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17 Cards in this Set
- Front
- Back
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distinct cell masses that make up the endocrine component of the pancreas
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islets of Langerhans
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two main exocrine pancreatic cells
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pancreatic acinar cells and centroacinar cells
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pyramidal, enzyme secreting cells arranged around a central lumen in the pancreas
what do these cells produce? |
pancreatic acinar cells
proteases, lipases, amylase, ribonucleases and deoxyribonucleases |
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enzymes are stored inside pancreatic acinar cells as ___
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zymogen granules
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what stimulates the release of enzymes from pancreatic acinar cells?
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cholecystoknin or parasympathetic stimulation
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exocrine pancreatic cells that have clear cytoplasm and a condensed nucleus
where are they found? |
centroacinar cells
at the origin of the intercalated duct |
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what is produced by centroacinar cells?
what stimulates its production? |
bicarbonate-rich fluid
secretin |
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cells that release glucagon, and the processes stimulated by its release
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alpha cells
gluconeogenesis and glycogenolysis |
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cells that release insulin, and the processes stimulated by its release
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beta cells
glycogen synthesis and triglyceride synthesis |
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the most numerous pancreatic endocrine cells
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beta cells
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cells that produce somatostatin in the pancreas
what is the function of somatostatin? |
delta cells
inhibits release of insulin and glucagon |
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cells that release vasoactive intestinal peptide in the pancreas
what are it's functions? |
D-1 cells
similar effects to glucagon, also affects secretory activity in the gut and stimulates exocrine secretion |
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cells that produce pancreatic peptide in the pancreas
what is it's function? |
PP (F) cells
inhibits exocrine secretion (shuts the place down in between meals) |
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function of gastrin
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stimulates gastric HCl secretions
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4 minor pancreatic endocrine hormones (functions are mainly paracrine)
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somatostatin
vasoactive intestinal peptide (VIP) pancreatic peptide gastrin |
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effect of parasympathetic stimulation on the pancreas
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increase in insulin and glucagon
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effect of sympathetic stimulation on the pancreas
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inhibition of insulin
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