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28 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Name direct cholinergic agents
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Carbechol
Pilocarpine Bethanocol |
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Name the indirect cholinergic agonists (anti-acetylcholinesterases)
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Neostigmine
Donepezil |
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Name the cholinergic antagonists
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Atropine
Ipratropium Glycopyrrolate Scopalamine |
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Nicotinic antagonist
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Hexamethonium
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Cholinesterase regenerator
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Pralidoxime
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α1, α2, β1, β2 agonist
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Epinephrine
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α1, α2, β1 agonist
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Norepinephrine
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D1 = D2 > β1 > α1 agonist
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Dopamine
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β1 = β2 agonist
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Isoproterenol
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β1 > β2 agonist
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Terbutaline
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α1 > α2 agonist
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Phenylephrine
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α-blockers (antagonists)
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Prazosin
Terazosin Phenoxybenzamine |
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β-blockers
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Nonselective: Labetalol, Timolol, Propranolol
β1 Selective: Metoprolol, Esmolol, Atenolol |
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What are the 4 important pharmacokinetic equations?
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Vd x Co = D x F
t1/2 = (.7)Vd/ CL LD = Css x Vd MD = Css x CL |
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What agents stimulate the release of NE from the presynaptic bouton?
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Amphetamine
Ephedrine Tyramine |
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What agents potentiate the action of NE by inhibiting its reuptake into the presynaptic cell?
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Cocaine
Amphetamine TCA |
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What are the 5 classes of drugs used to treat glaucoma?
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β-blockers
α-agonists Prostaglandins Muscarinics CA inhibitors (diuretics) |
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HY: gout, mental retardation, lip-biting
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Lesch Neyhan
* Deficiency of? |
HGPRT enzyme in the purine salvage pathway
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HY: hypertension, hypokalemia, metabolic alkalosis
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Primary Hyperaldosteronism (Conn's)
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HY: fever, night sweats, weight loss
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TB or lymphoma
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HY: adrenal hemorrhage due to meningococcemia
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Waterhouse-Friderichsen
* Other associations? |
DIC, hypotension
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HY: blue sclera
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Osteogenesis Imperfecta
* Defect? |
Type I collagen defect
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HY: C's of Huntington Disease
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Chorea
Crazy (dementia) CAG (trinucleotide repeats) Caudate degeneration ↓ Ach |
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What nerve is damaged when a patient presents with scapular winging?
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Long thoracic
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What nerve is damaged when a patient presents with loss of forearm pronation?
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Median
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What nerve is damaged when a patient cannot abduct or adduct the fingers?
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Ulnar (especially distal)
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What nerve is damaged when a patient has weak lateral rotation of the arm?
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Suprascapular
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What nerve is damaged when a patient is unable to abduct the arm above 10 degrees?
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Suprascapular
* What muscle is responsible for the first 10 degrees? |
Supraspinatus
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