Eeb 181 Malaria Vocabulary

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Sporozoite

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The infective state passed in saliva of the mosquito and formed inside an oocyst by the process of sporogony

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schizont

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Stage undergoing asexual division by multiple fission or segmentation.

May be found in liver cells (pre-erythrocytic schizonts) or in the erythrocytes (erythrocytic schizonts). Nuclear divisions have occured; cytokinesis has not.

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Segmenter

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A schizont in which cytokinesis has been completed

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Merozoite

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The product of division by schizogony.

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Trophozoite

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Stage of the asexual form with an undivided nucleus, seen in erythrocytes and liver cells

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Hypnozoite

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aka cryptozoite, a dormant (pre or exo)erythrocytic merozoite

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Microgametocyte

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male gametocyte, produces microgametes

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exflagellation

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process by which microgametes are formed from a microgametocyte

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Macrogametocyte

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female gametocyte, produces a single macrogamete

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Zygote

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fertilized ovum

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Ookinete

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motile stage of the zygote that precedes the oocyst stage

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Sporogony

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sexual phase in the life cycle of some protozoans. In _Plasmodium_, this takes place in the mosquito vector

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Schuffner's dots

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Pinkish small and round stippling seen on red cells infected with P. vivax (in Giemsa-stained films)

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Maurer's dots

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Coarse, irregular stippling seen on red cells infected with P. vivax (in Giemsa-stained films)

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Incubation period

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interval between entry of sporozoites and the first clinical manifestation

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pre-patent period

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minimum time between the entry of sporozoites and the first appearance of parasites in red cells

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Latency

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duration between primary attack of malaria and the relapses. There are no parasites in the circulation during this period

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Relapse

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Renewed manifestation of infection due to the invasion of blood by merozoites form the pre-erythrocytic stage

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Re-infection

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Renewed manifestation of infection not due to the original infection, but resulting from subsequent fresh infection.