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35 Cards in this Set

  • Front
  • Back
M1 (Gq) - Brain
memory formation, cognitive functioning
M2 (Gi) - Heart
dec HR and dec atrial contraction
M3 (Gq) - Lung
Bronchiconstriction
M3 (Gq) - Bladder
Detrusor contraction
M3 (Gq) - Eyes
Pupillary sphincter muscle contraction (miosis), ciliary muscle contraction (accomodation)
M3 (Gq) - GI
Inc peristalsis, inc salivary and gastric secretions
M3 (Gq) - skin
Inc Sweat production
A1 ( Gq) - Vascular Smooth Muscle
constricts blood vessels in skin
A1 ( Gq) - GI/bladder
constricts sphincters
A1 (Gq) - Eyes
Dilates pupil
A1(Gq) - Heart
Inc BP, reflexive dec HR
A2 (Gi) - GI
Dec motility
A2 (Gi) - Bladder
Relaxes bladder wall
A2 (Gi)
Dec symp outflow, Dec insulin release,Dec lipolysis, Inc platelet aggregation
Bi (Gs) - Heart
Inc HR, Inc Contractility, inc AV node condution
B1 (Gs) - Kidney
Inc renin release
Bi (Gs) - Fat cells
Inc lipolysis,
B2 (Gs) - Vasc SM
dilates blood vessles in skeletal m.
B2 (Gs) - GI
dec motility
B2 (Gs) - Bronchioles
dilates bronchiolar SM
B2 (Gs) - bladder
relaxes bladder wall
B2 (Gs) - uterus
Dec uterine tone
B2 (Gs) - Other
Inc HR, Inc Contractility, Inc lipolysis, inc insulin resistance
B2 (Gs) - eye
Ciliary muscle relaxation, inc aquemous humor production
D1 (Gs)
relaxes renal vasc SM (improve RBF)
D2 (Gi)
Modulates NT release in brain
H1 (Gq)
Inc nasal and bronchial mucous production, contraction of bronchioles, pruritis, and pain
H2 (Gs)
Inc gastric acid secretion
V1 (Gq)
Inc vasc SM contraction
V1 (Gs)
Inc H20 perm and reabsroption in collecting tubules of kidey
Gq
H1, A1, V1, M1, M3 (HAVe 1M&M)
Gs
B1, B2, D1, H2, V2
Gi
M2, A2, D2 (MAD 2s)
Gq
Phospholipase C > Lipids > DAG (Protein kinase A) + IP3 (Inc Ca intracellular)

Smooth muscle contraction
Gs
Adenylyl cyclase > ATP --> camp >> Protiein kinase A >> Inc CA in heart, inc vasodil of vasc SM

INHIBITS myosin light chain kinase of smooth muscle.