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51 Cards in this Set

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  • Back

What is the Human Endocrine System?

Made up of glands that transmit chemical messengers through the body

What are hormones?

Chemical messengers released in the blood that affects only one target cell

What is a gland?

Organ made of cells that secrete

What are the 2 types of glands?

- Exocrine glands


- Endocrine glands

What is an exocrine gland?

Secrete nonhormonal chemicals into ducts which transport chemicals to specific locations inside and outside the body. Eg sweat, mucous, salivary glands, pancreatic juice

What is an endocrine gland?

Ductless glands located throughout body - secretes hormones into bloodstream. Eg Pancreas - insulin, glucagon

What are the 2 types of hormones?

- Amino Based Hormones


- Steroid Hormones

What is Amino Based hormones?

Proteins, peptide, amino acids and other forms derived from amino acids. Eg Adrenaline

What is Steroid Hormones?

Lipids body makes from cholesterol. Eg oestrogen, testosterone

What does the hypothalamus do with regards to endocrine system?

Links the nervous system to the endocrine system

What does the Pituitary Gland do?

Secretes hormones that affect other glands and organs

How many hormones does the anterior and posterior pituitary gland secrete?

Anterior - 6


Posterior - 2

What does the Pituitary gland secrete?

2 amino acid based hormones:


- Oxytocin: released when 40 weeks pregnant, which stimulates uterus to contract during childbirth and stimulates milk let down reflex


- ADH: Anti-duiretic hormone which controls the amount of water absorbed into blood from kidneys

What hormones does the Anterior Pituitary gland secrete?

- Growth hormone: controls skeletal and muscular growth


- Prolactin: stimulates and sustains production of breast milk during lactation


- Thyroid Stimulating Hormone: controls release of thyroxine from thyroid


- Adrenocorticotrophic hormone: controls adrenal cortex


- Follicle Stimulating hormone: stimulates ovaries to produce eggs and testes to produce spermatogenesis


- Lutenising hormone: controls secretion of testosterone and progesterone

Where is the Thyroid gland located?

2 lobes located near lower part of larynx

What does the Thyroid gland secrete?

When simulated by TSH, thyroid produces and releases thyroxine

What does Thyroxine do?

Controls metabolism - rate of energy use


Controls metabolism - rate of energy use

What are the symptoms of hyperthyroidism?

- Weight loss


- High blood pressure


- High heart rate


- High body temperature

What are examples of hyperthyroidism?

- Goitre: swelling of thyroid


- Exophthalmia: bulging eyeballs


- Grave's disease

What are the symptoms of hypothyroidism?

- Growth redardation


- Exhaustion


- Weight gain


- Low heart rate


- Low body temp

What are examples of hypothyroidism?

- Cretinism: form of mental retardation during fetal and childhood development


- Myxodema: mental retardation on adults

Where are the adrenal glands located and what is their structure?

One adrenal gland is located above each kidney. Each had an inner core - medulla - and outer layer - cortex.

What controls the adrenal medulla?

Nervous system

What regulates adrenal cortex?

Anterior Pituitary

What hormone does the adrenal medulla secrete?

Adrenaline

What is the function of adrenal medulla?

Orchestrates nervous system's reaction to stress:


- Breathing increase


- Pupils dilate


- Heart beat increases


- Peristalsis slows down


- Liver converts more glucagon to glucose


- Blood pressure increases


- Muscles receive more blood

What does the adrenal cortex respond to?

Adrenocorticotrophic hormone

What causes the anterior pituitary gland to release ACTH?

Stress

What does ACTH stimulate the adrenal cortex to make?

Cortisol and Aldosterone

What does cortisol do?

Regulates metabolism of carbohydrates and proteins

What does aldosterone do?

Helps maintain salt-and-water balance in body by affecting kidneys

What is the hypersecretion of cortisol?

Cushing's Syndrome

What is the hyposecretion of cortisol?

Addison's disease

What do sex hormones do?

Regulates body changes that start with puberty

What is puberty?

Adolescent stage when sex organs mature and secondary sex characteristics appear

What occurs in females during puberty?

Menstrual cycle begins, breadth grow and hips widen

What occurs in males during puberty?

Sperm production begins, voice deepens, chest broadens, hair grows on body and face

What regulates female and male secondary sex characteristics?

Female - Estrogen


Male - Testosterone

What cells of the pancreas function together as endocrine gland?

Islets of Langerhans

What does the Islet of Langerhans cells secrete?

2 amino acid based hormones that regulate sugar levels in blood:


- Insulin


- Glucagon

What does insulin do?

Lowers body sugar level by stimulating body cells to absorb glucose and store as glycogen in liver

What does glucagon do?

Turns stored glycogen into glucose to release into bloodstream to raise glucose levels

What is an example of hyposecretion of insulin?

Diabetes:


- Type 1: childhood disorder, treated with daily injections of insulin or sometimes islet cell transplant


- Type 2: usually happens over 40 yrs old, more common, herditary, controlled through exercise and diet

What is an example of hypersecretion of insulin?

Hypoglemia: disorder where glucose is stored instead of being delivered to body cells

What is homeostasis?

The maintainance of relatively constant internal environment by automatic control mechanisms

How does the endocrine system maintain homeostasis?

Negative feedback mechanisms

What is the process of negative feedback?

When there is an increase from normal, a corrective mechanism will cause it to decrease and vice versa

What are the 3 example of negative feedback in endorcine system?

- Regulation of thyroxine


- Regulation of blood sugar levels


- Regulation of estrogen and progesterone

What is an example of hypersecretion of growth hormone?

- Giantism: children


- Acromegaly: adults

What is an example of hyposecretion of growth hormone?

Dwarfism

What are the differences between the nervous system and the endocrine system?

- ES made of glands whereas NS made of nerves


- ES produces hormones whereas NS produces nerve impulses


- ES transports hormones through blood whereas NS transmit impulses along the nerves