Drug Cards- Test 2- Blood & Lymph

Front 1

Primaquine

Back 1

anti-malarial (tissue schizonticide)
works against hypnozoites (liver)
P.vivax, P.ovale
can cause acute hemolytic anemia
(G6PD)

Front 2

Chloroquine

Back 2

anti-malarial (blood schizonticide)
effective, inexpensive, but....
high resistance
prevents polymerization to hemezoin
pruritis, AHA

Front 3

Mefloquine

Back 3

anti-malarial (blood schizonticide)
treatment AND prophylaxis

MENTAL effects (M=M)
CV effects

Front 4

Quinine

Back 4

anti-malarial (blood schizonticide)
ORAL- uncomplicated Pfalciparum
more toxic effects- "cinchonism"
neuromuscular, CV, oxytocic,
hypoglycemia, Blackwater fever

Front 5

Quinidine

Back 5

anti-malarial (blood schizonticide)
IV - severe, complicated Pfalciparum
more toxic effects-"cinchonism"
neuromuscular, CV, oxytocic,
hypoglycemia, Blackwater fever

Front 6

Pyrimethamine /
Sulfadoxine

Back 6

anti-malarial (blood schizonticide)
slow-acting
Tx and presumptive self-treatment
FOLATE chain inhibitors, 1- blocks DHFR, 2- blocks DHPS
AHA, sulfa allergies

Front 7

Atovaquone /
ProGuanil

(Malarone)

Back 7

anti-malarial (tissue & blood schizonticide) slow-acting
Tx and presumptive self-treatment
1- blocks mitochondrial electron transport, 2- blocks DHFR
AHA, sulfa allergies

Front 8

Doxycycline

(in children- clindamycin)

Back 8

anti-malarial
Tx and prophylaxis
adlunctive with quinine

NO children, pregnant

Front 9

warfarin

Back 9

anti-coagulant
blocks vitamin K metabolism of 2,7,9,10,C,S
ORAL, monitor via PT
NARROW THERAPUTIC INDEX, needs frequent monitoring
TERATOGENIC

Front 10

heparin
(UFH) (un-fractionated heparin)

Back 10

anti-coagulant
interacts with AT3 to inhibit 2a, 10a
IV- unpredictable response
hospital dosing, monitor via aPTT
1-4% risk of HITT

Front 11

enoxaparin

Back 11

anti-coagulant
LMWH- low molecular weight heparin
interacts with AT3 to inhibit 10a only
SubQ- predictable effect, less need to monitor
home dosing, more expensive, but not clinically delivered
1 - 4% risk of HITT

Front 12

dalteparin

Back 12

anti-coagulant
LMWH- low molecular weight heparin
interacts with AT3 to inhibit 10a only
SubQ- predictable effect, less need to monitor
home dosing, more expensive, but not clinically delivered
1 - 4% risk of HITT

Front 13

ardeparin

Back 13

anti-coagulant
LMWH- low molecular weight heparin
interacts with AT3 to inhibit 10a only
SubQ- predictable effect, less need to monitor
home dosing, more expensive, but not clinically delivered
1 - 4% risk of HITT

Front 14

tinzeparin

Back 14

anti-coagulant
LMWH- low molecular weight heparin
interacts with AT3 to inhibit 10a only
SubQ- predictable effect, less need to monitor
home dosing, more expensive, but not clinically delivered
1 - 4% risk of HITT

Front 15

fondaparinux

Back 15

anti-coagulant
5-sugar selective factor Xa inhibitor
SubQ, longer half-life, no monitoring
DVT, PE, UA, STEMI, NSTEMI

Front 16

hirudin

Back 16

anticoagulant
Direct Thrombin inhibitor
leech saliva
dissolves soluble/fibrin-bound thrombin

Front 17

lepirudin

Back 17

anticoagulant
Direct Thrombin inhibitor
Recombinant derivative of hirudin, but allergy risk
dissolves soluble/fibrin-bound thrombin
alternative in HITT cases

Front 18

bivalirudin

Back 18

anticoagulant
Direct Thrombin inhibitor
Bivalent analog of hirudin
dissolves soluble/fibrin-bound thrombin
for PCI during HITT

Front 19

argotraban

Back 19

anticoagulant
Direct Thrombin inhibitor
Bivalent analog of hirudin
dissolves soluble/fibrin-bound thrombin
alternative in HITT cases

Front 20

ASA- acetylsalicylic acid
(low dose)

Back 20

anti-platelet
IRreversibly blocks COX-1 (in low dose), synthesis of TxA2 (thromoxane A2)
vaso-dilator, anti-aggregator
for thrombus, PCI, UA, STEMI, NSTEMI

Front 21

clopidogrel

Back 21

anti-platelet
ADP receptor blocker (irreversible)
prevents platelet aggregation
ORAL
for thrombus, PCI, UA, STEMI, NSTEMI

Front 22

prasugrel

Back 22

anti-platelet
ADP receptor blocker (irreversible)
prevents platelet aggregation
ORAL
for thrombus, PCI, UA, STEMI, NSTEMI

Front 23

ticlopidine

Back 23

anti-platelet
ADP receptor blocker (irreversible)
prevents platelet aggregation
ORAL
for thrombus, PCI, UA, STEMI, NSTEMI

Front 24

abciximab

Back 24

anti-platelet
glycoprotein IIb/IIIa receptor blocker
prevents platelet aggregation
“tight’ binding to GP IIb/IIIa receptor, 36 hrs

Front 25

eftifibitide

Back 25

anti-platelet
glycoprotein IIb/IIIa receptor blocker
prevents platelet aggregation
“loose" binding to GP IIb/IIIa receptor, 4 hrs

Front 26

tibrofan

Back 26

anti-platelet
glycoprotein IIb/IIIa receptor blocker
prevents platelet aggregation
“loose" binding to GP IIb/IIIa receptor, 4 hrs

Front 27

streptokinase

Back 27

THROMBOLYTIC
derived from B-strep
Catalyze plasminogen to plasmin, degrades fibrin
risk of allergic rxn
STEMI, DVT, PE, stroke

Front 28

urokinase

Back 28

THROMBOLYTIC
derived from kidney
Catalyze plasminogen to plasmin, degrades fibrin
STEMI, DVT, PE, stroke

Front 29

anistreplase

Back 29

THROMBOLYTIC
complex of bacterial & plasminogen
Catalyze plasminogen to plasmin, degrades fibrin
STEMI, DVT, PE, stroke

Front 30

reteplase

Back 30

THROMBOLYTIC
recombinant tPA
Catalyze plasminogen to plasmin, degrades fibrin
STEMI, DVT, PE, stroke

Front 31

alteplase

Back 31

THROMBOLYTIC
recombinant tPA
Catalyze plasminogen to plasmin, degrades fibrin
STEMI, DVT, PE, stroke

Front 32

tenecteplase

Back 32

THROMBOLYTIC
recombinant tPA
Catalyze plasminogen to plasmin, degrades fibrin
STEMI, DVT, PE, stroke

Front 33

ferrous fumerate

Back 33

iron supplement, ORAL
25% absorption
causes GI irritation, toxic, corrosive
acute iron toxicity

Front 34

ferrous sulfate

Back 34

iron supplement, ORAL
25% absorption
causes GI irritation, toxic, corrosive
acute iron toxicity

Front 35

ferrous gluconate

Back 35

iron supplement, ORAL
25% absorption
causes GI irritation, toxic, corrosive
acute iron toxicity

Front 36

iron dextran

Back 36

iron supplement, parental (one dose)
for malabsorption, intolerance
causes skin discoloration, pain
poss hypersensitivity rxns (I or IV)

Front 37

iron sucrose

Back 37

iron supplement, parental (one dose)
for malabsorption, intolerance
causes skin discoloration, pain
poss hypersensitivity rxns (I or IV)

Front 38

sodium ferric gluconate complex in sucrose

Back 38

iron supplement, parental (one dose)
for malabsorption, intolerance
causes skin discoloration, pain
poss hypersensitivity rxns (I or IV)

Front 39

vitamin B12

Back 39

deficiency causes macrocytic anemia & demyelination
can take years to manifest
diet, drugs, GI disease, lack of intrinsic factor
given subQ

Front 40

folic acid

Back 40

deficiency causes macrocytic anemia
a few weeks to manifest
diet, drugs, malabsorption, pregnancy
given ORALLY

Front 41

epoetin alfa

Back 41

Hematopoietic Growth Factor
stimulates RBC production

Front 42

darbepoetin alfa

Back 42

Hematopoietic Growth Factor
longer half-life
stimulates RBC production

Front 43

sargramostim

Back 43

GM-CSF
stimulates netrophil, macrophage production

Front 44

filgastim

Back 44

G-CSF
stimulates neutrophil, production

Front 45

peg-filgastim

Back 45

G-CSF
stimulates neutrophil, production
longer half-life

Front 46

oprelvekin

Back 46

IL-11
stimulates platelet production

Front 47

Nystatin

Back 47

anti-fungal, topical or oral use only
acts on fungal cell membrane, binds to ergosterol

Front 48

Amphotericin B

Back 48

anti-fungal, IV
acts on fungal cell membrane, binds to ergosterol
DOC for many severe, invasive fungal infections
severe renal toxocity, "cytokine storm"

Front 49

Flucytosine

Back 49

anti-fungal, ORAL
pro-drug of 5-fluorouracil, an anti-metabolite
always used in combination with Amphotericin B
NVD, BMD (bone marrow depression)

Front 50

Griseofulvin

Back 50

anti-fungal
anti-mitotic, ORAL
Tinea infections, but 2nd-line drug
Hepato-toxicity, p450 INducer

Front 51

Terbinafine

Back 51

anti-fungal
DOC for skin, nail infections
inhibits squalene metabolism
liver tox, neutropenia, CYP2D6 blocker
faster, more effective than azoles

Front 52

Ketoconazole

Back 52

anti-fungal, ORAL, topical
blocks ergosterol metabolism, and human p450
Tineas, steroid dysfunctions
older drug with more problems
May see hormonal deficiency side effects
oral absorption very acid-dependent

Front 53

Fluconazole

Back 53

anti-fungal, ORAL, IV
blocks ergosterol metabolism
DOC for several systemic and CNS fungal infections
kidney elimination

Front 54

Itraconazole

Back 54

anti-fungal, ORAL, IV
blocks ergosterol metabolism
first-line for systemic fungal infections

Front 55

Voriconazole

Back 55

anti-fungal, ORAL, IV
blocks ergosterol metabolism
systemic fungal infections
esp. ASPERGILLOSIS
visual disturbances

Front 56

Caspofungin

Back 56

anti-fungal, IV
impairs cell wall, by glucan monomers
Salvage therapy for Candida, Aspergillus

Front 57

Clotrimazole

Back 57

anti-fungal, topical, oral, OTC
Tinea, thrush, vaginal yeast infections

Front 58

Micanazole

Back 58

anti-fungal, topical, oral, OTC
Tinea, thrush, vaginal yeast infections

Front 59

Amifostine

Back 59

rescue drug- cancer chemo
during chemotherapy, for cis-Platin, alkylating agents
reduces nephrotoxicity

Front 60

Mesna

Back 60

rescue drug- cancer chemo
during chemotherapy, for alkylating agents
reacts with acrolein
reduces bladder toxicity

Front 61

N-acetyl cysteine
(MucoMyst)

Back 61

rescue drug- cancer chemo
during chemotherapy, for alkylating agents
reacts with acrolein
reduces bladder toxicity

Front 62

Cyclophosphamide

Back 62

anti-cancer, alkylating agent, nitrogen mustard
DNA cross-linking
most types of cancer - commonly used
pro-drug, needs liver metabolism
BMD, bloody bladder (use mesna, NAC)

Front 63

Carmustine

Back 63

anti-cancer, alkylating agent, nitroso-urea
DNA cross-linking, alkylator
brain cancer (crosses BBB)
profound BMD, 4 other tox= kidney, liver, CNS, lung

Front 64

Lomustine

Back 64

anti-cancer, alkylating agent, nitroso-urea
DNA cross-linking, alkylator
brain cancer (crosses BBB)
profound BMD, 4 other tox= kidney, liver, CNS, lung

Front 65

cis-Platin

Back 65

anti-cancer, alkylating agent, platinum complex
DNA cross-linking
tesicles, ovary, bladder, head/neck
severe NVD, anaphylaxis
Neuro, renal tox (use amifostine)

Front 66

Leucovorin

Back 66

Rescue drug- cancer chemo

used with methotrexate to reduce damage to bone marrow, GI tract

Front 67

Allopurinol

(used during chemotherapy)

Back 67

rescue drug during chemo
inhibits xanthine oxidase in purine metabolism
prevents urate overload when treating blood cancers
NOTE: need to reduce dose of 6-MP, 6-TP when using allopurinol

Front 68

Methotrexate

Back 68

anti-cancer, anti-folate, anti-purine
inhibits DHFR, blocks DNA synthesis
Leukemias, lymphomas, breast ca
also- for psoriasis, rheumatoid arthritis
resistance by change in DHFR, decreased uptake
BMD, ulcers in GI, ulcers in oral

Front 69

5-fluorouracil
(5-FU)

Back 69

anti-cancer, anti-pyrimadine
blocks DNA synthesis by blocking thymine synth.
breast, colo-rectal, basal cell carcinoma
resistance by change in enzymes
BMD, GI mucositis
NOTE: leucovorin INCREASES tox

Front 70

Capecitabine

Back 70

anti-cancer, anti-pyrimadine
oral version of 5-fluorouracil
breast, colo-rectal, basal cell carcinoma
BMD, GI mucositis
NOTE: leucovorin INCREASES tox

Front 71

Gemcitabine

Back 71

anticancer, anti pyrimadine
inhibits DNA poly, chain termination
Breast, NSCLC, pancreatic, ovary
causes neutropenia

Front 72

Cytarabine

Back 72

anticancer, anti pyrimadine
inhibits DNA poly, chain termination
ALL, non-HL
causes BMD, ataxia

Front 73

6-mercaptopurine

(6-MP)

Back 73

anticancer, anti purine
needs to be activated by HGPRT
ALL, AML, CML
resisted by lowering HGPRT
causes BMD, hyperuricemia
allopurinol reduces metabolism (lower the dose)

Front 74

6-thioguanine

(6-TG)

Back 74

anticancer, anti purine
needs to be activated by HGPRT
ALL, AML, CML
resisted by lowering HGPRT
causes BMD, hyperuricemia
allopurinol reduces metabolism (lower the dose)

Front 75

Prednisone

(chemotherapy)

Back 75

anti-cancer, glucocorticoid (hormone)
suppresses lymphocyte production, induces apoptosis
for ALL, acute lymphomas
causes "Steroid Man" effects

Front 76

Tamoxifen

Back 76

anti-cancer, hormone blocker
competitively blocks estrogen receptor
good for ER+ Breast cancer
can be outcompeted by endogenous estrogen
mild side effects, can raise risk of uterine cancer

Front 77

Anastrozole

Back 77

anti-cancer, hormone synthesis blocker
blocks estrogen synthesis
good for ER+ Breast cancer
SALVAGE therapy beyond tamoxifen

Front 78

Bortezomib

Back 78

anti-cancer, signal pathway blocker
blocks NF-kappa-B, inhibits 26s proteosome (stops cell cycle)
for multiple myeloma
causes BMD

Front 79

Hydroxyurea

Back 79

anti-cancer, (anti ribonucleotide reductase)
blocks ribose to deoxyribose sugar synthesis
for melanoma, CML, ovarian cancer
causes myelosuppression (low RBCs, platelets, PMNs)

Front 80

Imatinib

Back 80

anti-cancer, (aka Gleevac)
monoclonal antibody
blocks signaling pathway of bcr-abl tyrosine kinase
for CML (philadelphia chromosome)

Front 81

Trastuzumab

Back 81

anti-cancer, (aka Herceptin)
monoclonal antibody
blocks signaling pathway at HER2 receptor (EGFR)
for aggressive ER- Breast cancers
some cardiotox

Front 82

Bevacizumab

Back 82

anti-cancer, monoclonal antibody
binds VEGF, prevents receptor activation
blocks angiogenesis, prevents tumor expansion thru increased blood supply
for metastatic colo-rectal cancer
causes GI tox - ulcers & perforations

Front 83

vinCristine

Back 83

anti-cancer / "natural"
anti-mitotic - binds to G-tubulin
for Leukemias, Non-Hodgkins lymphomas
resistance by p-glycoprotein
causes neurotoxicity- sensory, autonomic, muscular
FATAL if given intrathecally

Front 84

vinBlastine

Back 84

anti-cancer / "natural"
anti-mitotic - binds to G-tubulin
for Leukemias, all lymphomas, breast, testicles
resistance by p-glycoprotein
causes myelosuppression (remember B =B, vinBlastine, Blood, Bone)

Front 85

Paclitaxel

Back 85

anti-cancer / "natural"
anti-mitotic - hyperstabilizes tubulin
for breast, ovarian cancers
causes BMD, neuropathy (sensory)

Front 86

Docetaxel

Back 86

anti-cancer / "natural"
anti-mitotic - hyperstabilizes tubulin
for breast, prostate, NonSCLC
causes BMD, neurotox (sensory & motor), and fluid retention

Front 87

Etoposide

("e-TOPO-side")

Back 87

anti-cancer / "natural"
inhibits TOPO 2- causes DNA strand breaks
resistance by p-glycoprotein, other mechanisms
for testicular, SCLC (small cell)
causes BMD

Front 88

Irinotecan

Back 88

anti-cancer / "natural"
inhibits TOPO 1- causes DNA strand breaks
for metastatic COLON cancer
causes BMD, diarrhea (poss FATAL!)

Front 89

Topotecan

"TOPO-tecan"

Back 89

anti-cancer / "natural"
inhibits TOPO 1- causes DNA strand breaks
for ovarian, SCLC (small cell)
causes BMD

Front 90

Dactinomycin

Back 90

anti-cancer / "natural"
intercalates into DNA, stops polymerase
resistance by p-glycoprotein
for pediatric tumors (Wilms, Ewings, etc), germcell tumors
causes BMD, stomatitis, proctitis (inflammation at both ends)

Front 91

Doxorubicin

-rubicin = ruby red = blood, heart

Back 91

anti-cancer / "natural"
intercalates into DNA, stops TOPO 2
forms damaging free radicals
resistance by p-glycoprotein
broad-spectrum chemo (incl blood)
causes CARDIO-TOX, BMD, and is a tissue vesicant

Front 92

Daunorubicin

-rubicin = ruby red = blood, heart

Back 92

anti-cancer / "natural"
intercalates into DNA, stops TOPO 2
forms damaging free radicals
resistance by p-glycoprotein
blood cancers- ALL, non-lymphocytic leukemias
causes CARDIO-TOX, BMD, and is a tissue vesicant

Front 93

Bleomycin

Back 93

anti-cancer / "natural"
causes DNA strand breaks by chelating Fe, free radicals
for lymphomas, squamous cell, testicular, head/neck ca.
causes lung fibrosis, skin toxicity
LOW BMD!

Front 94

L-asparaginase

Back 94

anti-cancer / "natural"
enzyme, hydrolyzes circulating L-asparagine, blocks tumor cells of amino acid
for lymphocytic leukemias, ALL
resistance by increased asparagine synthesis
ACUTE cause = anaphylaxis
causes- clotting problems (+/-), glucose intolerance, CNS, pancreatitis

Front 95

Prednisone

Back 95

immunosuppressant- glucocorticoid
used in prevention AND treatment of transplants and autoimmune
inhibits some T-cell populations
inhibits IL-2 production (macs & PMNs)
causes "Steroid Man" effects- skin, lipids, eyes, GI tract, osteoporosis, infections

Front 96

Cyclosporine

Back 96

immunosuppressant- calcineurin inhibitor
used in prevention only in transplants and autoimmune
binds to 'cyclophilin', inhibits IL-2 gene transcription
causes renal tox, liver tox, BP increase, hyperkalemia
ZEBRAS- gingival hyperplasia, hirsuitism

Front 97

Tacrolimus

Back 97

immunosuppressant- calcineurin inhibitor
used in prevention only in transplants and autoimmune
binds to 'FKBP', inhibits IL-2 gene transcription
causes renal tox, diabetes

Front 98

Sirolimus

Back 98

immunosuppressant- anti-proliferative agent
used in prevention only in transplants and autoimmune
inhibits signal downstream of IL-2 - mTOR
causes hyperlipidemia, myelodepression, NO renal tox

Front 99

Azathioprine

Back 99

immunosuppressant- anti-proliferative
pro-drug- metabolized to 6-MP (6-mercatopurine)
blocks DNA synthesis in stimulated T-cells
used in prevention, maintenance only in transplants and autoimmune
Depresses both cell mediated and antibody mediated reactions
** INACTIVATED by xanthine oxidase- must reduce dose when using with allopurinol **
BMD, GI tox, mutagenic

Front 100

Mycophenolate mofetil

Back 100

immunosuppressant- anti-proliferative
Selective, noncompetitive inhibitor of IMPDH
blocks B & T-cell proliferation
used in prevention, maintenance only in transplants and autoimmune
Depresses both cell mediated and antibody mediated reactions
less tox than other anti-metabolites = BMD, GI tox

Front 101

ALG

(anti-lymphocyte globulin)

Back 101

immunosuppressant- anti-bodies
Used as ‘adjuvants’ to ↓ # circulating T-cells, leaves humoral fxn
ANTISERA produced by large animals
Primarily used in kidney transplants
Used to treat steroid resistant rejections
AE- mainly allergic effects- rash, local pain

Front 102

ATG

(anti-thymocyte glogulin)

Back 102

immunosuppressant- anti-bodies
Used as ‘adjuvants’ to ↓ # circulating T-cells, leaves humoral fxn
ANTISERA produced by large animals
Used during acute rejection episodes
Used to treat steroid resistant rejections
AE- mainly allergic effects- rash, local pain

Front 103

Muromonab-CD3

(OKT3)

Back 103

immunosuppressant- anti-bodies
Used as ‘adjuvants’ to ↓ # circulating T-cells, leaves humoral fxn
T-cell specific murine monoclonal Ab
Used during acute rejection episodes
Shuts down activation of T-cell proliferation and impairs cytotoxic T-cell function
AE- fairly toxic, allergic effects- "cytokine storm"

Front 104

Daclizumab

Back 104

immunosuppressant- anti-bodies
Monoclonal antibodies to part of IL-2 receptor (CD25)
Probably prevents IL-2 from binding to activated lymphocytes
for prophylaxis against acute rejection of renal transplants
causes infections & allergic type symptoms

Front 105

Acyclovir

Back 105

anti-viral, against DNA viruses
a guanosine analog
activity against: HSV-1, HSV-2, VZV
MOA = Phosphorylated by viral thymidine kinase, inhibits viral DNA synthesis
AE- oral=few, IV= acute renal failure, neuro tox

Front 106

Ganciclovir

Back 106

anti-viral, against DNA viruses
a guanosine analog
activity against: CMV
MOA = Phosphorylated by CMV phosphotransferase , inhibits viral DNA synthesis
AE- BMD, neuro tox

Front 107

Foscarnet

Back 107

anti-viral, against DNA viruses
A pyrophosphate analog
Serious HSV and CMV infections
MOA = Inhibits viral DNA polymerase
AE- renal, hypocalcemia, electrolyte problems

Front 108

Zanamivir

Back 108

anti-viral, Neuraminidase Inhibitor
inhaled
Effective against both influenza A & B
MOA = prevents the release of progeny virions
AE- bronchospasm

Front 109

Oseltamivir

Back 109

anti-viral, Neuraminidase Inhibitor
ORAL
Effective against both influenza A & B
MOA = prevents the release of progeny virions
AE- NV, rare neuropsychiatric events in children

Front 110

Amantidine

Back 110

anti-viral, Viral Uncoating Inhibitor
Treatment of Influenza A
MOA = prophylaxis, if given BEFORE exposure, Pre-emptive treatment
AE- enters CNS, causes skittishness, GI problems

Front 111

Rimantidine

Back 111

anti-viral, Viral Uncoating Inhibitor
blocks M2 proton channel
Treatment of Influenza A only
MOA = prophylaxis, if given BEFORE exposure, Pre-emptive treatment
AE- GI problems, less CNS

Front 112

Ribavarin

Back 112

anti-viral, guanosine analog
treats Respiratory Syncytial Virus (RSV), hepatitis C
MOA = Interferes with cellular GTP production
AE = anemia, pulmonary deterioration
Pregnancy category X

Front 113

Interferon-alfa

Back 113

anti-viral, transcription factor
treats Chronic hepatitis B, C viral infections
MOA = Turn on gene expression of proteins with antiviral effects
AE = many toxicities, incl. myelosuppression, Flu-like symptoms, Marked CNS effects

Front 114

Lamivudine

Back 114

anti-viral, Nucleoside analog
treats Chronic hepatitis B viral infections
MOA = Antimetabolite, causes viral DNA chain termination
AE = Lactic acidosis with hepatic steatosis (rare but potentially fatal)

Front 115

Lamivudine

Back 115

anti-viral, Nucleoside analog
NRTIs (nuke)
anti-HIV

Front 116

Zidovudine

Back 116

anti-viral, Nucleoside analog
NRTIs (nuke)
anti-HIV

Front 117

Stavudine

Back 117

anti-viral, Nucleoside analog
NRTIs (nuke)
anti-HIV

Front 118

Didanosine

Back 118

anti-viral, Nucleoside analog
NRTIs (nuke)
anti-HIV

Front 119

Zalcitabine

Back 119

anti-viral, Nucleoside analog
NRTIs (nuke)
anti-HIV

Front 120

Ritonavir (RTV)

co-drug

Back 120

anti-viral, Protease inhibitor
anti-HIV
used mainly for pharmacologic enhancement of Protease Inhibitors.
prevents immature virions from becoming mature, infectious viruses

Front 121

Indinavir

Back 121

anti-viral,
Protease inhibitor
anti-HIV
prevents immature virions from becoming mature, infectious viruses

Front 122

Amprenavir

Back 122

anti-viral,
Protease inhibitor
anti-HIV
prevents immature virions from becoming mature, infectious viruses

Front 123

Nelfinavir

Back 123

anti-viral,
Protease inhibitor
anti-HIV
prevents immature virions from becoming mature, infectious viruses

Front 124

Saquinavir

Back 124

anti-viral,
Protease inhibitor
anti-HIV
prevents immature virions from becoming mature, infectious viruses

Front 125

Efavirenz

Back 125

anti-viral, (NNRTIs or non-nuke)
Nonnucleoside reverse transcriptase inhibitor
anti-HIV
Have potent antiviral activity

Front 126

Nevirapine

Back 126

anti-viral, (NNRTIs or non-nuke)
Nonnucleoside reverse transcriptase inhibitor
anti-HIV
Have potent antiviral activity

Front 127

Enfuvirtide

Back 127

anti-viral, Fusion inhibitor
anti-HIV
Blocks the entry of HIV-1 into CD4+ cells by inhibiting the fusion of viral and cellular components

Front 128

Maraviroc

Back 128

anti-viral, Entry Inhibitor
anti-HIV
CCR5 co-receptor antagonist

Front 129

Raltegravir

Back 129

anti-viral,
Integrase inhibitor
anti-HIV