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86 Cards in this Set
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- Back
- 3rd side (hint)
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Opportunistic patogen |
Citrobacter, enterobacter, escherichia, morganella, providencia,serratia, proteus |
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Opportunistic pathogen menyebabkan |
Septicemia, pneumonia, meningitis, Dan uti |
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True pathogen |
Salmonella, shigella, yersinia, dan bbrp e.coli |
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Ini apa |
E. Coli |
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ciri e. Coli |
Flora normal pada intestine, gram negative, |
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Uji biokimia ecoli |
Indol (+) , asetat (+) , peragian laktosa (+), gas & glukosa (+), lisin dekarboksilase (+/-), motilitas (+/-), hemolisis tipe B (+/-) |
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Indol (+) , asetat (+) , peragian laktosa (+), gas & glukosa (+), lisin dekarboksilase (+/-), motilitas (+/-), hemolisis tipe B (+/-) Merupakan ciri biokimiawi bakteri |
E coli |
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E coli berbahaya atau tidak |
Kebanyakan tidak |
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E. Coli yg berbahaya menyebabkan |
Uti, diarrhea (epec, etec, ehec, eiec, eaec), sepsis, meningitis pd balita |
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Enterovirulent e. Coli berdasarkan aksinya di git (5) |
1. Enteropathogenic (epec), 2. enterotoxigenic (etec), 3. enteroinvasive (eiec), 4. enterohaemorrhagic (ehec), 5. enteroaggregative (eaec) |
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Definisi enteropathogenic (epec) |
Responsible for severe infantile diarrhoea A/E (attaching-effacing) mechanism |
E. Coli |
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Definisi enterotoxigenic (ETEC) |
Produces a heat labile (LT) or heat stable (ST) toxin. Both may be produced by the same organism. They are responsible for cases of paediatric diarrhoea, severe cholera-like illness, and travellers diarrhoea (watery diarrhea, febrile, nausea) (small intestine) |
E. Coli |
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Definisi enteroinvasive (eiec) |
Pathogenicity is due to invasion of the gut mucosa. They give rise to a dysentery-like illness |
E.coli |
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Definisi enterohaemorrhagic (ehec) |
Responsible for bloody diarrhoea and hemorrhagic colitis. (Shiga- like toxin), but fever is not prominent and the bloody discharge are copious rather than scanty. A/E in the colon |
E. Coli |
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Definisi Enteroaggregative (eaec) |
Biofilm (small intestine + colon) causes chronic diarrhea and growth retardation in infant in developing countries |
E. Coli |
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A/E buat |
Attaching and effacing: ability to adhere to the intestinal mucose and destruct the brush border of microvili |
E. Coli |
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Site of infection epec |
Small bowel |
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Site of infection etec |
Smallbowel |
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Site of infection stec (shiga toxin producing e.coli) |
Large bowel |
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Site of infection enteroinvasiv e coli (eiec) |
Large bowel |
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Site of infection Enteroaggregative e.coli(eaec) |
Small bowel |
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Disease and clinical finding epec |
Infants diarrhea, watery diarrhea |
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Disease and clinical finding etec |
Travellers diarrhea and infant diarrhea |
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Disease and clinical finding stec |
Hemorrhagic colitis with hemolytic uremic syndrome |
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Disease and clinical finding eiec |
A disease very similar to shigellosis |
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Disease and clinical finding eaec |
Acute and chronic diarrhea in persons |
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Pathogenesis epec |
Attaching/effacing lesion |
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Pathogenesis etec |
Lt and st encoded by plasmid, adhesive factor |
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Pathogenesis stec |
Stx-I atau stx II encoded by phage. Attaching/effacing lesion |
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Pathogenesis eiec |
Virulence encoded on plasmid and chromosome |
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Pathogenesis eaec |
St-like toxin and a hemolysin |
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Spesies shigella (4) |
S. Flexneri, s. Boydii, s. Sonnei, s. Dysenteriae |
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Klinis shigella |
Bacillary dysentery atau shigellosis (bloody feces associated with intestinal pain) |
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Toxin shigella |
Shiga toxin (chromosomally-encoded) which is neurotoxic, enterotoxic, dan cytotoxic |
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Ciri shigella |
Nonspore, nonmotile, non lactose fermenting |
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Gejala shigella |
Usually develop about 1-7 Hari (biasanya 3 Hari) after you come in contact with the bacteria -Acute (sudden) abdominal pain or cramping -acute (sudden) fever -blood, mucus, or pus in stool -crampy rectal pain (tenesmus) -nausea and vomiting -watery diarrhea |
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Exam and test shigella |
-dehydration with fast heart rate and low blood pressure - abdominal tenderness - elevated white blood cell count - stool culture -white blood cells in stool |
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Morfologi e coli |
basil soliter |
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Flagella e. Coli |
flagella peritric |
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Antigen e. Coli |
antigen o, k, h, |
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Temperature optimum e coli |
optimum pada temperature 37, |
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E. Coli dapat memfermentasi |
ferment lactose, |
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Keaeroban e. Coli |
aerib dan fakultative anaerob, mikroaerofilik, hemolysis type B |
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Spore/ non spore e.coli? |
Non spore |
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Family apa e. Coli |
family enterobactericeae, |
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E coli indolnya bagaimana |
+ |
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Asetat e coli |
+ |
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Peragian laktosa e. Coli |
+ |
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Gas & glukosa e. Coli |
+ |
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Lisin dekarboksilase e. Coli |
(+/-) |
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Motilitas e. Coli |
(+/-) |
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Hemolisis tipe e. Coli |
B (+/-) |
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Ciri salmonella |
Gram negative rods |
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Antigen salmonella |
O, H, and Vi antigens |
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Kearoban salmonella |
Facultative anaerobic |
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Motile salmonella |
Motile (flagella peritic) |
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Fermentasi salmonella |
Glucose fermenting, non lactose fermenting |
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H2s salmonella |
+ |
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Extra or intra celluler pathogen salmonella? |
Intraceluller |
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Response acid salmonella |
Acid tolerant response |
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Salmonellosis slide pertama (1) |
-Enteric atau typhoid fever (primarily salmonella typhi and salmonella paratyphi) -enterocolitis (typically salmonella typhimurium, salmonella enteriditis, and salmonella Heidelberg) -other infection |
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Diagnosis salmonellosis |
Kultur tinja selama 2 Hari, tes aglutinasi:titer antibodi O Dan H (tes widal) pada minggu pertama setelah onset awal, kultur dan sumsum tulang |
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Helicobacter pylori Merupakan gram |
Bakteri gram negatif |
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Morfologi helicobacter pylori |
Helix shaped |
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Kearoban helicobacter pylori |
Microaerophilic |
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Flagella helicobacter pylori |
Lopotric (4-7) artinya motile |
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Spora helicobacter pylori |
- |
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Katalase helicobacter pylori |
+ |
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Oksidase helicobacter pylori |
+ |
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Urease helicobacter pylori |
+ |
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Transmission helicobacter pylori |
Fecal oral |
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Patogenitas helicobacter pylori |
Adhesi pada sel epitel gaster. Urease (urea > amonia) - neutralize acid vacuolizing cytotoxin (VacA) merusak sel epitel |
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Fungsi flagella helicobacter pylori |
Bacterial mobility & chemotaxis to colonize under mucosa |
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Fungsi urease helicobacter pylori |
Neutralize gastric acid, gastric mucosal injury (by ammonia) |
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Fungsi lipopolysaccharides helicobacter pylori |
Adhere to host cell inflammation |
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Fungsi type IV secretion system helicobacter pylori |
Pili like structure for injection of effectors |
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Fungsi secretory enzyme helicobacter pylori (...) |
(mucinase, protease, lipase) gastric mucosal injury |
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Fungsi Exotoxin helicobacter pylori (...) |
Vacuolating toxin (vacA) gastric mucosal injury |
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Test helicobacter pylori |
Fecal antigen test, urea breath test > carbon (urea), blood test (antibody), biopsi gaster > kultur, ditanam dalam media Kaya nutrisi dan selektif dgn kondisi microaerob (90% N2, 5% CO2, 5% O2) tiga sampai emat Hari. Identifikasi:adanya oxidase, katalase, Dan urease, endoscopy |
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Bakteri gram negative klo dicat jd warna |
Merah |
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Bakteri gram negative klo dicat jd warna |
Merah |
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Enterobacteriaceae motil kecuali |
Klebsiella, shigella |
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Yg Simon citrate + (3) |
Klebsiella, proteus, pseudomonas |
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Yg urea + (2) |
Proteus, klebsiella |
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Yg Simon citrate - |
Shigella salmonella e coli |
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Yg ureanya - |
Shigella, pseudomonas, salmonella, ecoli |
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