Drug Therapy For Asthma

Front 1

what is a bronchodilator?

Back 1

adrenergics: names:albuterol (provetil, ventolin), bitolterol (tornalate), terbutaline (brethaire) action: bind to beta2 receptors of the bronchi; dialates bronchioles
interventions: can cause tachycardia from excessive use, pt has to inhale med. contraindicated use in cardiac pts.

Front 2

What are Xanthines?

Back 2

short acting theophylline (aminophylline),action: bronchodilation, decreases vascular permeability, stregthens contractions of diaphragm,increases CO, peripheral vasodilation, stimulates CNS, intervention: monitor serum drug levels closley,use cautiously in cardiac pts, peptic ulcers, and acute gastritis.

Front 3

what are corticosteriods?

Back 3

anti inflammatory agents, prednisolone (cotolone), prednisone, inhalers: budesonide, fluticasone, action: suppress inflammation, and increases sensiblity of Beta2 receptors improving actions of bronchiodilators, Interventions: adm. before bronchiodilators, use cautiously in pts with CHF, peptic ulcers, thrombolitic disease

Front 4

what are anticholinergics?

Back 4

Ipratropium (atrovent), action: block the action of acetylocholine in bronchial muscle, intervention: taken by inhalation, use cautiously in pts in narrow angle glaucoma, prostatic hypertrophy.

Front 5

what are leukotriene antagonists?

Back 5

Zileuton(Zyflo) action: prevent leufotriene synthesis, Zafirlukast(Accolate) Montelukast (singular), action: block the leukotriene receptor; Strong mediators of bronchoconstriction and imflammation, increase mucous secretions and mucosal edema, Interventions: contraindicated use in pts with liver disease, monitor hepatic enzyme levels and discontinue if 5x above norms.

Front 6

what are mast cell stabilizers?

Back 6

cromolyn sodium(Intal), action: stablilize mast cells, and prevent the release of bronchoconstrictive and inflammatory substances. Interventions: used cautiously in pts with impaired renal or hepatic function.