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2 Cards in this Set
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- Back
- 3rd side (hint)
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Fenoldopam (MOA & PK)
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MOA - Similar effects to dopamine on dopamine receptors; stimulates a2 receptors, presynaptic sympathetic inhibition
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PK - IV; very short half-life (minutes); degraded rapidly by COMT and MAO; Catechol moiety prevents ready absorption and CNS penetration; D1>>D2
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Fenoldopam (CU & T)
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CU - Severe hypertension
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T - Arrhythmias, hypertension, cerebral hemorrhage, tachycardia, anxiety, reflex bradycardia increased risk of cardiac ischemia
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