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199 Cards in this Set
- Front
- Back
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Through what is the specialized function of epithelial cells mediated?
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Structural modifications on the cell's surface
Internal modification which adapt cells to manufacture and sectete a product |
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For what are epithelial cells specialized?
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Absorption
Secretion Act as a barrier |
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Epithelial cells form cohesive sheets of cells called epithelia - function?
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Covering/lining for body surfaces (skin, gut and ducts)
Functional units of secretory glands (salivary tissue and liver) |
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3 Main cell groups according to shape?
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Squamous (flat plate-like)
Cuboidal (height and width similar. Central nuclei) Columnar (height 2-5 times greater than width. Nuclei basal and arranged in a orderd layer ) |
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Layering of cells
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Single layer - cells contact underlying extracellular matrix (stratified)
Several layers - only the bottom layer of cells is in contact with the extracellular matrix (stratified epithelium) Pseudostratified - epithelial cells that appear to be layered but are in contact with the extracellular matrix |
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Endothelium
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Flat epithelium lining blood vessels
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Endothelium
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Flat epithelium lining blood vessels
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Mesothelium
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Lining of the abdominal and plaural cavities
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Endothelium
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Flat epithelium lining blood vessels
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Mesothelium
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Lining of the abdominal and plaural cavities
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How is the structural integrity of epithelium maintained?
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Adhesion of the constituent cells, both to each other and to structural extracellular matrix
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Endothelium
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Flat epithelium lining blood vessels
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Mesothelium
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Lining of the abdominal and plaural cavities
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How is the structural integrity of epithelium maintained?
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Adhesion of the constituent cells, both to each other and to structural extracellular matrix
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Adhesions of constituent cells are mediated by..
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Cellmembrane proteins acting as specialized cell adhesion molecules
Specialized areas of cell membrane incorporated into cell junctions |
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3 Types of cell junctions
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Occluding junctions - link cells to form a impermeable (ondeurdringbaar) barrier
Anchoring junction - link cells to provide mechanical strenght Communicating junctions - allow movement of molecules between cells |
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Functions of occluding junctions
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Prevention of diffusion of molecules between adjacent cells, contributing to the barrier function of epithelial cells.
Prevention of lateral migration of spesialized cell membrane proteins. Delineating (outline) and maintaining specialized cell membrane domains. |
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Functions of occluding junctions
|
Prevention of diffusion of molecules between adjacent cells, contributing to the barrier function of epithelial cells.
Prevention of lateral migration of spesialized cell membrane proteins. Delineating (outline) and maintaining specialized cell membrane domains. |
|
|
By what is the occluding function performed
|
By intermembranous proteins which mediate the adhesion of adjacent cells.
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Functions of occluding junctions
|
Prevention of diffusion of molecules between adjacent cells, contributing to the barrier function of epithelial cells.
Prevention of lateral migration of spesialized cell membrane proteins. Delineating (outline) and maintaining specialized cell membrane domains. |
|
|
By what is the occluding function performed
|
By intermembranous proteins which mediate the adhesion of adjacent cells.
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What is occluding junction's other name?
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Tight junction
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What led to the name tight junction?
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Ultrastructurally an occluding junction is seen as a focal area of close apposition of adjacent cell membrane.
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|
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Functions of occluding junctions
|
Prevention of diffusion of molecules between adjacent cells, contributing to the barrier function of epithelial cells.
Prevention of lateral migration of spesialized cell membrane proteins. Delineating (outline) and maintaining specialized cell membrane domains. |
|
|
By what is the occluding function performed
|
By intermembranous proteins which mediate the adhesion of adjacent cells.
|
|
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What is occluding junction's other name?
|
Tight junction
|
|
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What led to the name tight junction?
|
Ultrastructurally an occluding junction is seen as a focal area of close apposition of adjacent cell membrane.
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Occluding junction's importance in active transport
|
Prevent back-diffusion of tranported substance.
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|
|
Functions of occluding junctions
|
Prevention of diffusion of molecules between adjacent cells, contributing to the barrier function of epithelial cells.
Prevention of lateral migration of spesialized cell membrane proteins. Delineating (outline) and maintaining specialized cell membrane domains. |
|
|
By what is the occluding function performed
|
By intermembranous proteins which mediate the adhesion of adjacent cells.
|
|
|
What is occluding junction's other name?
|
Tight junction
|
|
|
What led to the name tight junction?
|
Ultrastructurally an occluding junction is seen as a focal area of close apposition of adjacent cell membrane.
|
|
|
Occluding junction's importance in active transport
|
Prevent back-diffusion of tranported substance.
|
|
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Anchoring junctions
|
Provide mechanical stability to groups of epithelial cells so that they can function as a cohesive unit
|
|
|
Functions of occluding junctions
|
Prevention of diffusion of molecules between adjacent cells, contributing to the barrier function of epithelial cells.
Prevention of lateral migration of spesialized cell membrane proteins. Delineating (outline) and maintaining specialized cell membrane domains. |
|
|
By what is the occluding function performed
|
By intermembranous proteins which mediate the adhesion of adjacent cells.
|
|
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What is occluding junction's other name?
|
Tight junction
|
|
|
What led to the name tight junction?
|
Ultrastructurally an occluding junction is seen as a focal area of close apposition of adjacent cell membrane.
|
|
|
Occluding junction's importance in active transport
|
Prevent back-diffusion of tranported substance.
|
|
|
Anchoring junctions
|
Provide mechanical stability to groups of epithelial cells so that they can function as a cohesive unit
|
|
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Occludal junctions: intermembranous proteins that form these junctions are lines that stitch the membrane of adjacent cells together. Which protein is involved?
|
Occludin
Claudin |
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|
Functions of occluding junctions
|
Prevention of diffusion of molecules between adjacent cells, contributing to the barrier function of epithelial cells.
Prevention of lateral migration of spesialized cell membrane proteins. Delineating (outline) and maintaining specialized cell membrane domains. |
|
|
By what is the occluding function performed
|
By intermembranous proteins which mediate the adhesion of adjacent cells.
|
|
|
What is occluding junction's other name?
|
Tight junction
|
|
|
What led to the name tight junction?
|
Ultrastructurally an occluding junction is seen as a focal area of close apposition of adjacent cell membrane.
|
|
|
Occluding junction's importance in active transport
|
Prevent back-diffusion (claudin) of tranported substance.
|
|
|
Anchoring junctions
|
Provide mechanical stability to groups of epithelial cells so that they can function as a cohesive unit
|
|
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Occludal junctions: intermembranous proteins that form these junctions are lines that stitch the membrane of adjacent cells together. Which protein is involved?
|
Occludin
Claudin |
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Through what are cytoskeletal filaments of adjacent cells joint
|
Intracellular link proteins, they attach the filaments to tranmembrane link proteins.
|
|
|
Functions of occluding junctions
|
Prevention of diffusion of molecules between adjacent cells, contributing to the barrier function of epithelial cells.
Prevention of lateral migration of spesialized cell membrane proteins. Delineating (outline) and maintaining specialized cell membrane domains. |
|
|
By what is the occluding function performed
|
By intermembranous proteins which mediate the adhesion of adjacent cells.
|
|
|
What is occluding junction's other name?
|
Tight junction
|
|
|
What led to the name tight junction?
|
Ultrastructurally an occluding junction is seen as a focal area of close apposition of adjacent cell membrane.
|
|
|
Occluding junction's importance in active transport
|
Prevent back-diffusion (claudin) of tranported substance.
|
|
|
Anchoring junctions
|
Provide mechanical stability to groups of epithelial cells so that they can function as a cohesive unit
|
|
|
Occludal junctions: intermembranous proteins that form these junctions are lines that stitch the membrane of adjacent cells together. Which protein is involved?
|
Occludin
Claudin |
|
|
Through what are cytoskeletal filaments of adjacent cells joint
|
Intracellular link proteins, they attach the filaments to tranmembrane link proteins. These can interact with similar proteins on adjacent cells. These extracellular interactions may be mediated by additional extracellular proteins or ions such as Calcium ions.
|
|
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Cadherins
|
Protein that link extracellulary cytoskeletal filaments (link between adjacent cells using Calcium ions).
|
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Functions of occluding junctions
|
Prevention of diffusion of molecules between adjacent cells, contributing to the barrier function of epithelial cells.
Prevention of lateral migration of spesialized cell membrane proteins. Delineating (outline) and maintaining specialized cell membrane domains. |
|
|
By what is the occluding function performed
|
By intermembranous proteins which mediate the adhesion of adjacent cells.
|
|
|
What is occluding junction's other name?
|
Tight junction
|
|
|
What led to the name tight junction?
|
Ultrastructurally an occluding junction is seen as a focal area of close apposition of adjacent cell membrane.
|
|
|
Occluding junction's importance in active transport
|
Prevent back-diffusion (claudin) of tranported substance.
|
|
|
Anchoring junctions
|
Provide mechanical stability to groups of epithelial cells so that they can function as a cohesive unit
|
|
|
Occludal junctions: intermembranous proteins that form these junctions are lines that stitch the membrane of adjacent cells together. Which protein is involved?
|
Occludin
Claudin |
|
|
Through what are cytoskeletal filaments of adjacent cells joint. (Anchoring junction)
|
Intracellular link proteins, they attach the filaments to tranmembrane link proteins. These can interact with similar proteins on adjacent cells. These extracellular interactions may be mediated by additional extracellular proteins or ions such as Calcium ions.
|
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Cadherins
|
Protein that link extracellulary cytoskeletal filaments (link between adjacent cells using Calcium ions).
|
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Adherent junction
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F-actin fibers in adjacent cells are linked by actin-binding proteins, including alpha and beta catenins, vinculin and alpha actinin to a transmembrane protein, which is one of a group of the cadherin family of cell surface glycoproteins which links cells in the presence of Calcium ions.
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|
|
Functions of occluding junctions
|
Prevention of diffusion of molecules between adjacent cells, contributing to the barrier function of epithelial cells.
Prevention of lateral migration of spesialized cell membrane proteins. Delineating (outline) and maintaining specialized cell membrane domains. |
|
|
Actin network interact with 2 separate types of junction:
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Adherent junctions link the actin filament network between adjacent cells
Focal contacts link the actin filament network of a cell to the extracellular matrix |
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By what is the occluding function performed
|
By intermembranous proteins which mediate the adhesion of adjacent cells.
|
|
|
What is occluding junction's other name?
|
Tight junction
|
|
|
What led to the name tight junction?
|
Ultrastructurally an occluding junction is seen as a focal area of close apposition of adjacent cell membrane.
|
|
|
Occluding junction's importance in active transport
|
Prevent back-diffusion (claudin) of tranported substance.
|
|
|
Anchoring junctions
|
Provide mechanical stability to groups of epithelial cells so that they can function as a cohesive unit
|
|
|
Occludal junctions: intermembranous proteins that form these junctions are lines that stitch the membrane of adjacent cells together. Which protein is involved?
|
Occludin
Claudin |
|
|
Through what are cytoskeletal filaments of adjacent cells joint. (Anchoring junction)
|
Intracellular link proteins, they attach the filaments to tranmembrane link proteins. These can interact with similar proteins on adjacent cells. These extracellular interactions may be mediated by additional extracellular proteins or ions such as Calcium ions.
|
|
|
Cadherins
|
Protein that link extracellulary cytoskeletal filaments (link between adjacent cells using Calcium ions).
|
|
|
Adherent junction
|
F-actin fibers in adjacent cells are linked by actin-binding proteins, including alpha and beta catenins, vinculin and alpha actinin to a transmembrane protein, which is one of a group of the cadherin family of cell surface glycoproteins which links cells in the presence of Calcium ions.
|
|
|
Functions of occluding junctions
|
Prevention of diffusion of molecules between adjacent cells, contributing to the barrier function of epithelial cells.
Prevention of lateral migration of spesialized cell membrane proteins. Delineating (outline) and maintaining specialized cell membrane domains. |
|
|
Actin network interact with 2 separate types of junction:
|
Adherent junctions link the actin filament network between adjacent cells
Focal contacts link the actin filament network of a cell to the extracellular matrix |
|
|
The intermediate filament network interacts with 2 separate types of junction:
|
Desmosomes connect the intermediate filament networks of adjacent cells
Hemidesmosomes connect the intermediate filament network of cells to extracellular matrix |
|
|
By what is the occluding function performed
|
By intermembranous proteins which mediate the adhesion of adjacent cells.
|
|
|
What is occluding junction's other name?
|
Tight junction
|
|
|
What led to the name tight junction?
|
Ultrastructurally an occluding junction is seen as a focal area of close apposition of adjacent cell membrane.
|
|
|
Occluding junction's importance in active transport
|
Prevent back-diffusion (claudin) of tranported substance.
|
|
|
Anchoring junctions
|
Provide mechanical stability to groups of epithelial cells so that they can function as a cohesive unit
|
|
|
Occludal junctions: intermembranous proteins that form these junctions are lines that stitch the membrane of adjacent cells together. Which protein is involved?
|
Occludin
Claudin |
|
|
Through what are cytoskeletal filaments of adjacent cells joint. (Anchoring junction)
|
Intracellular link proteins, they attach the filaments to tranmembrane link proteins. These can interact with similar proteins on adjacent cells. These extracellular interactions may be mediated by additional extracellular proteins or ions such as Calcium ions.
|
|
|
Cadherins
|
Protein that link extracellulary cytoskeletal filaments (link between adjacent cells using Calcium ions).
|
|
|
Adherent junction
|
F-actin fibers in adjacent cells are linked by actin-binding proteins, including alpha and beta catenins, vinculin and alpha actinin to a transmembrane protein, which is one of a group of the cadherin family of cell surface glycoproteins which links cells in the presence of Calcium ions.
|
|
|
Functions of occluding junctions
|
Prevention of diffusion of molecules between adjacent cells, contributing to the barrier function of epithelial cells.
Prevention of lateral migration of spesialized cell membrane proteins. Delineating (outline) and maintaining specialized cell membrane domains. |
|
|
Actin network interact with 2 separate types of junction:
|
Adherent junctions link the actin filament network between adjacent cells
Focal contacts link the actin filament network of a cell to the extracellular matrix |
|
|
The intermediate filament network interacts with 2 separate types of junction:
|
Desmosomes connect the intermediate filament networks of adjacent cells
Hemidesmosomes connect the intermediate filament network of cells to extracellular matrix |
|
|
Where are adherent junctions most common
|
Toward the apex of adjacent columnar and cuboidal epithelial cells, where they link submenbranous actin bundles into a so-called adhesion belt.
|
|
|
By what is the occluding function performed
|
By intermembranous proteins which mediate the adhesion of adjacent cells.
|
|
|
What is occluding junction's other name?
|
Tight junction
|
|
|
What led to the name tight junction?
|
Ultrastructurally an occluding junction is seen as a focal area of close apposition of adjacent cell membrane.
|
|
|
Occluding junction's importance in active transport
|
Prevent back-diffusion (claudin) of tranported substance.
|
|
|
Anchoring junctions
|
Provide mechanical stability to groups of epithelial cells so that they can function as a cohesive unit
|
|
|
Occludal junctions: intermembranous proteins that form these junctions are lines that stitch the membrane of adjacent cells together. Which protein is involved?
|
Occludin
Claudin |
|
|
Through what are cytoskeletal filaments of adjacent cells joint. (Anchoring junction)
|
Intracellular link proteins, they attach the filaments to tranmembrane link proteins. These can interact with similar proteins on adjacent cells. These extracellular interactions may be mediated by additional extracellular proteins or ions such as Calcium ions.
|
|
|
Cadherins
|
Protein that link extracellulary cytoskeletal filaments (link between adjacent cells using Calcium ions).
|
|
|
Adherent junction
|
F-actin fibers in adjacent cells are linked by actin-binding proteins, including alpha and beta catenins, vinculin and alpha actinin to a transmembrane protein, which is one of a group of the cadherin family of cell surface glycoproteins which links cells in the presence of Calcium ions.
|
|
|
Functions of occluding junctions
|
Prevention of diffusion of molecules between adjacent cells, contributing to the barrier function of epithelial cells.
Prevention of lateral migration of spesialized cell membrane proteins. Delineating (outline) and maintaining specialized cell membrane domains. |
|
|
Actin network interact with 2 separate types of junction:
|
Adherent junctions link the actin filament network between adjacent cells
Focal contacts link the actin filament network of a cell to the extracellular matrix |
|
|
The intermediate filament network interacts with 2 separate types of junction:
|
Desmosomes connect the intermediate filament networks of adjacent cells
Hemidesmosomes connect the intermediate filament network of cells to extracellular matrix |
|
|
Where are adherent junctions most common
|
Toward the apex of adjacent columnar and cuboidal epithelial cells, where they link submenbranous actin bundles into a so-called adhesion belt.
|
|
|
Where are adhesion belts prominent
|
Cells lining the small intestine, where they form a zone visible by light microscopy as an eosinophilic band - the terminal band.
|
|
|
By what is the occluding function performed
|
By intermembranous proteins which mediate the adhesion of adjacent cells.
|
|
|
What is occluding junction's other name?
|
Tight junction
|
|
|
What led to the name tight junction?
|
Ultrastructurally an occluding junction is seen as a focal area of close apposition of adjacent cell membrane.
|
|
|
Occluding junction's importance in active transport
|
Prevent back-diffusion (claudin) of tranported substance.
|
|
|
Anchoring junctions
|
Provide mechanical stability to groups of epithelial cells so that they can function as a cohesive unit
|
|
|
Occludal junctions: intermembranous proteins that form these junctions are lines that stitch the membrane of adjacent cells together. Which protein is involved?
|
Occludin
Claudin |
|
|
Through what are cytoskeletal filaments of adjacent cells joint. (Anchoring junction)
|
Intracellular link proteins, they attach the filaments to tranmembrane link proteins. These can interact with similar proteins on adjacent cells. These extracellular interactions may be mediated by additional extracellular proteins or ions such as Calcium ions.
|
|
|
Cadherins
|
Protein that link extracellulary cytoskeletal filaments (link between adjacent cells using Calcium ions).
|
|
|
Adherent junction
|
F-actin fibers in adjacent cells are linked by actin-binding proteins, including alpha and beta catenins, vinculin and alpha actinin to a transmembrane protein, which is one of a group of the cadherin family of cell surface glycoproteins which links cells in the presence of Calcium ions.
|
|
|
Functions of occluding junctions
|
Prevention of diffusion of molecules between adjacent cells, contributing to the barrier function of epithelial cells.
Prevention of lateral migration of spesialized cell membrane proteins. Delineating (outline) and maintaining specialized cell membrane domains. |
|
|
Actin network interact with 2 separate types of junction:
|
Adherent junctions link the actin filament network between adjacent cells
Focal contacts link the actin filament network of a cell to the extracellular matrix |
|
|
The intermediate filament network interacts with 2 separate types of junction:
|
Desmosomes connect the intermediate filament networks of adjacent cells
Hemidesmosomes connect the intermediate filament network of cells to extracellular matrix |
|
|
Where are adherent junctions most common
|
Toward the apex of adjacent columnar and cuboidal epithelial cells, where they link submenbranous actin bundles into a so-called adhesion belt.
|
|
|
Where are adhesion belts prominent
|
Cells lining the small intestine, where they form a zone visible by light microscopy as an eosinophilic band - the terminal band.
|
|
|
Embryogenesis and adherent-type junctions
|
In embryogenesis, the adherent-type junctions transmit motile forces genarated by the actin filaments across whole sheets of cells. Thus they are essential in mediating the folding of epithelial sheets to form early organs in the embryo
|
|
|
By what is the occluding function performed
|
By intermembranous proteins which mediate the adhesion of adjacent cells.
|
|
|
What is occluding junction's other name?
|
Tight junction
|
|
|
What led to the name tight junction?
|
Ultrastructurally an occluding junction is seen as a focal area of close apposition of adjacent cell membrane.
|
|
|
Occluding junction's importance in active transport
|
Prevent back-diffusion (claudin) of tranported substance.
|
|
|
Anchoring junctions
|
Provide mechanical stability to groups of epithelial cells so that they can function as a cohesive unit
|
|
|
Occludal junctions: intermembranous proteins that form these junctions are lines that stitch the membrane of adjacent cells together. Which protein is involved?
|
Occludin
Claudin |
|
|
Through what are cytoskeletal filaments of adjacent cells joint. (Anchoring junction)
|
Intracellular link proteins, they attach the filaments to tranmembrane link proteins. These can interact with similar proteins on adjacent cells. These extracellular interactions may be mediated by additional extracellular proteins or ions such as Calcium ions.
|
|
|
Cadherins
|
Protein that link extracellulary cytoskeletal filaments (link between adjacent cells using Calcium ions).
|
|
|
Adherent junction
|
F-actin fibers in adjacent cells are linked by actin-binding proteins, including alpha and beta catenins, vinculin and alpha actinin to a transmembrane protein, which is one of a group of the cadherin family of cell surface glycoproteins which links cells in the presence of Calcium ions.
|
|
|
Functions of occluding junctions
|
Prevention of diffusion of molecules between adjacent cells, contributing to the barrier function of epithelial cells.
Prevention of lateral migration of spesialized cell membrane proteins. Delineating (outline) and maintaining specialized cell membrane domains. |
|
|
Actin network interact with 2 separate types of junction:
|
Adherent junctions link the actin filament network between adjacent cells
Focal contacts link the actin filament network of a cell to the extracellular matrix |
|
|
The intermediate filament network interacts with 2 separate types of junction:
|
Desmosomes connect the intermediate filament networks of adjacent cells
Hemidesmosomes connect the intermediate filament network of cells to extracellular matrix |
|
|
Where are adherent junctions most common
|
Toward the apex of adjacent columnar and cuboidal epithelial cells, where they link submenbranous actin bundles into a so-called adhesion belt.
|
|
|
Where are adhesion belts prominent
|
Cells lining the small intestine, where they form a zone visible by light microscopy as an eosinophilic band - the terminal band.
|
|
|
Embryogenesis and adherent-type junctions
|
In embryogenesis, the adherent-type junctions transmit motile forces genarated by the actin filaments across whole sheets of cells. Thus they are essential in mediating the folding of epithelial sheets to form early organs in the embryo
|
|
|
Focal contact
|
Bundles of actin filaments interact with actin-binding proteins(alpha actin, vinculin, talin) to link with a transmembrane link protein.
|
|
|
Basement membrane
|
Thin layer of connective tissue. Epithelial cells rest on it
|
|
|
By what is the occluding function performed
|
By intermembranous proteins which mediate the adhesion of adjacent cells.
|
|
|
What is occluding junction's other name?
|
Tight junction
|
|
|
What led to the name tight junction?
|
Ultrastructurally an occluding junction is seen as a focal area of close apposition of adjacent cell membrane.
|
|
|
Occluding junction's importance in active transport
|
Prevent back-diffusion (claudin) of tranported substance.
|
|
|
Anchoring junctions
|
Provide mechanical stability to groups of epithelial cells so that they can function as a cohesive unit
|
|
|
Occludal junctions: intermembranous proteins that form these junctions are lines that stitch the membrane of adjacent cells together. Which protein is involved?
|
Occludin
Claudin |
|
|
Through what are cytoskeletal filaments of adjacent cells joint. (Anchoring junction)
|
Intracellular link proteins, they attach the filaments to tranmembrane link proteins. These can interact with similar proteins on adjacent cells. These extracellular interactions may be mediated by additional extracellular proteins or ions such as Calcium ions.
|
|
|
Cadherins
|
Protein that link extracellulary cytoskeletal filaments (link between adjacent cells using Calcium ions).
|
|
|
Adherent junction
|
F-actin fibers in adjacent cells are linked by actin-binding proteins, including alpha and beta catenins, vinculin and alpha actinin to a transmembrane protein, which is one of a group of the cadherin family of cell surface glycoproteins which links cells in the presence of Calcium ions.
|
|
|
Different simple cells
|
Simple squamous epithelium
Simple cuboidal epithelium Simple columnar epithelium |
|
|
Different simple cells
|
Simple squamous epithelium
Simple cuboidal epithelium Simple columnar epithelium |
|
|
Types of psuedostratified cells
|
Pseudostratified columnar epithelium
|
|
|
Different simple cells
|
Simple squamous epithelium
Simple cuboidal epithelium (kidney) Simple columnar epithelium |
|
|
Types of psuedostratified cells
|
Pseudostratified columnar epithelium
|
|
|
Types of stratified cells
|
Stratified squamous epithelium
Stratified cuboidal epithelium Stratified columnar epithelium Trasitional (urothelium) |
|
|
Where is Ciliated columnar epithelium found
|
Uterus
Uterine tubes Smaller bronchi of lungs |
|
|
Where is non-ciliated columnar epithelium found
|
Lining in alimentary canal(digestive canal)
|
|
|
Stratified squamous epithelium structure
|
Cells in superficial part are flattened
Stratum basale- columnar cells Spinosum- polymorphous Planum- several layers of flattened cells |
|
|
Pseudostratified non-ciliated columnar epithelium found ...
|
Male reproductive system
Female urethra |
|
|
Stratified squamous epithelium structure
|
Cells in superficial part are flattened
Stratum basale- columnar cells Spinosum- polymorphous Planum- several layers of flattened cells |
|
|
Pseudostratified non-ciliated columnar epithelium found ...
|
Male reproductive system
Female urethra |
|
|
Pseudostratified ciliated columnarepithelium found...
|
Nasal cavity
Trachea Bronchi |
|
|
3 types of epithelial cell junctions
|
Occluding
Anchoring Communicating |
|
|
Occluding junctions info
|
Well developed in cells lining small bowel
Prevent digested macromolecules from passing between cells Confine specialized areas of cell membrane involved in absorption or secretion to luminal side of cell |
|
|
Communication junctions
|
Allow direct cell to cell communication
Allow selective diffusion of molecules between adjacent cells Found in large numbers during embrygonesis Important is cardiac and smooth muscle cells Pass signals involved in contraction |
|
|
Communication junctions
|
Allow direct cell to cell communication
Allow selective diffusion of molecules between adjacent cells Found in large numbers during embrygonesis Important is cardiac and smooth muscle cells Pass signals involved in contraction |
|
|
Basement membrane
|
Anchors epithelial cells to underlying tissues
Contains special form of matrix protein: type 4 collagen With light microscopy: visible as linear structure at the base of the epithelial cells |
|
|
Communication junctions
|
Allow direct cell to cell communication
Allow selective diffusion of molecules between adjacent cells Found in large numbers during embrygonesis Important is cardiac and smooth muscle cells Pass signals involved in contraction |
|
|
Basement membrane
|
Anchors epithelial cells to underlying tissues
Contains special form of matrix protein: type 4 collagen With light microscopy: visible as linear structure at the base of the epithelial cells |
|
|
Types of secretion glands
|
Serous glands
Mucinous glands Mixed glands |
|
|
Communication junctions
|
Allow direct cell to cell communication
Allow selective diffusion of molecules between adjacent cells Found in large numbers during embrygonesis Important is cardiac and smooth muscle cells Pass signals involved in contraction |
|
|
Basement membrane
|
Anchors epithelial cells to underlying tissues
Contains special form of matrix protein: type 4 collagen With light microscopy: visible as linear structure at the base of the epithelial cells |
|
|
Types of secretion glands
|
Serous glands
Mucinous glands Mixed glands |
|
|
Serous glands
|
Thin, watery.
Pancreas |
|
|
Communication junctions
|
Allow direct cell to cell communication
Allow selective diffusion of molecules between adjacent cells Found in large numbers during embrygonesis Important is cardiac and smooth muscle cells Pass signals involved in contraction |
|
|
Basement membrane
|
Anchors epithelial cells to underlying tissues
Contains special form of matrix protein: type 4 collagen With light microscopy: visible as linear structure at the base of the epithelial cells |
|
|
Types of secretion glands
|
Serous glands
Mucinous glands Mixed glands |
|
|
Serous glands
|
Thin, watery.
Pancreas |
|
|
Mucinous glands
|
Thick, mucinous secretion
Lingual tonsil, duodenum |
|
|
Communication junctions
|
Allow direct cell to cell communication
Allow selective diffusion of molecules between adjacent cells Found in large numbers during embrygonesis Important is cardiac and smooth muscle cells Pass signals involved in contraction |
|
|
Basement membrane
|
Anchors epithelial cells to underlying tissues
Contains special form of matrix protein: type 4 collagen With light microscopy: visible as linear structure at the base of the epithelial cells |
|
|
Types of secretion glands
|
Serous glands
Mucinous glands Mixed glands |
|
|
Serous glands
|
Thin, watery.
Pancreas |
|
|
Mucinous glands
|
Thick, mucinous secretion
Lingual tonsil, duodenum |
|
|
Mixed glands
|
Thick, mucinous and thin, watery
Submandibular and sublingual salvary glands |
|
|
Communication junctions
|
Allow direct cell to cell communication
Allow selective diffusion of molecules between adjacent cells Found in large numbers during embrygonesis Important is cardiac and smooth muscle cells Pass signals involved in contraction |
|
|
Basement membrane
|
Anchors epithelial cells to underlying tissues
Contains special form of matrix protein: type 4 collagen With light microscopy: visible as linear structure at the base of the epithelial cells |
|
|
Types of secretion glands
|
Serous glands
Mucinous glands Mixed glands |
|
|
Serous glands
|
Thin, watery.
Pancreas |
|
|
Mucinous glands
|
Thick, mucinous secretion
Lingual tonsil, duodenum |
|
|
Mixed glands
|
Thick, mucinous and thin, watery
Submandibular and sublingual salvary glands |
|
|
4 Types of epithelial secretion
|
Merocrine - cell products via exocytosis
Apocrine- part of cytoplasm pinch off Holocrine - shedding of whole cell containing product Endocrine - endocytosis from cell into blood stream |
|
|
Goblet cells
|
Single secretory cells (grandular epithelium)
|
|
|
Crypts of Lieberkuhn
|
Straight tubular glands
In intestine |
|
|
Sweat glands
|
Coiled tubular glands
|
|
|
Crypts of Lieberkuhn
|
Straight tubular glands
In intestine |
|
|
Sweat glands
|
Coiled tubular glands
|
|
|
Mammary glands
|
Branched glands
|
