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14 Cards in this Set

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Fentanyl

MOA: opioid agonist —> analgesia + sedative effects


Dose: 25-100 mcg IV q 1-2 hourly


EM indications: pain control, sedation adjunct


Pitfalls: respiratory depression, vasodilation (hypotension), laryngospasm, preg C

Furosemide (Lasix)

MOA: inhibits Na and Cl réabsorption in the ascending LOH and distal convoluted tubule


Dose: 20-40mg IV, reassess, increase to desired effect, max single dose = 200mg


EM indications: pulmonary oedema, CHF exacerbation, hyperkalaemia (if making urine)


Pitfalls: volume depletion, hypokalemia, metabolic alkalosis, ototoxicity, preg C

Ketamine (Ketelar)

MOA: acts on cortex and limbic system, NMDA receptor antagonist


Dose: subdissociative 0.1-0.5 mg/kg IV Procedural sedation 0.5-1 mg/kg IV RSIinduction 2mg/kg IV


EM indications: analgesia, sedation, RSI (rapid sequence induction)


Pitfalls: emergence reactions (treat with benzos, barbs), laryngospasm, IOP increase, ICP increase, tachycardia, HTN, preg D

Furosemide (Lasix)

MOA: inhibits Na and Cl réabsorption in the ascending LOH and distal convoluted tubule


Dose: 20-40mg IV, reassess, increase to desired effect, max single dose = 200mg


EM indications: pulmonary oedema, CHF exacerbation, hyperkalaemia (if making urine)


Pitfalls: volume depletion, hypokalemia, metabolic alkalosis, ototoxicity, preg C

Diazepam (Valium)

Drug class: benzodiazepine


MOA: enhances inhibitory effects of GABA


Dose: 2-10mg PO/IV/IM q 6 hours PRN


EM indications: seizure abnormality, alcohol withdrawal, agitation, muscle spasm


Pitfalls: respiratory depression, hypotension, preg D

Lorazepam (Ativan)

Drug class: benzodiazepine


MOA: enhances inhibitory effects of GABA


Dose: usual bolus dose = 1-2 mg IV, usual continuous infusion = 1-10mg/hr


EM indications: delirium tremens, status epilepticus, serotonin syndrome, agitation


Pitfalls: respiratory depression, hypotension, preg D

Magnesium sulfate

MOA: participates in physiologic process


Dose: eclampsia = 2-4 grams IV over 5 min, pulseless torsades = 2 grams IV push, asthma exacerbation= 2 grams IV over 5 min


EM indications: torsades, ventricular dysrhythmias, eclampsia, status asthmaticus


Pitfalls: respiratory depression, hypotension, preg A

Methylprednisolone - SoluMedrol

MOA: multiple glucocorticoid and mineralocorticoid effects —> regulates BP, electrolyte balance, physiologic stress response, reduces inflammation and inhibits immune system


Dose: asthma = 1mg/kg IV, hypersensitivity reaction = 1mg/kg IV


EM indications: severe asthma, acute hypersensitivity reaction


Pitfalls: immunosuppression, preg C


Methylprednisolone (Depo-medrone) + lidocaine 1% suspension for injection

MOA: anti inflammatory + analgesia


Dose: Depo medrol = 40mg/ml, small joint= 0.1-0.25ml, medium joint= 0.25-1ml, large joint 0.5-2ml.


Eg at SJRH I performed inj on trochanteric bursitis= 1ml (40mg) + 3ml


EM indications: intraarticular (RA, OA), periarticular (epicondylitis), intrabursal (subacromial, prepatellar, olecranon) and tendon sheath (tendinitis)


Pitfalls: pull back on syringe to look for synovial fluid/ blood, move joint / area slightly to aid mixing, advise to return if signs of infection

Metoclopramide (Reglan IV, Maxolon PO)

MOA: antagonises dopamine receptors in the chemoreceptor trigger zone


Dose: 10mg IV q 6 hours PRN


EM indications: vomiting prévention and treatment


Pitfalls: tardive dyskinesia, extrapyramidal sx, dystonia, methemoglobinema, preg B

Morphine sulfate

MOA: opioid agonist analgesia with adjunctive sedative effects


Dose: 2-10mg IV q 2-6 hours PRN; recommended dose 0.1mg/kg IV


EM indications: pain control


Pitfalls: respiratory depression, vasodilation (hypotension), preg C

Ondansetron (Zofran)

MOA: antagonises serotonin 5-HT3 receptor, centrally acting antiemetic


Dose: 4-8mg IV q 4-6 hourly PRN


EM indications: vomiting prévention and treatment


Pitfalls: QT prolongation, torsades (rare), preg B

Propofol (Diprivan)

MOA: GABA agonist, Na channel blocker


Dose: procedural sedation = 1mg/kg IV bolus then 0.5mg/kg q 3 minutes to effect RSI induction = 1.5-2.5 mg/kg IV x1


EM indications: procedural sedation, RSI induction, ventilator sedation


Pitfalls: hypotension, anaphylaxis, bradycardia, apnea, preg B

Dobutamine


Dopamine

Drug class: sympathomimetics


MOA: mimic agonist actions of E and NE


Indication: short term hemodynamic support guided by continuous monitoring. Severe refractory HF with low CO despite adequate treatment.


Pearls: Need continuous monitoring of arterial and venous pressure + ECG