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35 Cards in this Set
- Front
- Back
M1 (Gq) - Brain
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memory formation, cognitive functioning
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M2 (Gi) - Heart
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dec HR and dec atrial contraction
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M3 (Gq) - Lung
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Bronchiconstriction
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M3 (Gq) - Bladder
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Detrusor contraction
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M3 (Gq) - Eyes
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Pupillary sphincter muscle contraction (miosis), ciliary muscle contraction (accomodation)
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M3 (Gq) - GI
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Inc peristalsis, inc salivary and gastric secretions
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M3 (Gq) - skin
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Inc Sweat production
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A1 ( Gq) - Vascular Smooth Muscle
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constricts blood vessels in skin
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A1 ( Gq) - GI/bladder
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constricts sphincters
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A1 (Gq) - Eyes
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Dilates pupil
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A1(Gq) - Heart
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Inc BP, reflexive dec HR
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A2 (Gi) - GI
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Dec motility
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A2 (Gi) - Bladder
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Relaxes bladder wall
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A2 (Gi)
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Dec symp outflow, Dec insulin release,Dec lipolysis, Inc platelet aggregation
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Bi (Gs) - Heart
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Inc HR, Inc Contractility, inc AV node condution
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B1 (Gs) - Kidney
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Inc renin release
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Bi (Gs) - Fat cells
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Inc lipolysis,
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B2 (Gs) - Vasc SM
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dilates blood vessles in skeletal m.
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B2 (Gs) - GI
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dec motility
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B2 (Gs) - Bronchioles
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dilates bronchiolar SM
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B2 (Gs) - bladder
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relaxes bladder wall
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B2 (Gs) - uterus
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Dec uterine tone
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B2 (Gs) - Other
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Inc HR, Inc Contractility, Inc lipolysis, inc insulin resistance
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B2 (Gs) - eye
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Ciliary muscle relaxation, inc aquemous humor production
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D1 (Gs)
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relaxes renal vasc SM (improve RBF)
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D2 (Gi)
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Modulates NT release in brain
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H1 (Gq)
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Inc nasal and bronchial mucous production, contraction of bronchioles, pruritis, and pain
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H2 (Gs)
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Inc gastric acid secretion
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V1 (Gq)
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Inc vasc SM contraction
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V1 (Gs)
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Inc H20 perm and reabsroption in collecting tubules of kidey
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Gq
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H1, A1, V1, M1, M3 (HAVe 1M&M)
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Gs
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B1, B2, D1, H2, V2
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Gi
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M2, A2, D2 (MAD 2s)
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Gq
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Phospholipase C > Lipids > DAG (Protein kinase A) + IP3 (Inc Ca intracellular)
Smooth muscle contraction |
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Gs
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Adenylyl cyclase > ATP --> camp >> Protiein kinase A >> Inc CA in heart, inc vasodil of vasc SM
INHIBITS myosin light chain kinase of smooth muscle. |