirin reversible or non reversible?

Non

Ibuprofen is selective or non selective?

Non- cox 1 causes the GI effects

Cox 2 does what?

Inhibits pains and inflammation

Antipyretic effects are actions from what?

Hypothalamus

Metformin

Inhibits glucogenisis


Increases insulin in muscles and tissues after meals


Triglycerides and cholesterol

Gliptin increases what?

Incretin

GLP is sucreated from?

L cells

GLP slows what?

Gastric emptying

GLP increases or decreases glucose?

Decreases

GLP works in what cells?

Alpha

Exenatide

Like GLP- regulates glucose and insulin secretion

Alpha glycosides dose and when to give?

50-100 with first bite of food

TZD side wffects

Water retention


Bladder cancer


Bone fractures

Insulin peaks

1,3,4, none

Insulin duration

5,10, 12-24, 24

Adverse effects of levothyroxine

Tachycardia, angina I’m elderly

PTU side effects

Fatal granulocytopenia

First sign of granulocytopenia

Fever and sore throat

Vasculitis is a side effect of what med?

PTU

Aplastic anemia is a side effect of what meds?

PTU

Does PTU inhibit iodine?

No, it converts t4 to t3

What is the difference with PTU and methimazole?

PTU works on thyroid and peripheral and methimazole only works in thyroid

What does methimazole inhibit?

Thyroperoxidase

What cardiac med is most likely going to effect the kidneys?

ACE

What is an effective cardiac med?

Ramipril

What are involved in the pacemaker signals?

Calcium channels

What are the classes of calcium channel blockers?

Dihydropyridines


Phenylalanine


Benzothiazepine

Dihydropyridines exsamples

Nifedipine and nicardipine-vasodialte smooth muscles

Phenylalanine

Verapamil- effects heart: negative inotrophic and chronotrophic

Benzothiazepine exsample

Diltiazem- combined effect of other two

Reflex tachycardia can be a problems with ischemic patients because??

Increased o2 demands

Amlodipine is what kind of CCB?

Dihydropyridine

What’s contradicted in amlodipine?

Grapefruit juice

Statins block what pathway?

Hmg- coa

What happens when the liver can no longer produce cholesterol?

Levels will fall

Fibric acid treat what?

Triglycerides

Do not use fibrates in patients with what?

Low HDL

Do not use fibrates in patients with what?

Low HDL

Acid sequestrants

Cholestyramine (cholybar, Olestyl)

Do not use fibrates in patients with what?

Low HDL

Acid sequestrants

Cholestyramine (cholybar, Olestyl)

Bile acids are excreted how?

In stool

If reduced ejection fraction then use what?

Aldosterone in addition to AcE and betas

Procanimide produce what after 6mths

Antibiodies

Exsample of sodium glucose co-transporter

Invonka

Exenatide (byetta)

1hr prior to meal sub q

Tricor does what?

Decreases LDL and triglycerides and increases HDL