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24 Cards in this Set
- Front
- Back
What are resident microbes? |
Microbes that reside in the body. |
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What place in the body has the most resident microbes? |
The large intestines |
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How do most microbes get into the human body? |
Via the respiratory tract |
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Name the microbes that engage in mutual or commensal associations. |
Normal (resident) flora, indigenous flora, microflora, microbiota, and commensals |
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What is an Infection? |
A condition in which microbes penetrate hostcell, invade sterile tissues and multiply. |
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What are microbes considered when there is an Infection? |
Infectious agent or pathogen |
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Macrophages |
Attacks to a microbe and presents the microbe to the immune system thus the process is called APC (antigen presenting cell) |
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Resident microbes |
Able to avoid the unwanted attention of the body's defenses (Marcophages) and become established. |
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Endogenous infection |
Occur when normal flora is introduced to a site that was previously sterile. Once was nonpathogenic was become immunocompromised and now is pathogenic. |
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Exogenous infection |
True infection; Contact from the outside environment; ie measles or rabies |
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Infectious dose |
The minimum # of microbes required for there to be an infection. |
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2 groups of pathogens |
1. True pathogens 2. Opportunistic pathogens |
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What does the severity of the disease depend on? |
Virulence of pathogen |
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Virulence factor |
Structure that enables the microbe invade and cause a disease. |
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True pathogens |
Can cause diseases in health people with normal immune defenses. |
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What kind of microbes have greater virulences? |
Small microbes |
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The lack of what will not result in an infection. |
Infectious dose (ID) |
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Pathogens |
Parasitic microbes that has a harmful relationship with a host |
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What are examples of microbes with small IDs? |
Measles, Hepatitis |
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Adhesion |
Attachment to a surface. Gains a stable foothold at the portal of entry. |
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What does the slime layer do? |
Make phagocytosis difficult |
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Virulence |
The ^ rate @ which viruses are replicating = ^ virulence |
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Exoenzymes |
Dissolve outside cells and penetrate through or btw cells |
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Toxigenicity |
Capacity to produce toxins at the multiplication site |