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24 Cards in this Set

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What are resident microbes?

Microbes that reside in the body.

What place in the body has the most resident microbes?

The large intestines

How do most microbes get into the human body?

Via the respiratory tract

Name the microbes that engage in mutual or commensal associations.

Normal (resident) flora, indigenous flora, microflora, microbiota, and commensals

What is an Infection?

A condition in which microbes penetrate hostcell, invade sterile tissues and multiply.

What are microbes considered when there is an Infection?

Infectious agent or pathogen

Macrophages

Attacks to a microbe and presents the microbe to the immune system thus the process is called APC (antigen presenting cell)

Resident microbes

Able to avoid the unwanted attention of the body's defenses (Marcophages) and become established.

Endogenous infection

Occur when normal flora is introduced to a site that was previously sterile. Once was nonpathogenic was become immunocompromised and now is pathogenic.

Exogenous infection

True infection; Contact from the outside environment; ie measles or rabies

Infectious dose

The minimum # of microbes required for there to be an infection.

2 groups of pathogens

1. True pathogens


2. Opportunistic pathogens

What does the severity of the disease depend on?

Virulence of pathogen

Virulence factor

Structure that enables the microbe invade and cause a disease.

True pathogens

Can cause diseases in health people with normal immune defenses.

What kind of microbes have greater virulences?

Small microbes

The lack of what will not result in an infection.

Infectious dose (ID)

Pathogens

Parasitic microbes that has a harmful relationship with a host

What are examples of microbes with small IDs?

Measles, Hepatitis

Adhesion

Attachment to a surface. Gains a stable foothold at the portal of entry.

What does the slime layer do?

Make phagocytosis difficult

Virulence

The ^ rate @ which viruses are replicating = ^ virulence

Exoenzymes

Dissolve outside cells and penetrate through or btw cells

Toxigenicity

Capacity to produce toxins at the multiplication site