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19 Cards in this Set

  • Front
  • Back

The Route of Drugs are grouped into two classes. Mention them:

Systemic Route


•Local Route



Systemic route: These are drugs administered and intended to enter blood circulation and distribute to the body and target site.



Local Route: These are drugs administered to act locally on the applied area. Hence drug concentration is high at the site of application and avoid from spreading to other sites.

Systemic route is subclassified into two, mention them:

ENTERAL - Oral, Rectal & Sublingual


•PARENTERAL

Mention the 3 Advantages and 3 Disadvantages of ORAL Route of administering Drugs and give the types of drugs:

ADVANTAGES


• It can be self administered


•It is the cheapest form of administration


•Safest route of Administration


•convinient for patient.



DISADVANTAGES


Gastric irritation could lead to vomiting.


Slow onset of action.


• Absorption may be variables.


•Not useful in unconscious patient.


•Drug might be destroyed by digestive juice.




Examples:


- Tablet


- Capsule


- Solutions


- Syrups


- Elixirs

Mention the 3 Advantages and 3 Disadvantages of RECTAL Route of administering Drugs and give the types of drugs:

Advantages


• useful in unconscious patient.


• Direct absorption throught the external and internal haemorrhiodal vein.


• Systemic effect



Dasadvantages


•Inconvinient


•irritation and may cause inflammation


•Slow and irregular absorption.



Examples:


- ointments


- Suppositories


- Tablet


- Solutions

Mention the 3 Advantages and 3 Disadvantages of Sublingual Route of administering Drugs and give the types of drugs:

Advantages


Rapid onset of Action.


No first pass metabolism.


• Systemic effect



Disadvantages


•Inconvinient


chances of spitting the drugs



Examples:


- Tablet


- Troches/ lozenges

The systemic route of drugs is grouped into two: mention them:

Enteral: Drugs administered through the alimentary canal. Examples: oral, Rectal, Sublingual


Parenteral: Drug administered other than alimentary canal. Examples: Inhalation, injection, Transcutaneous and Transmucusal.

Mention the 3 Advantages and 3 Disadvantages of Parenteral Route of administering Drugs and give the types of drugs:

Advantages


Can be administered to unconscious patient.


Rapid onset of Action.


No first pass metabolism.


• Avoids modification by alimentary juice or liver enzymes.


• Drug-dose accuracy.



Disadvantages


More expensive


Self medication is difficult


likely to cause infection if equipment are not well sterilized.


•Important structures might be damaged. E.g Nerves and arteries.



Examples:- Injections- inhalers

There are three primary route of Injections mention them:

Subcutaneous (subQ)


•Intravenous (IV)


•Intramuscular (IM)

Mention the 2 Advantages and 2 Disadvantages of SUBCUTANEOUS injection Route of administering Drugs and give the types of drugs:

Advantages


self injection is possible


High Bioavailability


Action is sustained and uniform



Disadvantages


only small volume can be injected (1-2ml)


Not suitable for shock patient


Drug Absorption is slower than IM route.



Examples:- Solutions

Mention the 3 Advantages and 3 Disadvantages of INTRAMUSCULAR Route of administering Drugs and give the types of drugs:

Advantages


Depot preparation can be used.


High bioavailability and Avoids first pass metabolism.


Fast absorption and rapid onset of action



Disadvantages


self medication is difficult


causes pain while injecting.


Volume of injection should not pass 10mlExamples:- solutions

Mention the 3 Advantages and 3 Disadvantages of INTRAVENOUS Route of administering Drugs and give the types of drugs:

Advantages


immediate actions and Response


Can be given to unconscious patient.


Almost 100% Bioavailability


Disadvantages


Not self administered


local irritation might cause PHEBITIS


low chances of reversal



Examples:-

What type or mode of injection is used in Tuberculin or Allergy testing?

Intra-dermal Injection

Anti malignancy compound are administered through what mode of injection?

Intrathecal and intra-arterial

Administration of drug into the subarachnoid space of spinal cord is under what mode of injection

Intrathecal

Administration of drugs directly into the serum membrane is what mode of injection?

Intraperitoneal

Mention the 3 Advantages and 3 Disadvantages of INHALATION Route of administering Drugs and give the types of drugs:

Advantages


Self administration


Rapid onset of action


Avoids first pass metabolism



Disadvantages


Dose may cause irritation to the mucosal respiratory tract


Difficulty in dose estimation


Expensive dosage form Examples:- Earosols

Study the rest

DONE🥂

Write short note on Local Application of Drugs route

Define Enema and the types