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39 Cards in this Set
- Front
- Back
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Adrenal cortex derived from? |
Mesoderm |
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Adrenal medulla derived from? |
Neural crest |
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Primary regulation of Zona Glomerulosa |
Renin-Angiotensin |
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Primary regulation of Zona Fasciculata |
ACTH & Hypothalamic CRH |
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Primary regulation of Zona Reticularis |
ACTH & Hypothalamic CRH |
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Secretory products of the Zona Glomerulosa |
Aldosterone (Mineralocorticoids) |
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Secretory products of the Zona Fasciculata |
Cortisol (Glucocorticoids) |
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Secretory products of the Zona Reticularis |
Sex hormones (Androgens) |
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Secretory products of the Medulla |
NE, Epi (catecholamines) |
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RIGHT adrenal drainage |
Right adrenal-> right adrenal vein-> IVC |
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LEFT adrenal drainage |
Left adrenal-> left adrenal vein-> left renal vein-> IVC |
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Posterior pituitary gland produces |
- ADH
- oxytocin |
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Anterior pituitary gland produces |
- FSH - LH - ACTH - TSH - GH - Prolactin |
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Posterior pituitary gland derived from |
neuroectoderm |
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Anterior pituitary gland derived from |
ectoderm (Ranke's pouch) |
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Hormones made in the Acidophils |
- GH
- Prolactin |
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Hormones made in the Basophils |
- FSH - LH - ACTH - TSH |
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Endocrine pancreas cell type -ALPHA-
Location: ? Product: ? |
- peripheral
- glucagon |
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Endocrine pancreas cell type -BETA-
Location: ? Product: ? |
- central
- insulin |
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Endocrine pancreas cell type -DELTA-
Location: ? Product: ? |
- interspersed (few)
- somatostatin |
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Not present with exgenous insulin intake |
C-peptide |
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Anabolic effects of insulin |
INCREASE - glucose transport - glycogen synthesis and storage - triglyceride synthesis and storage - NA+ retention (kidneys) - protein synthesis - cellular uptake of K+ and amino acids |
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These don't need insulin for glucose uptake |
(BRICK L) - Brain - RBCs - Intestines - Cornea - Kidneys - Liver |
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GLUT-1 transport found on |
- Brain
- RBCs |
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GLUT-4 (dependent) transport found on |
- Skeletal muscle
- Adipose tissue |
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Hypothalamic-pitutary hormone regulation
- TRH |
(+) TSH and prolactin |
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Hypothalamic-pitutary hormone regulation
- Dopamine |
(-) prolactin |
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Hypothalamic-pitutary hormone regulation
- CRH |
(+) ACTH |
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Hypothalamic-pitutary hormone regulation
- GHRH |
(+) GH |
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Hypothalamic-pitutary hormone regulation
- Somatostatin |
(-) GH, TSH (really everything) |
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Hypothalamic-pitutary hormone regulation
- GnRH |
(+) FSH, LH |
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Hypothalamic-pitutary hormone regulation
- Prolactin |
(-) GnRH |
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Dopamine agonists that inhibits prolaction secretion and can be used in the Rx of prolactinmoa |
- Bromocriptine |
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Dopamine antagonists that stimulate proctin secretion |
- most antipsychotics
- estrogens (OCPs and pregnancy) |
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Cortisol functions |
- maintains blood pressure (upregulates alpha-1) - decrease bone formation - anti-inflammatory - decrease immune function - increase gluconeogenesis, lipoplysis |
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Source of PTH |
- Parathyroid Chief cells |
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PTH function |
- increase bone resorption of calcium & phosphate
- increased kidney reabsorption of calcium in distal convoluted tubule
- decrease reabsorption of phosphate
- increase 1,25 OH vit D production by stimulating kidney 1alpha-hydroxylase |
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PTH regulation |
free Ca+ ions |
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Common causes of decreased Mg2+ |
- Diarrhea - aminoglycosides - diuretics - alcohol abuse |
