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153 Cards in this Set
- Front
- Back
how much more do you breathe than eat/drink?
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6 times more
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what is the 3rd leading cause of death in the U.S?
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lung disease
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what is the most common chronic illness in children?
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asthma
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types of air pollutants
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natural: ash, radioactivity, pollen, smoke; manmade: gaseous; particulate matter - solid or aq; smallest can remain suspended in lungs (can be toxic or vectors for other toxins)
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sources of cost of health poln:
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health, worker productivity, agricult
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total cost of air poln:
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$71 bil from criteria air pollutants
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clean air act established 2 broad classes of air pollutants:
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"criteria" pollutants - threshold, 6 types: PM, SO2, Pb, NO2, O3, CO; omnipresent + not too toxic vs "hazardous air pollutants" - potentially carcinogenic, industry spec, no accept level
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main source + type of primary air pollutant
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transportation; CO
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T/F: we have been successful at regulating criteria air pollutants
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True! growth has been dec
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ex of a primary air pollutant --> transforming to secondary
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NO2 + hydrocarbon + sunlight --> O3 in lower atm (or SO2 --> oxidized to aerosoles)
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how much more do you breathe than eat/drink?
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6 times more
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what is the 3rd leading cause of death in the U.S?
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lung disease
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what is the most common chronic illness in children?
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asthma
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types of air pollutants
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natural: ash, radioactivity, pollen, smoke; manmade: gaseous; particulate matter - solid or aq; smallest can remain suspended in lungs (can be toxic or vectors for other toxins)
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sources of cost of health poln:
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health, worker productivity, agricult
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total cost of air poln:
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$71 bil from criteria air pollutants
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clean air act established 2 broad classes of air pollutants:
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"criteria" pollutants - threshold, 6 types: PM, SO2, Pb, NO2, O3, CO; omnipresent + not too toxic vs "hazardous air pollutants" - potentially carcinogenic, industry spec, no accept level
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main source + type of primary air pollutant
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transportation; CO
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T/F: we have been successful at regulating criteria air pollutants
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True! growth has been dec
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ex of a primary air pollutant --> transforming to secondary
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NO2 + hydrocarbon + sunlight --> O3 in lower atm (or SO2 --> oxidized to aerosoles)
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what is an inversion layer?
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instead of hot air --> cooler air --> cold air, hot air is in mid so traps pollutants/smog
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NAAQS criteria level set at ...
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level for sensitive populations
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pulmonary responses to toxicants:
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1.) local irritation (edema = fluid buildiup, bronchial constriction 2.) bronchitis 3.) necrosis (cell death) result of damage to cells in airway 4.) fibrosis + emphysema, loss of lung elasticity 5.) lung cancer (ozone = promoter? not itself a carcinogenic)
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acute vs long-term exposure to ozone
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acute: irritation, inflamation, asthma; chronic = impaired growth + dev of lung, accel lung aging (oxidation of cellular components), contributes to progression of underlying lung D+
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What does NAAQS stand for?
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National Ambient Air Quality Standards
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EPA sets standards for all ____ risks
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potential, identifiable (not necessary proven)
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CO risk esp for people with ___
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cardiovasc D+ (prevents O2 from binding to Hb)
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2 issues central to standard setting
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a.) adequate margin of safety (precautious) b.) concept of threshold
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criteria pollutants and their susceptible sub-pops:
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SO2: people with inc airway reactivity (asthmatics); CO - heart probs; Pb - kids; PM - elderly + kids; NO2 - kids, O3 - active people
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strategies for implementing standards
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new tech.; modify products; restrict use; bans; disclose risks; economic incentives
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how many HAPS are there? examples?
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188, heavy metals, organics
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Air Toxics Sources
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area sources (neighborhoods); mobile; large industrial complexes point sources (61%)
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b/c no threshold, ___ is inappropriate for HAPs so use ____
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air quality standards; site-specific emissions standards (provide AMPLE margin of safety, not adequate like w/ criteria pollutants)
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HAPs Technology-Based Standards
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standards set according to what's achievable w/ available tech, not based on health (residual risks det after the fact)
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why is indoor air polln a concern?
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75 - 80% time spent indoors, indoor levels can be 2 - 5 times higher than outdoors
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air inside building can be pol at result of
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poor vent, low air-exchange rate w/ outdoors, biogenic pollutants (aeropathogens/allergens), human activity, occupancy, gas-off from synthetic building mats, poor housing conditions
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major indoor air pollutants of concern
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odors, radon, biological pollutants, combustion, volatile chems/chem mixs
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biggest source of CO, HCO, and PM from fuel is from ...
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wood
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major source of E and heating in developing world =
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biofuels (petroleum in developed worlds)
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T/F many chems are more present in side smoke than main smoke
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T: ETS is a major source of toxic + carcinogenic agents that are less completely combusted in SS than MS
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ETS stands for
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environmental tobacco smoke
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fetal affects of non-smoking mothers exposed to ETS
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lower birth weight, defects, congenital malformations, inc risk of SIDS, red lung function in kids
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VOCs =
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volatile organic compounds
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exs of biogenic pollutants
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mites, aeroallergens, aeropathogens
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health effects of indoor air pollutants
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irritation, respiratory symptoms, neurological symptoms, immunological rxns, asthma, cancer
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4 results of energy-efficient buildings
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inc odor, humidity, temp; dec vent
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building related illness vs sick building syndrome
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D+ traceable to spec pollutant vs > 20% occupants have dec symptoms when leave building (inc symptoms w/ inc time in building)
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SO2 source differs from NO2 source in that
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it comes largely from fossil fuel combustion in coal mine
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ionizing vs non-ionizing radiation
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ability to knock e- off (particulates, electromagnetics: x-rays, gamma rays) or not (electromagnetics: UV, microwaves, EMF's)
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electromagnetic vs particulate radiation
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no mass, no charge (ex UV, vis light, x-rays) vs yes (alpha, beta, neutrons)
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how do EMFs probs affect bio systems?
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indirectly by interfering w/ molec interactions (but can't see direct effect on DNA - changes in synthesis/transcription)
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criteria to establish causality
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temporality, dose response, bio plausibility
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epigenetic mech
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things happen to and around gene w/o directly altering DNA sequence (unlike old cancer hypotheses)
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melatonin hypothesis
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sources of ionizing radiation
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radionuclides (radioactive decay) and machines (e-, x-ray machines - can be turned on + off)
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most dangerous type of irradiation inside vs outside body (source)
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inside source: alpha and beta particles worst; outside: gamma and x-rays
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radiation effects
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deterministic (dose-response based severity, threshold) vs random (risk = function of dose, not severity - ex cancer)
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best known carcinogen
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ionizing radiation (physical agent)
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why do we extrapolate out a straight line for cancer dose-response curve?
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most conservative - predicts highest response for given dose (overprotect pub)
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what would graph look like if dose broke 1 strand of DNA vs broke 2 and effect was both strands breaking?
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linear vs quadratic - second one is prob of 2 indep events
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hormesis + ex.
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protective effects of exposure at very low doses - ex = low levels of mutagenic will excite DNA repair + fix old problems = net benefit
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exposure = (eq)
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intensity * time
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how does intensity relate to distance and shielding?
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I drops with distance via square inverse law; dec as shielding inc (can totally shield vs particulate matter + exponentially vs electromagnteic radiation)
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2 potential consequences to cells as result of radiation carcinogenesis
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cell death or damage --> repair or altered function
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most vs least sensitive cells
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mitotic (no DNA repair) vs s (synthesis) phase
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only dif b/w fossil fuel + nuclear power plant
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material used to heat water to generate steam to turn turbines that generate electricity
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fossil fuel plants put more ____ into air than nuc power plants
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radiation (on a reg basis) but severity of nuc power plant acc is much more
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2 factors that drive risk perception
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threat (vol/invol, severity) and observability
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radiation and risk perception:
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invol expos, unknown conseq, delayed conseq, no benefits, unknown expo
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5 kinds of waste
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Munincipal (residential, small business, schools), Industrial (includes agricultural), Medical, Hazardous, Radioactive
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what kind of waste is the most?
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industrial - 94%
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most common source of hazardous waste in household waste
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from automobiles (then paint)
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causes for u.s's exponentially increasing waste produc
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no econ incentive to reduce, convenience, urbanization
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most of waste disposed of via
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landfills (vs incineration and recycle)
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problem with landfills
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unsanitary - w/o plastic liner + monitoring can leak into groundwater (leachate)
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3 reasons new landfills aren't being created
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public opposition, rising costs, EPA regulations
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does MSW degrade in a landfill? why/why not?
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not readily b/c a.) get rid of leachate b.) compact so no O2 can decompose them c.) "biodegradable" only applies if enough oxygen to degrade them
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#1 component of typical sanitary landfill leachate composition
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BOD5 (amt of oxygen utilized by bacteria to oxidize organic compounds in dark in 5 days at 20 degrees celsius) - reduce in waste water plants
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incineration reduces trash vol by
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80 - 90%
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incineration reduces waste to
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solids (dispose of), gasses, water vapor
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incinerators compact trash + ___
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can gen cheap E for local businesses
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3 reasons to recycle
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resource, energy conservation (50 - 60% less E than make from virgin material) + pollution abatement
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2 things better than recycling
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reducing, reusing
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have we inc or dec our recycling? trash?
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inc recycle, inc trash
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munincipal waste management hierarchy: ranked in order of increasing impact on the enviro:
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reduce, reuse, recycle, incinerate + E, incinerate - E, landfill
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characteristics of hazardous waste
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flammable (fp < 140 faren), toxic, corrosive (super acidic/basic), reactive
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RCRA
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Resource Conservation and Recovery Act: regulated what's toxic + where it goes
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CERCLA
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established national priority list for superfund $
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what is responsible for most hazardous waste?
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chemical industry
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how much haz waste is wat diluted with haz mats?
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90%
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biggest poten health impact that leads to mat being on NPL
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affect ground + drinking water
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Love Canal Study
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school built on top of toxic dumping site --> acid burns
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problems w/ enviro contam + pub health assess
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in many cases, residence next to source does not equal exposure
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probs with cleaning up old site
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who pays? "polluter pays" - 30% superfund $ spent fighting them so taxpayer ends up bearing most of burden, how clean is clean enough
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modes of transport of haz mats
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flat-bed trucks, cargo tanks, barges, planes
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3 concerns from animal manure (compounds):
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phosphorous, nitrogen (vectors?), pathogens
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# of animal farms vs animals/farm
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dec, inc
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types of polln prod by animals
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water poln (drinking + streams, coasts), air polln (nitrogen), odor poll (amon)
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poten threats to pub health b/c of animals in meat produc factories
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pathogens, toxicants (known + unknown), antibac resist, heavy metals in waste lagoons, greenhouse gasses
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munincipal vs hog farm waste treatment reg
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hog farms not subject to quality control or enviro control - inspected by officials once every 2 yrs
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main obstacles to enviro cleanup:
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lack of $ (superfund), reluctance to accept respons, incomplete sceince (lack of epi studies)
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mortality due to typhoid decreased drastically b/c of __
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chlorination of water
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how much water is fresh and how much is usable by humans?
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2.5, .3%
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how much water do you need for the 4 basic needs and what are they?
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50 - 100 L: bathing, sanitation, cooking, drinking
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water stress vs water scarcity
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1000 - 1700 m^3 renewable fresh water/person/yr; <1000 (groundwater is NON-RENEWABLE)
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population in water scarce/stressed countries is __
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rising
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3 main uses of freshwater (leading one is…)
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agriculture (70%), industry, domestic (personal, munincipal, household)
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majority of freshwater use in U.S is for
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outdoor use - lawns, cars, etc
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sources of water pollutants (leading one is..)
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agriculture - farming responsible for 70% water polln in U.S!! Industry, munincipalities
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CAFO =
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concentrated animal farming operation
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Clean Water Act did 2 things:
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1.) regulate industries/cities to meet "0 discharge of poln" goal 2.) provide fed assistance to do this
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TMDL =
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total maximum daily load = state set line of how much poln a given body of water can receive/day w/o violating quality standards
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Safe Drinking Water Act did what
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regulates PUBLIC drinking water - to protect pub health (vs enviro like CWA does); lets USEPA set legally enforceable standards
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gastrointestinal diseases cause more/less morbid than mortal
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MORE
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every ___ sec a child dies of diarrhea
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15 sec
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____ % gastrointestinal illness could be prev by adeq hygiene + sanit
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90%
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three grousp of microorganisms + 2 factors that relate to them
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viruses, bac, parasites; size + resistivity
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list of 3 groups of microorganisms in size + then resistivity
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bac > para > vir BUT for resist it's para > vir > bac
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steps for water treatment
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coagulation --> floculation --> sedimentation --> filtration --> disinfection --> distribution
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coagulation
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mixing of water with chems (aluminum sulfate) --> make gelatinous mass w/ suspended particles= floc
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floculation
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stir mix slower --> make bigger particles to trap other sediments + stuff
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sedimentation
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let floc stuff settle to bottom
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filtration
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rapid sand (anthracite) + stuff to filter thru (backwash water --> sewer)
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disinfection
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to a level where can't identify D+ causing pathogens;
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types of disinfectants + their pros/cons
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chlorine (cheap, residual but doesn't get everything like crypto + poten carcinogenic DBP); ozone (good disin + fewer byprod (DBP)'s but no resid + expensive); UV rad (good, no DBPs but no resid, can't work w/ turbid water)
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what does Cl react w/ to make DBP?
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humics = organic compounds (remove these first)
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why is residual so important?
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to keep water disinfec from source --> deliv (bad pipes, leakage, backwash, etc)
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what's used to det microbiological qual of drinking water?
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bacterial indicators - fast, cheap, easy but not best b/c more easily elim than virus or para
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bottled water is reg by…
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FDA - NOT EPA (only reg ground + surface drinking water)
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aim of wastewater treatment
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disinfect to pt where won't cause serious enviro or health probs via waterborne D+
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in developing countries ___ % domestic sewage and ___ % industrial waste are dumped into surface water w/o treatment
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90% domestic, 75% industrial waste
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wastewater components of concern (5)
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pathogens, BOD, Suspended Solids, Nutrients, Toxic Chems
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what is BOD and what levels (high/low) are good?
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biochemical oxygen demand = oxygen demand of bac to ox organic and inorganic mat; high level = poll by bac (uses up all dissolved oxygen and --> dead zones)
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3 main levels of wastewater treatment
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primary (filtration), secondary (oxidation + decomp by bac), tert (physiochem - remove additional compounds)
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what happens to sludge separated from wastewater via filtration?
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gets heated, compacted, sent to landfills
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2 main concerns from exposure to Ground zero
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lymphatic and blood cancers (+ respiratory failure)
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exposure assessment elements
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target, duration, frequency, concentration, location, source/composition
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what generated the WTC contaminants?
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particulate matter, volatile compounds (esp fluids), gasses (freon)
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hand in hand w/ Health Exposure Elements is
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Health Assessment Elements (did expos affect us neg?)
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3 phase effort by JHSPH WTC response team
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exposure assess, respiratory health survey (provide info about acute expos + baseline for long term follow up), health assess (2 yrs post cleanup)
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20 mo after leaving site workers were still at inc risk for _____
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lower resp problems + mental health
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T/F inc duration at site inc risk for dev resp probs
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true! indicates need for better site management
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T/F: there is a strong linkage b/w clinical, epi, and exposure comm.s for WTC surveys
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false! lot of holes in the research
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sources of mercury
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degassing of E's crust, fish, amalgam fillings, combustion of fossil fuels, industrial release
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why isn't dental mercury a problem if swallowed?
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elem Hg can't cross GI tract (slow) - dangerous if inhale b/c can cross blood-brain barrier (lipid sol!) targets lungs + CNS
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inorganic merc probs
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mad hatter syndrome: not lipid sol but can cross GI tract (10%) - expos thru ingestion
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organic merc probs
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easily cross GI, lipid sol (prob for fetuses), high affin for CNS
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how does elem Hg end up in us?
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indust release elem Hg --> complexes to inorg --> bac turn to org --> eaten by phytoplank + big fish
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results of adding Hg to lake 658?
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watershed Hg stayed in plants (would take centuries to flush out); lake Hg rapidly entered food chain --> would take decades to flush out of enviro
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Minamata Bay
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industrial Hg (byproduc of acetylaldehyde produc) dumped x4/day --> bay
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symptoms of Hg poisoning
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claws, cerebral palsy, neuro damage
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Iraq
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seeds laced w/ Hg anti-fungal meant to be planted were eaten in rural villages
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mercury level in rain - how does MD stack up?
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highest among mid-S Atlantic states
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