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104 Cards in this Set
- Front
- Back
ACE inhibitors
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prevent the synthesis of angiotensin II
potent vasoconstrictor used to treat hypertension, HF, kidney disease |
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Acetylcholinesterase inhibitors
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promote the accumulation of acetylcholine, resulting in prolonged cholinergic effects
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Adrenergic
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produce effects similar to neurotransmitter norepinephrine
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Adrenergic blocking agents
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inhibit the adrenergic system preventing stimulation of the adrenergic receptors
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Aldosterone receptor antagonists
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block stimulation of mineralocorticoid receptors by aldosterone, thus reducing high blood pressure by preventing sodium reabsorption
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Aminoglycosides
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Gentamicin, tobramycin, and related antibiotics particular effective against gram-negative microorganisms noted for potentially dangerous nephrotoxicity and ototoxicity
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Amylinomimetic agent
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used to reduce elevated postprandial hyperglycemia in pt with type 1 or 2 diabetes mellitus
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Analgesics
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Narcotic and nonnarcotic relieve pain without producing loss of consciousness or reflex activity
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Androgens
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These steroid hormones produce masculinizing effect
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Anesthetics
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for example, local anesthesia, general anesthesia, cause loss of sensation with or without a loss of consciousness
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Angiotensin II receptor antagonists
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Also known as ARBs act by binding to angiotensin II receptors sites preventing angiotensin II from binding to receptor site in vascular smooth muscle , brain, heart, kidneys, and adrenal gland, thus blocking the blood pressure elevating and sodium-retaining effects of Angiotensin II
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Antacids
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reduce the acidity of the gastric contents
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antianginals
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used to prevent or treat attacks of angina pectoris most common is nitroglycerin
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antianxiety
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used to treat anxiety symptoms or disorders also known as minor tranquilizers or anxiolytics although the term tranquilizer is avoided today to prevent the misperception that the pt is being tranquilized
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Antibiotics
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used to treat infections caused by pathogenic microbes the term is often used interchangeably with antimicrobial agents
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Anticholinergics
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block the action of acetylcholine in the parasympathetic nervous system also known as cholinergic blocking agents, antispasmodics, and parasympatholytic agents
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Anticoagulants
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prevent the formation enlargement or extension of blood clots. do not dissolve existing bloodclots
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Anticonvulsants
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suppress abnormal neuronal activity in the CNS preventing seizures
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Antidepressants
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Relieve depression
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Antidiabetics
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includes insulin and amylinomimetic agent used to treat type 1 diabetes mellitus. The secretogogues and those following are used to treat type 2 DM. Secretogogues, biguanide, thiazolidinediones, alpha-glucosidas inhibitors, amylinomimetic agent, and incretin-based therapy, used in the treatment of type 2 diabetes mellitus
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Antidiarrheals
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relieve or control the symptoms of acute or chronic diarrhea
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Antidysrhythmics
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used to correct cardiac dysrhythmias ( any heart rate or rhythm other than normal sinus rhythm
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Antiemetics
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used to prevent or treat nausea and vomiting
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Antifungals
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Used to treat fungal infections
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Antiglaucoma
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Used to reduce intraocular pressure
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Antigout
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used to treat active gout attacks or to prevent future attacks
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Antihistamines
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used to treat allergy symptoms may also be used to treat motion sickness, insomnia, and other nonallergic reactions
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Antihypertensives
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used to treat elevated blood pressure (hypertension)
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Antilipemics
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used to reduce serum cholesterol and or triglycerides most common are statins
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Antimicrobials
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Chemical that eliminate living microorganisms pathogenic to the pt also called antibiotics or antiinfectives
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Antineioplastics
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also called chemotherapy agents, used alone or in combination with other treatment modalities such as radiation surgery or biologic response modifiers to treat cancer
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Antiparkinsons
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used in treatment of Parkinsons syndrome and other dyskinesias
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Antiplateltes
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Prevent platelet clumping (aggregation) thereby preventing an essential step in formation of a blood clot, most common are aspirin, clopidogrel and prasugrel
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Antipsychotics
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used to treat severe mental illnesses also know as major tranquilizer or neuroleptics, although the term tranquilizer is avoided today to prevent the misperception that the patient is being tranquilized
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Antipyretics
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used to reduce fevers associated with a variety of conditions, most common are aspirin acetaminophen, and ibuprofen
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Antispasmodics
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actually anticholinergic agents
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Antithyroid
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used to treat the symptoms of hyperthyroidism, also known as thyroid hormone antagonists propylthiouracil, methimazole
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antituberculins
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used to prevent or treat an infection caused by Mycobacterium tuberculosis
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Antitussive
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used to suppress a cough by acting on the cough center of the brain
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Antiulcer agents
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these drugs such as histamine antagonsits decrease the volume and increase the PH of gastic secretions
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Antivirals
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used to treat infections caused by pathogenic viruses
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betablockers
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inhibit the activity of sympathetic transmitters norepinephrine and epinephring used to treat angina, dysrhythmias, hypertension, and glaucoma
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bronchodiolators
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stimulate receptors within the tracheobronchial tree to relax and dilate the airway passages allowing a greater volume of air to be exchanged and improving oxygenation
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calcium channel blockers
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also called calcium ion antagonsits slow channel blockers or calcium ion influx inhibitors inhibit the movement of calcium ions across the cell membrane used to decrease dysrhythmias slow rate of contractions of the heart and cause vasodilation
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carbapenems
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antibiotcs with a broad spectrum of activity against gram-positive and gram-negative bacteria, they act by inhibiting cell wall synthesis
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Carbonic anhydrase inhibitors
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interfere with the production of aqueous humor thereby reducing intraocular pressure associated with glaucom
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Cell-stimulating agent
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improve immune fn by stimulating the activity of various immune cells cholinergic: also known as parasympathomimetics produce effects similar to those of acetylcholine
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Cholinesterase inhibitors
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cholinesterase enzymes destroy acetylcholine stopping its action. Cholinesterase inhibitors block destruction of acetylcholine, thus prolonging its action examples of cholinesterase inhibitors are demecarium and echothiophate
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coating agent
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this drug sucralfate forms a complex that adheres to the crater of an ulcer protecting it from aggravation from gastric secretions
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Colony-stimulating factors
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stimulate progenitor cells in bone marrow to increase numbers of leukocytes thereby improving immune fn
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corticosteroids
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these hormones are secreted by the adrenal cortex of the adrenal gland
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cycloplegics
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anticholinergic agents that paralyze accommodation of the iris of the eye
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cytotoxics
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agents that cause direct cell death often used for cancer therapy
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decongestants
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reduce swelling in the nasal passages caused by a common cold or allergic rhinitis usually by vasoconstriction
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Digestants
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combination products containing digestive enzymes used to treat various digestive disorders and to supplement deficiencies of natural digestive enzymes
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Digitalis glycosides
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a class of drugs also known as cardiac glycosides that increase the force of contraction and slow the heart rate, thereby improving cardiac output, digoxin is the prototype
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Diuretics
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act to increase the flow of urine
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Emetics
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used to induce vomiting
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Estrogens
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steroids that cause feminizing effects
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Expectorants
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liquefying mucus by stimulating the natural lubricant fludis the bronchial glands allowing the liquefied mucus to be expectorated or coughed up out of the bronchi and trachea
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Fluoroquinolones
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Ciprofloxacin and related agents widely used broad-spectrum antibiotics
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Gastric Stimulants
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used to increase stomach contractions relax the pyloric valve and increase peristalsis in the gastrointestinal tract result in a decrease in gastric transit time and more rapid emptying of the intestinal tract prototype is metoclopramide
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Glucocorticoids
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also known as adrenocorticosteroids are used to regulate carbohydrate fat and protein metabolism
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Gonadal hormones
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hormones produced by the testes in the male and ovaries in the female
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Herbals
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plant products usually sold as food supplements may have pharmacologic effects that are not evaluated or regulated by the FDA
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Histamine antagonists
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decrease the volume and increase the pH of gastric secretions both during the day and the night
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HMG-CoA reductase enzyme inhibitors
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also known as the statins antilipemic agents that inhibit hydroxymethyl-glutaryl coenzyme A reductase enzyme the enzyme that stimulates the conversion of HMG-CoA to mevalonic acid, a precursor in the biosynthesis of cholesterol thus reducing the potential for atherosclerosis
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Hyperuricemics
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used to decrease the production or increase the excreation of uric acid excretion of uric acid thus lowering serum uric acid levels to prevent gout
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hypnotics
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used to produce sleep
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incretin-mimetics
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used to reduce basal glucose concentrations and elevated postprandial glucose concentrations used to treat diabetes mellitus
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insulins
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Hormone required for glucose transport into the cells for energy
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Lactation suppressants
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used to prevent physiologic lactation
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laxatives
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act by variety of mechanisms to treat constipation low molecular wt heparins, derivative of heparin anticoagulants for prophylactic treatment of venous thromboembolisms macrolides: Erythromycin, azithromycin, and related antibiotics
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MAO inhibitors
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agents that block monoamine oxidase, there by preventing the degradation and prolonging the action of norepinephrine and serotonin
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Mineralocorticoids
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steroids that cause the kidneys to retain sodium and water such as fludrocortisone, miotics: cause constriction of the iris
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Mucolytics
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reduced the thickness and stickiness of pulmonary secretions by acting directly on the mucous plugs to dissolve them
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Muscle relaxants
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relieve muscle spasms
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mydriatics
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cause dilation of the iris
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Neurokinin-1 receptor antagonist
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aprepitant is the first NK1 antagonist available blocks the effects of substance P on NK1 receptors. Used to prevent acute and delayed chemotherapy-related nausea and vomiting caused by highly emetogenic antineoplastic agents
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Neuromuscular blockers
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skeletal muscle relaxants used to produce muscle relaxation during anesthesia, reduce the use and side effects of general anesthetics, used to ease endotracheal intubation and prevent laryngospasm nitrates. Metabolize to nitric oxide a potent vasodilator used to treat angina
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Nonsteroidal anti-inflammatory drugs NSAIDs
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Prostaglandin inhibitors that are analgesic antipyretic and anti-inflammatory in action
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Opioids
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Centrally-acting analgesic agents related to morphine
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Oral contraceptives
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used for birth control administered orally
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Oral hypoglycemic
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used in type 2 diabetes mellitus to improve glucose metabolism and lower blood glucose levels
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progestins
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steroids regulating endometrial and myometrial fn used alone or in combination with estrogen for oral contraceptives
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Protease inhibitors
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Saquinavir, ritonavir, indinavir, and related drugs block the maturation of human immunodeficiency virus used to treat HIV infections
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Salicylates
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group of related chemicals that are a subclass of NSAIDs effective as analgesics, antipyretics and anti-inflammatory agents
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Sedatives
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given to an individual to produce relaxation and rest do not necessarily produce sleep
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Selective serotonin reuptake inhibitors SSRIs
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Antidepressants that act by specifically blocking the reuptake of serotonin, thus prolonging its action
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Serotonin antagonists
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used to block serotonin prevent emesis induced by chemotherapy, radiation therapy, and surgery
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Statins (HMG-CoA reductase inhibitors)
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block the synthesis of cholesterol stool dissolve existing blood clots
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Sympatholytics
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interfere with the storage and release of norepinephrine and epinephrine
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sympathomimetics
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mimic the action of dopamine, norepinephrine and epinephrine
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thrombolytics
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a specific group of drugs given to dissolve existing blood clots
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Thyroid Hormone antagonsits
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used to counteract or block the action of excessive formation of thyroid hormones
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Thyroid hormones
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used when thyroid hromones are not being produced or are not produced in sufficient quantities to meet the bodys physiologic needs
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Tricyclic Antidepressants
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inhibits the reuptake of norepinephrine and serotonin
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Uricosuric Agents
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act on the tubules of the kidneys to enhance the excretion of uric acid
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urinary analgesics
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produce a local anesthetic effect on the mucosa of the ureters and bladder to relieve burning, pain, urgency, and frequency associated with urinary tract infections
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Urinary antimicrobials
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substances excreted and concentrated in the urine in sufficient amounts to have and antiseptic effect on the urine and the urinary tract
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Uterine relaxant
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used primarily to prevent preterm labor and delivery, includes magnesium sulfateuterine
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Stimulants
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increase the frequency or strength of uterine contractions includes oxytocin
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Vaccines
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suspensions of either live, attenuated, or killed bacteria or viruses administered to induce immunity against infection of specific bacteria or viruses
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Vasodilators
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relax the arteriolar smooth muscle causing a dilation of the blood vessels (Calcium channel blockers, alpha -1 adrenergic blockers and hydralazine
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