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26 Cards in this Set

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ADA Diagnostic Criteria for Type II Diabetes Mellitus

A1C >6.5 or


Fasting Plasma Glucose >126 or


2 hr plasma glucose >200 mg/dL or


random >200 mg/dL with symptoms of hyperglycemia

Disease where the pituitary gland makes to much ACTH- symptoms include round moon face and central obesity

Cushing's Disease

Top 3 causes of death >65 y/o

1. heart disease


2. cancers (lung, colorectal)


3. COPD

Middle aged woman, overweight complains of fatigue, weight gain, cold intolerance, constipation, mentral abnormalities, puffy face hands, and feet.


Labs: elevated TSH, decreased T4

Hashimoto's Thyroidistis




TSH elevated T4 decreased




treat with Synthroid

Mixed Insulin (Rapid + Long Acting) - duration time

16-24 hours





Mixed Insulin Types

Novolog Mix 70/30


Humalog Mix 75/25, 50/50


Humulin 70/30

Whipples Triad

Suggests Hypoglycemia


1. Symptoms after fasting or heavy exercise


2. Low plasma glucose measured at time of symptoms


3. relief of symptoms when glucose returned to normal

Fasting Triglycerides Values

Desireable: <150 mg/dL


Borderline high: 150-199 mg/dL


High: 200- 499 mg/dL


Very High: >500

Thyroid Values

Normal TSH 0.5- 4.5




Normal Serum Free T4 : 0.8- 1.8



ADA Diagnostic Criteria for Impaire1 Fasting Glucose

IFG 100-125 mg/dL constitutes pre-diabetes (must be checked on subsequent day)




2-h PH on the 75- g OGTT 140-199




A1C >5,7- 6.4

Initiating Basal Insulin Formula

Total insulin needs 1-12.2 u/kg/day - consider bedtime basal like NPH-


Start at 0.2 u/kg as bolus at bed




1kg x 0.2= _____ units daily



Initiating Synthroid for Primary Hypothyroidism

Adults need 1.6 mcg/kg/day


Start with full replacement dose in healthy, young patients




kg x 1.6 = _____ dose

With what lab values should you consider an insulin?

AIC >10


FG >250

Hyperthyroidism symptoms

fatigue


weight loss


heat intolerance


hyperhydrosis


fine, silk hair, alopecia


insomnia


muscle weakness


dyspnea


palpiations


hyperdefecation


mentral irregularity



metabolic abnormalities associated with hypothyroidism

hypercholesterolemia, elevated LDL


macrocytic anemia


increased CK


hyponatremia

Hypothydroism treatment in elderly

Patient 50-60 : start 50 mcg daily ; check TSH 4-6 weeks




Presence of cardiac disease: start at 25 mcg dail, check TSH 4-6 weeks




Increase every 3-6 weeks by 25 mcg until normal TSH levels

Two most common side effects of Metformin

Increased creatining


metabolic acidosis

Diabetes Mellitus risk factors

age >45


BMI >25


family hx


habitual physical inactivity


HTN 140/90


HDL <35, TRIG >250


women on PCOs


Hx vascular disease


delivery ofo macrosomic infant


African American, Hispanic, Native American, Asian, Pacific Islander


A1C >5.7

Hypothyroidism Symptoms

fatigue


weight gain


cold intolerance


skin dryness


hair dry, course


depression (elderly)


muscle cramps


edema


bradycardia


constipation

Immediate Insulin (Rapid Acting)




Onset of Action and Duration

OA: 15-30 minutes




Peak: 30- 2 1/2 hours




Duration 3-6 1/2 hours




Used by Type I diabetics before each meal


(Covers one meal at a time)




Examples: Novolog, Humalog, Apidra

Regular Insulin (Short Acting Insulin)




Onset of Action and Duration

OA: 30 minutes- 60 min


Peak 1-5 hours


Duration: 6-8 hours




Lasts from meal to meal


Examples: Humulin R, Novolin

Long Acting Insulin (NPH)


Onset of Action and Duration

OA: 1 hour


D: 24 hours


Lasts from breakfast to dinner




Example: Lantus, Levemer

Elderly adult who complains of bone pain with generalized weakness. Pain located on chest an back with generalized weakness. Pain located on chest and back. Anemia present.

Multiple Myeloma




Labs for cancerous mestasis of bone: increased serum calcium, increased alkaline phosphate

Middle aged female loses a large amount of weight rapidly, becomes irritable, anxious and hyperacitive. She has insomnia with frequent bowel movements, amenorrhea and heat intolerance. Exam reveals large thyroid present.

Graves Disease




look for very low TSH ( <0.01) + elevated free T4

Autoimmune disorder that leads to over activity of the thyroid gland (hyperthyroidism)

Graves Disease

Hyper/hypo glycemia mneumonic

Hot and dry sugar high; cold and clammy, need so candy