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31 Cards in this Set

  • Front
  • Back

Selective (differential) permeability

Plasma membrane is selective about what passes through it. Allows nutrients to enter cell but keeps out undesirable substances. Valuable cell proteins and other substances are kept within the cell, and excreta or wastes pass to the exterior.

Passive Processes

Concentration or pressure differences drive the movement

Active Processes

Cell provides energy (ATP) to power the transport process

Two types of Passive Processes

Diffusion
Filtration

Diffusion

Important transport process for every cell in the body

Filtration

Usually occurs only across capillary walls



Diffusion

When a concentration gradient (difference in concentration) exists, the movement of molecules from a region of their higher concentration to a region of their lower concentration

Simple diffusion

Unassisted diffusion of solutes (dissolved substances) through a selectively permeable membrane

Facilitated diffusion

Substances moving by a passive transport process from high to low concentration


Example: Glucose are transported across the plasma membrane with the assistance of a protein carrier molecule

Osmosis

Flow of water across a selectively permeable membrane down its concentration gradient

Filtration

- Passive process in which water and solutes are forced through a membrane by hydrostatic (fluid) pressure


- Not selective


- amount of filtrate (fluids and solutes) formed depends almost entirely on the pressure gradient (difference in pressure on the two sides of the membrane) and on the size of the membrane pores

Active Processes

- Whenever a cell uses the bond energy of ATP to move substances across its boundaries



Substances moved by active means

- May not be lipid soluble


- May be too large to pass through membrane channels


- May have to move against rather than with a concentration gradient

Two types of Active Processes

Active Transport


Vesicular Transport

Active Transport

- Requires carrier proteins that combine specifically with the transported substance


- Substances move against concentration or electrochemical gradients or both

Vesicular Transport

- Fluids containing large particles and macromolecules are transported across cellular membranes inside membranous sacs called vesicles

Vesicles

- Membranous sacs that transport fluids containing large particles and macromolecules across cellular membranes

Endocytosis

- Vesicular transport moving substances into the cell

Exocytosis

- Vesicular transport moving substances out of the cell


- Used for hormone secretion, neurotransmitter release, mucus secretion and ejection of wastes

3 Types of Endocytosis

Phagocytosis


Pinocytosis


Receptor-mediated Endocytosis

Phagocytosis

- "Cell Eating"


- Cell engulfs some relatively large or solid material (Ex: clump of bacteria, cell debris,


inanimate particles)



Pinocytosis

- "Cell drinking"


- Also called Fluid-phase "endocytosis"


- Cell "gulps" a drop of extracellular fluid containing dissolved molecules


- Routine activity of most cells



Secretory Vesicle

- Protein coated vesicle that transports substances within the cell

Red and white blood cells. Isotonic Solution.


Cells retain their normal size and shape.

Red and white blood cells. Hypertonic Solution. Cells lose water by osmosis and go through crenation.

Red and white blood cells. Hypotonic Solution. Cells take on water by osmosis and swell to burst. Hemolysis, or lysis.

a. reflects the kinetic energy of molecules


d. is random and erratic

Molecular motion reflects the kinetic/potential energy of molecules and is ordered/random and predictable/erratic.

b. is lower in larger molecules


c. increases with increasing temperature

Speed of molecular movement is lower in smaller/larger molecules and increases with decreasing/increasing temperature

Size of pores. Solubility in the lipid portion of the membrane and/or presence of membrane “carriers” for the substance(s).

What single characteristic of the differentially permeable membranes used in the laboratory determines the substances that can pass through them? In addition to this characteristic, what other factors influence the passage of substances through living membranes?

Passive Transport

- account for the movement of fats and respiratory gases through the plasma membrane


- include osmosis, simple diffusion, and filtration


- use hydrostatic pressure or molecular energy as the driving force

Active Transport

- explain solute pumping, phagocytosis, and pinocytosis


- may occur against concentration and/or electrical gradients


- move ions, amino acids, and some sugars across the plasma membrane