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104 Cards in this Set

  • Front
  • Back
ACE inhibitors
prevent the synthesis of angiotensin II
potent vasoconstrictor
used to treat hypertension, HF, kidney disease
Acetylcholinesterase inhibitors
promote the accumulation of acetylcholine, resulting in prolonged cholinergic effects
Adrenergic
produce effects similar to neurotransmitter norepinephrine
Adrenergic blocking agents
inhibit the adrenergic system preventing stimulation of the adrenergic receptors
Aldosterone receptor antagonists
block stimulation of mineralocorticoid receptors by aldosterone, thus reducing high blood pressure by preventing sodium reabsorption
Aminoglycosides
Gentamicin, tobramycin, and related antibiotics particular effective against gram-negative microorganisms noted for potentially dangerous nephrotoxicity and ototoxicity
Amylinomimetic agent
used to reduce elevated postprandial hyperglycemia in pt with type 1 or 2 diabetes mellitus
Analgesics
Narcotic and nonnarcotic relieve pain without producing loss of consciousness or reflex activity
Androgens
These steroid hormones produce masculinizing effect
Anesthetics
for example, local anesthesia, general anesthesia, cause loss of sensation with or without a loss of consciousness
Angiotensin II receptor antagonists
Also known as ARBs act by binding to angiotensin II receptors sites preventing angiotensin II from binding to receptor site in vascular smooth muscle , brain, heart, kidneys, and adrenal gland, thus blocking the blood pressure elevating and sodium-retaining effects of Angiotensin II
Antacids
reduce the acidity of the gastric contents
antianginals
used to prevent or treat attacks of angina pectoris most common is nitroglycerin
antianxiety
used to treat anxiety symptoms or disorders also known as minor tranquilizers or anxiolytics although the term tranquilizer is avoided today to prevent the misperception that the pt is being tranquilized
Antibiotics
used to treat infections caused by pathogenic microbes the term is often used interchangeably with antimicrobial agents
Anticholinergics
block the action of acetylcholine in the parasympathetic nervous system also known as cholinergic blocking agents, antispasmodics, and parasympatholytic agents
Anticoagulants
prevent the formation enlargement or extension of blood clots. do not dissolve existing bloodclots
Anticonvulsants
suppress abnormal neuronal activity in the CNS preventing seizures
Antidepressants
Relieve depression
Antidiabetics
includes insulin and amylinomimetic agent used to treat type 1 diabetes mellitus. The secretogogues and those following are used to treat type 2 DM. Secretogogues, biguanide, thiazolidinediones, alpha-glucosidas inhibitors, amylinomimetic agent, and incretin-based therapy, used in the treatment of type 2 diabetes mellitus
Antidiarrheals
relieve or control the symptoms of acute or chronic diarrhea
Antidysrhythmics
used to correct cardiac dysrhythmias ( any heart rate or rhythm other than normal sinus rhythm
Antiemetics
used to prevent or treat nausea and vomiting
Antifungals
Used to treat fungal infections
Antiglaucoma
Used to reduce intraocular pressure
Antigout
used to treat active gout attacks or to prevent future attacks
Antihistamines
used to treat allergy symptoms may also be used to treat motion sickness, insomnia, and other nonallergic reactions
Antihypertensives
used to treat elevated blood pressure (hypertension)
Antilipemics
used to reduce serum cholesterol and or triglycerides most common are statins
Antimicrobials
Chemical that eliminate living microorganisms pathogenic to the pt also called antibiotics or antiinfectives
Antineioplastics
also called chemotherapy agents, used alone or in combination with other treatment modalities such as radiation surgery or biologic response modifiers to treat cancer
Antiparkinsons
used in treatment of Parkinsons syndrome and other dyskinesias
Antiplateltes
Prevent platelet clumping (aggregation) thereby preventing an essential step in formation of a blood clot, most common are aspirin, clopidogrel and prasugrel
Antipsychotics
used to treat severe mental illnesses also know as major tranquilizer or neuroleptics, although the term tranquilizer is avoided today to prevent the misperception that the patient is being tranquilized
Antipyretics
used to reduce fevers associated with a variety of conditions, most common are aspirin acetaminophen, and ibuprofen
Antispasmodics
actually anticholinergic agents
Antithyroid
used to treat the symptoms of hyperthyroidism, also known as thyroid hormone antagonists propylthiouracil, methimazole
antituberculins
used to prevent or treat an infection caused by Mycobacterium tuberculosis
Antitussive
used to suppress a cough by acting on the cough center of the brain
Antiulcer agents
these drugs such as histamine antagonsits decrease the volume and increase the PH of gastic secretions
Antivirals
used to treat infections caused by pathogenic viruses
betablockers
inhibit the activity of sympathetic transmitters norepinephrine and epinephring used to treat angina, dysrhythmias, hypertension, and glaucoma
bronchodiolators
stimulate receptors within the tracheobronchial tree to relax and dilate the airway passages allowing a greater volume of air to be exchanged and improving oxygenation
calcium channel blockers
also called calcium ion antagonsits slow channel blockers or calcium ion influx inhibitors inhibit the movement of calcium ions across the cell membrane used to decrease dysrhythmias slow rate of contractions of the heart and cause vasodilation
carbapenems
antibiotcs with a broad spectrum of activity against gram-positive and gram-negative bacteria, they act by inhibiting cell wall synthesis
Carbonic anhydrase inhibitors
interfere with the production of aqueous humor thereby reducing intraocular pressure associated with glaucom
Cell-stimulating agent
improve immune fn by stimulating the activity of various immune cells cholinergic: also known as parasympathomimetics produce effects similar to those of acetylcholine
Cholinesterase inhibitors
cholinesterase enzymes destroy acetylcholine stopping its action. Cholinesterase inhibitors block destruction of acetylcholine, thus prolonging its action examples of cholinesterase inhibitors are demecarium and echothiophate
coating agent
this drug sucralfate forms a complex that adheres to the crater of an ulcer protecting it from aggravation from gastric secretions
Colony-stimulating factors
stimulate progenitor cells in bone marrow to increase numbers of leukocytes thereby improving immune fn
corticosteroids
these hormones are secreted by the adrenal cortex of the adrenal gland
cycloplegics
anticholinergic agents that paralyze accommodation of the iris of the eye
cytotoxics
agents that cause direct cell death often used for cancer therapy
decongestants
reduce swelling in the nasal passages caused by a common cold or allergic rhinitis usually by vasoconstriction
Digestants
combination products containing digestive enzymes used to treat various digestive disorders and to supplement deficiencies of natural digestive enzymes
Digitalis glycosides
a class of drugs also known as cardiac glycosides that increase the force of contraction and slow the heart rate, thereby improving cardiac output, digoxin is the prototype
Diuretics
act to increase the flow of urine
Emetics
used to induce vomiting
Estrogens
steroids that cause feminizing effects
Expectorants
liquefying mucus by stimulating the natural lubricant fludis the bronchial glands allowing the liquefied mucus to be expectorated or coughed up out of the bronchi and trachea
Fluoroquinolones
Ciprofloxacin and related agents widely used broad-spectrum antibiotics
Gastric Stimulants
used to increase stomach contractions relax the pyloric valve and increase peristalsis in the gastrointestinal tract result in a decrease in gastric transit time and more rapid emptying of the intestinal tract prototype is metoclopramide
Glucocorticoids
also known as adrenocorticosteroids are used to regulate carbohydrate fat and protein metabolism
Gonadal hormones
hormones produced by the testes in the male and ovaries in the female
Herbals
plant products usually sold as food supplements may have pharmacologic effects that are not evaluated or regulated by the FDA
Histamine antagonists
decrease the volume and increase the pH of gastric secretions both during the day and the night
HMG-CoA reductase enzyme inhibitors
also known as the statins antilipemic agents that inhibit hydroxymethyl-glutaryl coenzyme A reductase enzyme the enzyme that stimulates the conversion of HMG-CoA to mevalonic acid, a precursor in the biosynthesis of cholesterol thus reducing the potential for atherosclerosis
Hyperuricemics
used to decrease the production or increase the excreation of uric acid excretion of uric acid thus lowering serum uric acid levels to prevent gout
hypnotics
used to produce sleep
incretin-mimetics
used to reduce basal glucose concentrations and elevated postprandial glucose concentrations used to treat diabetes mellitus
insulins
Hormone required for glucose transport into the cells for energy
Lactation suppressants
used to prevent physiologic lactation
laxatives
act by variety of mechanisms to treat constipation low molecular wt heparins, derivative of heparin anticoagulants for prophylactic treatment of venous thromboembolisms macrolides: Erythromycin, azithromycin, and related antibiotics
MAO inhibitors
agents that block monoamine oxidase, there by preventing the degradation and prolonging the action of norepinephrine and serotonin
Mineralocorticoids
steroids that cause the kidneys to retain sodium and water such as fludrocortisone, miotics: cause constriction of the iris
Mucolytics
reduced the thickness and stickiness of pulmonary secretions by acting directly on the mucous plugs to dissolve them
Muscle relaxants
relieve muscle spasms
mydriatics
cause dilation of the iris
Neurokinin-1 receptor antagonist
aprepitant is the first NK1 antagonist available blocks the effects of substance P on NK1 receptors. Used to prevent acute and delayed chemotherapy-related nausea and vomiting caused by highly emetogenic antineoplastic agents
Neuromuscular blockers
skeletal muscle relaxants used to produce muscle relaxation during anesthesia, reduce the use and side effects of general anesthetics, used to ease endotracheal intubation and prevent laryngospasm nitrates. Metabolize to nitric oxide a potent vasodilator used to treat angina
Nonsteroidal anti-inflammatory drugs NSAIDs
Prostaglandin inhibitors that are analgesic antipyretic and anti-inflammatory in action
Opioids
Centrally-acting analgesic agents related to morphine
Oral contraceptives
used for birth control administered orally
Oral hypoglycemic
used in type 2 diabetes mellitus to improve glucose metabolism and lower blood glucose levels
progestins
steroids regulating endometrial and myometrial fn used alone or in combination with estrogen for oral contraceptives
Protease inhibitors
Saquinavir, ritonavir, indinavir, and related drugs block the maturation of human immunodeficiency virus used to treat HIV infections
Salicylates
group of related chemicals that are a subclass of NSAIDs effective as analgesics, antipyretics and anti-inflammatory agents
Sedatives
given to an individual to produce relaxation and rest do not necessarily produce sleep
Selective serotonin reuptake inhibitors SSRIs
Antidepressants that act by specifically blocking the reuptake of serotonin, thus prolonging its action
Serotonin antagonists
used to block serotonin prevent emesis induced by chemotherapy, radiation therapy, and surgery
Statins (HMG-CoA reductase inhibitors)
block the synthesis of cholesterol stool dissolve existing blood clots
Sympatholytics
interfere with the storage and release of norepinephrine and epinephrine
sympathomimetics
mimic the action of dopamine, norepinephrine and epinephrine
thrombolytics
a specific group of drugs given to dissolve existing blood clots
Thyroid Hormone antagonsits
used to counteract or block the action of excessive formation of thyroid hormones
Thyroid hormones
used when thyroid hromones are not being produced or are not produced in sufficient quantities to meet the bodys physiologic needs
Tricyclic Antidepressants
inhibits the reuptake of norepinephrine and serotonin
Uricosuric Agents
act on the tubules of the kidneys to enhance the excretion of uric acid
urinary analgesics
produce a local anesthetic effect on the mucosa of the ureters and bladder to relieve burning, pain, urgency, and frequency associated with urinary tract infections
Urinary antimicrobials
substances excreted and concentrated in the urine in sufficient amounts to have and antiseptic effect on the urine and the urinary tract
Uterine relaxant
used primarily to prevent preterm labor and delivery, includes magnesium sulfateuterine
Stimulants
increase the frequency or strength of uterine contractions includes oxytocin
Vaccines
suspensions of either live, attenuated, or killed bacteria or viruses administered to induce immunity against infection of specific bacteria or viruses
Vasodilators
relax the arteriolar smooth muscle causing a dilation of the blood vessels (Calcium channel blockers, alpha -1 adrenergic blockers and hydralazine