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153 Cards in this Set

  • Front
  • Back
how much more do you breathe than eat/drink?
6 times more
what is the 3rd leading cause of death in the U.S?
lung disease
what is the most common chronic illness in children?
asthma
types of air pollutants
natural: ash, radioactivity, pollen, smoke; manmade: gaseous; particulate matter - solid or aq; smallest can remain suspended in lungs (can be toxic or vectors for other toxins)
sources of cost of health poln:
health, worker productivity, agricult
total cost of air poln:
$71 bil from criteria air pollutants
clean air act established 2 broad classes of air pollutants:
"criteria" pollutants - threshold, 6 types: PM, SO2, Pb, NO2, O3, CO; omnipresent + not too toxic vs "hazardous air pollutants" - potentially carcinogenic, industry spec, no accept level
main source + type of primary air pollutant
transportation; CO
T/F: we have been successful at regulating criteria air pollutants
True! growth has been dec
ex of a primary air pollutant --> transforming to secondary
NO2 + hydrocarbon + sunlight --> O3 in lower atm (or SO2 --> oxidized to aerosoles)
how much more do you breathe than eat/drink?
6 times more
what is the 3rd leading cause of death in the U.S?
lung disease
what is the most common chronic illness in children?
asthma
types of air pollutants
natural: ash, radioactivity, pollen, smoke; manmade: gaseous; particulate matter - solid or aq; smallest can remain suspended in lungs (can be toxic or vectors for other toxins)
sources of cost of health poln:
health, worker productivity, agricult
total cost of air poln:
$71 bil from criteria air pollutants
clean air act established 2 broad classes of air pollutants:
"criteria" pollutants - threshold, 6 types: PM, SO2, Pb, NO2, O3, CO; omnipresent + not too toxic vs "hazardous air pollutants" - potentially carcinogenic, industry spec, no accept level
main source + type of primary air pollutant
transportation; CO
T/F: we have been successful at regulating criteria air pollutants
True! growth has been dec
ex of a primary air pollutant --> transforming to secondary
NO2 + hydrocarbon + sunlight --> O3 in lower atm (or SO2 --> oxidized to aerosoles)
what is an inversion layer?
instead of hot air --> cooler air --> cold air, hot air is in mid so traps pollutants/smog
NAAQS criteria level set at ...
level for sensitive populations
pulmonary responses to toxicants:
1.) local irritation (edema = fluid buildiup, bronchial constriction 2.) bronchitis 3.) necrosis (cell death) result of damage to cells in airway 4.) fibrosis + emphysema, loss of lung elasticity 5.) lung cancer (ozone = promoter? not itself a carcinogenic)
acute vs long-term exposure to ozone
acute: irritation, inflamation, asthma; chronic = impaired growth + dev of lung, accel lung aging (oxidation of cellular components), contributes to progression of underlying lung D+
What does NAAQS stand for?
National Ambient Air Quality Standards
EPA sets standards for all ____ risks
potential, identifiable (not necessary proven)
CO risk esp for people with ___
cardiovasc D+ (prevents O2 from binding to Hb)
2 issues central to standard setting
a.) adequate margin of safety (precautious) b.) concept of threshold
criteria pollutants and their susceptible sub-pops:
SO2: people with inc airway reactivity (asthmatics); CO - heart probs; Pb - kids; PM - elderly + kids; NO2 - kids, O3 - active people
strategies for implementing standards
new tech.; modify products; restrict use; bans; disclose risks; economic incentives
how many HAPS are there? examples?
188, heavy metals, organics
Air Toxics Sources
area sources (neighborhoods); mobile; large industrial complexes point sources (61%)
b/c no threshold, ___ is inappropriate for HAPs so use ____
air quality standards; site-specific emissions standards (provide AMPLE margin of safety, not adequate like w/ criteria pollutants)
HAPs Technology-Based Standards
standards set according to what's achievable w/ available tech, not based on health (residual risks det after the fact)
why is indoor air polln a concern?
75 - 80% time spent indoors, indoor levels can be 2 - 5 times higher than outdoors
air inside building can be pol at result of
poor vent, low air-exchange rate w/ outdoors, biogenic pollutants (aeropathogens/allergens), human activity, occupancy, gas-off from synthetic building mats, poor housing conditions
major indoor air pollutants of concern
odors, radon, biological pollutants, combustion, volatile chems/chem mixs
biggest source of CO, HCO, and PM from fuel is from ...
wood
major source of E and heating in developing world =
biofuels (petroleum in developed worlds)
T/F many chems are more present in side smoke than main smoke
T: ETS is a major source of toxic + carcinogenic agents that are less completely combusted in SS than MS
ETS stands for
environmental tobacco smoke
fetal affects of non-smoking mothers exposed to ETS
lower birth weight, defects, congenital malformations, inc risk of SIDS, red lung function in kids
VOCs =
volatile organic compounds
exs of biogenic pollutants
mites, aeroallergens, aeropathogens
health effects of indoor air pollutants
irritation, respiratory symptoms, neurological symptoms, immunological rxns, asthma, cancer
4 results of energy-efficient buildings
inc odor, humidity, temp; dec vent
building related illness vs sick building syndrome
D+ traceable to spec pollutant vs > 20% occupants have dec symptoms when leave building (inc symptoms w/ inc time in building)
SO2 source differs from NO2 source in that
it comes largely from fossil fuel combustion in coal mine
ionizing vs non-ionizing radiation
ability to knock e- off (particulates, electromagnetics: x-rays, gamma rays) or not (electromagnetics: UV, microwaves, EMF's)
electromagnetic vs particulate radiation
no mass, no charge (ex UV, vis light, x-rays) vs yes (alpha, beta, neutrons)
how do EMFs probs affect bio systems?
indirectly by interfering w/ molec interactions (but can't see direct effect on DNA - changes in synthesis/transcription)
criteria to establish causality
temporality, dose response, bio plausibility
epigenetic mech
things happen to and around gene w/o directly altering DNA sequence (unlike old cancer hypotheses)
melatonin hypothesis
sources of ionizing radiation
radionuclides (radioactive decay) and machines (e-, x-ray machines - can be turned on + off)
most dangerous type of irradiation inside vs outside body (source)
inside source: alpha and beta particles worst; outside: gamma and x-rays
radiation effects
deterministic (dose-response based severity, threshold) vs random (risk = function of dose, not severity - ex cancer)
best known carcinogen
ionizing radiation (physical agent)
why do we extrapolate out a straight line for cancer dose-response curve?
most conservative - predicts highest response for given dose (overprotect pub)
what would graph look like if dose broke 1 strand of DNA vs broke 2 and effect was both strands breaking?
linear vs quadratic - second one is prob of 2 indep events
hormesis + ex.
protective effects of exposure at very low doses - ex = low levels of mutagenic will excite DNA repair + fix old problems = net benefit
exposure = (eq)
intensity * time
how does intensity relate to distance and shielding?
I drops with distance via square inverse law; dec as shielding inc (can totally shield vs particulate matter + exponentially vs electromagnteic radiation)
2 potential consequences to cells as result of radiation carcinogenesis
cell death or damage --> repair or altered function
most vs least sensitive cells
mitotic (no DNA repair) vs s (synthesis) phase
only dif b/w fossil fuel + nuclear power plant
material used to heat water to generate steam to turn turbines that generate electricity
fossil fuel plants put more ____ into air than nuc power plants
radiation (on a reg basis) but severity of nuc power plant acc is much more
2 factors that drive risk perception
threat (vol/invol, severity) and observability
radiation and risk perception:
invol expos, unknown conseq, delayed conseq, no benefits, unknown expo
5 kinds of waste
Munincipal (residential, small business, schools), Industrial (includes agricultural), Medical, Hazardous, Radioactive
what kind of waste is the most?
industrial - 94%
most common source of hazardous waste in household waste
from automobiles (then paint)
causes for u.s's exponentially increasing waste produc
no econ incentive to reduce, convenience, urbanization
most of waste disposed of via
landfills (vs incineration and recycle)
problem with landfills
unsanitary - w/o plastic liner + monitoring can leak into groundwater (leachate)
3 reasons new landfills aren't being created
public opposition, rising costs, EPA regulations
does MSW degrade in a landfill? why/why not?
not readily b/c a.) get rid of leachate b.) compact so no O2 can decompose them c.) "biodegradable" only applies if enough oxygen to degrade them
#1 component of typical sanitary landfill leachate composition
BOD5 (amt of oxygen utilized by bacteria to oxidize organic compounds in dark in 5 days at 20 degrees celsius) - reduce in waste water plants
incineration reduces trash vol by
80 - 90%
incineration reduces waste to
solids (dispose of), gasses, water vapor
incinerators compact trash + ___
can gen cheap E for local businesses
3 reasons to recycle
resource, energy conservation (50 - 60% less E than make from virgin material) + pollution abatement
2 things better than recycling
reducing, reusing
have we inc or dec our recycling? trash?
inc recycle, inc trash
munincipal waste management hierarchy: ranked in order of increasing impact on the enviro:
reduce, reuse, recycle, incinerate + E, incinerate - E, landfill
characteristics of hazardous waste
flammable (fp < 140 faren), toxic, corrosive (super acidic/basic), reactive
RCRA
Resource Conservation and Recovery Act: regulated what's toxic + where it goes
CERCLA
established national priority list for superfund $
what is responsible for most hazardous waste?
chemical industry
how much haz waste is wat diluted with haz mats?
90%
biggest poten health impact that leads to mat being on NPL
affect ground + drinking water
Love Canal Study
school built on top of toxic dumping site --> acid burns
problems w/ enviro contam + pub health assess
in many cases, residence next to source does not equal exposure
probs with cleaning up old site
who pays? "polluter pays" - 30% superfund $ spent fighting them so taxpayer ends up bearing most of burden, how clean is clean enough
modes of transport of haz mats
flat-bed trucks, cargo tanks, barges, planes
3 concerns from animal manure (compounds):
phosphorous, nitrogen (vectors?), pathogens
# of animal farms vs animals/farm
dec, inc
types of polln prod by animals
water poln (drinking + streams, coasts), air polln (nitrogen), odor poll (amon)
poten threats to pub health b/c of animals in meat produc factories
pathogens, toxicants (known + unknown), antibac resist, heavy metals in waste lagoons, greenhouse gasses
munincipal vs hog farm waste treatment reg
hog farms not subject to quality control or enviro control - inspected by officials once every 2 yrs
main obstacles to enviro cleanup:
lack of $ (superfund), reluctance to accept respons, incomplete sceince (lack of epi studies)
mortality due to typhoid decreased drastically b/c of __
chlorination of water
how much water is fresh and how much is usable by humans?
2.5, .3%
how much water do you need for the 4 basic needs and what are they?
50 - 100 L: bathing, sanitation, cooking, drinking
water stress vs water scarcity
1000 - 1700 m^3 renewable fresh water/person/yr; <1000 (groundwater is NON-RENEWABLE)
population in water scarce/stressed countries is __
rising
3 main uses of freshwater (leading one is…)
agriculture (70%), industry, domestic (personal, munincipal, household)
majority of freshwater use in U.S is for
outdoor use - lawns, cars, etc
sources of water pollutants (leading one is..)
agriculture - farming responsible for 70% water polln in U.S!! Industry, munincipalities
CAFO =
concentrated animal farming operation
Clean Water Act did 2 things:
1.) regulate industries/cities to meet "0 discharge of poln" goal 2.) provide fed assistance to do this
TMDL =
total maximum daily load = state set line of how much poln a given body of water can receive/day w/o violating quality standards
Safe Drinking Water Act did what
regulates PUBLIC drinking water - to protect pub health (vs enviro like CWA does); lets USEPA set legally enforceable standards
gastrointestinal diseases cause more/less morbid than mortal
MORE
every ___ sec a child dies of diarrhea
15 sec
____ % gastrointestinal illness could be prev by adeq hygiene + sanit
90%
three grousp of microorganisms + 2 factors that relate to them
viruses, bac, parasites; size + resistivity
list of 3 groups of microorganisms in size + then resistivity
bac > para > vir BUT for resist it's para > vir > bac
steps for water treatment
coagulation --> floculation --> sedimentation --> filtration --> disinfection --> distribution
coagulation
mixing of water with chems (aluminum sulfate) --> make gelatinous mass w/ suspended particles= floc
floculation
stir mix slower --> make bigger particles to trap other sediments + stuff
sedimentation
let floc stuff settle to bottom
filtration
rapid sand (anthracite) + stuff to filter thru (backwash water --> sewer)
disinfection
to a level where can't identify D+ causing pathogens;
types of disinfectants + their pros/cons
chlorine (cheap, residual but doesn't get everything like crypto + poten carcinogenic DBP); ozone (good disin + fewer byprod (DBP)'s but no resid + expensive); UV rad (good, no DBPs but no resid, can't work w/ turbid water)
what does Cl react w/ to make DBP?
humics = organic compounds (remove these first)
why is residual so important?
to keep water disinfec from source --> deliv (bad pipes, leakage, backwash, etc)
what's used to det microbiological qual of drinking water?
bacterial indicators - fast, cheap, easy but not best b/c more easily elim than virus or para
bottled water is reg by…
FDA - NOT EPA (only reg ground + surface drinking water)
aim of wastewater treatment
disinfect to pt where won't cause serious enviro or health probs via waterborne D+
in developing countries ___ % domestic sewage and ___ % industrial waste are dumped into surface water w/o treatment
90% domestic, 75% industrial waste
wastewater components of concern (5)
pathogens, BOD, Suspended Solids, Nutrients, Toxic Chems
what is BOD and what levels (high/low) are good?
biochemical oxygen demand = oxygen demand of bac to ox organic and inorganic mat; high level = poll by bac (uses up all dissolved oxygen and --> dead zones)
3 main levels of wastewater treatment
primary (filtration), secondary (oxidation + decomp by bac), tert (physiochem - remove additional compounds)
what happens to sludge separated from wastewater via filtration?
gets heated, compacted, sent to landfills
2 main concerns from exposure to Ground zero
lymphatic and blood cancers (+ respiratory failure)
exposure assessment elements
target, duration, frequency, concentration, location, source/composition
what generated the WTC contaminants?
particulate matter, volatile compounds (esp fluids), gasses (freon)
hand in hand w/ Health Exposure Elements is
Health Assessment Elements (did expos affect us neg?)
3 phase effort by JHSPH WTC response team
exposure assess, respiratory health survey (provide info about acute expos + baseline for long term follow up), health assess (2 yrs post cleanup)
20 mo after leaving site workers were still at inc risk for _____
lower resp problems + mental health
T/F inc duration at site inc risk for dev resp probs
true! indicates need for better site management
T/F: there is a strong linkage b/w clinical, epi, and exposure comm.s for WTC surveys
false! lot of holes in the research
sources of mercury
degassing of E's crust, fish, amalgam fillings, combustion of fossil fuels, industrial release
why isn't dental mercury a problem if swallowed?
elem Hg can't cross GI tract (slow) - dangerous if inhale b/c can cross blood-brain barrier (lipid sol!) targets lungs + CNS
inorganic merc probs
mad hatter syndrome: not lipid sol but can cross GI tract (10%) - expos thru ingestion
organic merc probs
easily cross GI, lipid sol (prob for fetuses), high affin for CNS
how does elem Hg end up in us?
indust release elem Hg --> complexes to inorg --> bac turn to org --> eaten by phytoplank + big fish
results of adding Hg to lake 658?
watershed Hg stayed in plants (would take centuries to flush out); lake Hg rapidly entered food chain --> would take decades to flush out of enviro
Minamata Bay
industrial Hg (byproduc of acetylaldehyde produc) dumped x4/day --> bay
symptoms of Hg poisoning
claws, cerebral palsy, neuro damage
Iraq
seeds laced w/ Hg anti-fungal meant to be planted were eaten in rural villages
mercury level in rain - how does MD stack up?
highest among mid-S Atlantic states