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6 Cards in this Set
- Front
- Back
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List the steps of infection
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Encounter
Colonisation Penetration Spread Damage Resolution |
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How do pathogens encounter the host?
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Directly
Inhaled Ingested Implanted Transplacentally |
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How do pathogens colonise the host?
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Compete against natural flora
Skin, pH & antimicrobial's Resist local defence mechanisms Immune privileged site Forming a biofilm |
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How does a pathogen penetrate the host
Biofilm? |
Break in epithelial/mucosal layers
Intracellular bacteria UTI, respiratory Taken up by cells |
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How does the pathogen Spread in the host?
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Extension through the surrounding tissue
Veins and lymphatic vessels Active role movement Destruction of cells |
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What types of damage can a pathogen cause?
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Altered function
Host response Toxins Bulk effect |
