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14 Cards in this Set
- Front
- Back
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the coupling of electron transport to the formation of ATP in the mitochondria is known as ___
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oxidative phosphorylation
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what is the source of energy that drives ATP formation in oxidative phosphorylation
what is the name of the theory that describes this process? |
proton gradient across the inner mitochondrial membrane
chemiosmotic theory |
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what limits the degree to which oxidative phosphorylation takes place in the cell
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the amount of ADP and oxygen present in the cell
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what type of tissue in mammals provides a mechanism for the uncoupling of oxidation and phosphorylation?
relatively high levels found in newborns electron transport continues even when there is plenty of ATP present |
brown fat
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what is the purpose of the uncoupling mechanism of brown fat?
what protein is responsible for this mechanism? |
it generates excess heat, which helps to keep newborns warm
thermogenin |
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single base change of an Arg to His in the mitochondrial gene ND4
deformation of complex I of the electron transport chain results in bilateral loss of vision in early adulthood |
Leber's hereditary optic neuropathy
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products of the pentose phosphate pathway
what are they used for? |
riboses needed for synthesis of DNA and RNA
NADPH needed for biosynthesis of molecules, detoxification and excretion in the liver, and reduction of glutathione in RBCs |
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key enzyme in the pentose phosphate pathway
what stage of the pathway does it stimulate? |
G6PD
oxidative stage |
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what ratio effects G6PD activity?
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NADP/NADPH ratio
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inheritance pattern for G6PD deficiency
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X-linked recessive
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products of the pentose phosphate pathway
what are they used for? |
riboses needed for synthesis of DNA and RNA
NADPH needed for biosynthesis of molecules, detoxification and excretion in the liver, and reduction of glutathione in RBCs |
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key enzyme in the pentose phosphate pathway
what stage of the pathway does it stimulate? |
G6PD
oxidative stage |
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what ratio effects G6PD activity?
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NADP/NADPH ratio
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inheritance pattern for G6PD deficiency
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X-linked recessive
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