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30 Cards in this Set
- Front
- Back
- 3rd side (hint)
atropine
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muscarinic receptor antagonist
blocks all subtypes Pharmacological effects -papillary dilation -cycloplegia -reduces GI secretions and motility -decreases sweating -mild tachycardia |
similar to scopolamine
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scopolamine
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Similar to atropine-exerts more CNS action
Effects -drowsiness -amnesia |
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ipratropium
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competitive muscarinic agonist
administered by inhalation in reversible airway disease where bronchial restriction has resulted from PNS |
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nicotine
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Depolarizing (noncompetitive) ganglionic blocker
initially activate nicotinic Ach receptors to cause depolarization of neural membrane if too much nicotine membrane is unable to repolarize and no longer responds to Ach release |
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trimethaphan
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Nondepolarizing nicotinic(competitive) ganlionic blocking drug
competes with ACh at nicotinic receptor and prevents depolarization of postsynaptic membrane |
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D-tubocurarine
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Neuromuscular nondepolarizing blocking agent
block Ach receptors at motor end plate - paralyzes skeletal muscle |
contains "cur" think about curare
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atracurium
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Neuromuscular nondepolarizing blocking agent
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vecuronium
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Neuromuscular nondepolarizing blocking agent
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mivacurium
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Neuromuscular nondepolarizing blocking agent
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succinylcholine
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muscarinic agonist (depolarizing blocker)
persistent depolarization of the motor end plate |
just like acetylcholine
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epinephrine
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adrenergic receptor agonist
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phenylephrine
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alpha-1 agonist
vasoconstrictor |
think about epin"ephrine"
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clonidine
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alpha-2 agonist
-antihypertensive drug decreases the sympathetic outflow from the medulla to the resistance vessels -also decreases addiction |
antihypertensive
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dipivefrin
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beta-2 agonist
-increases outflow of aqueous humor alpha-1 agonist -decreases formation of aqueous humor |
"di" it does two things
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isoproterenol
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beta receptor agonist
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albuterol
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selective beta-2 agonist
bronchodilator |
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salmeterol
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selective beta-2 agonist
-relaxes bronchial smooth muscle |
"rol" albute"rol"
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dobutamine
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beta-1 agonist
increases CO without increasing peripheral resistance |
sounds like dopamine
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dopamine
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weak beta-1 agonist
increases CO without increasing peripheral resistance |
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bethanechol
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selective muscarinic cholinergic receptor agonist
-long duration of action -used to increase tone and contractions of intestine and urinary bladder |
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pilocarpine
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primarily muscarinic receptor agonist
-not substrate for cholinesterases (long duration of action) |
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edrophonium
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reversible cholinesterase inhibitor
-short duration of action -used as test for myasthenia gravis |
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neostigmine
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reversible cholinesterase inhibitor
-longer duration of action -does not significantly enter blood brain barrier |
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DFP
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irreversible cholinesterase inhibitor
-long duration -used in eye to treat glaucoma |
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pralidoxine
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Acetylcholinesterase regenerator
- if administered soon after exposure to organophosphate |
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Acetazolamide
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Promixal tubule
carbonic anhydrase inhibitor decreaes Na/H exchange |
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Furosemide
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Loop of Henle
decreases Na/K/2Cl transporter promotes less Na reabsorption and increase K excretion |
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Thiazide
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Distal tubule
decrease Na/Cl cotransporter |
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Amiloride
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Distal tubule and collecting duct
decrease ENaC |
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Spironolactone
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MR antagonist
decrease ENaC |
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