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15 Cards in this Set
- Front
- Back
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carried in nasopharynx human to human spread diphtheria toxin and gray psuedomembrane from dead cells |
corynebacterium diphtheria |
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gram + rods palisades |
histology of diphtheria |
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ADP ribosylation of elongation factor 2 preventing protein synthesis, only possible with B-phage |
mechanism of diphtheria toxicity |
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Toxoid (formalin treated toxin) vaccine |
diphtheria vaccine |
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gram - rod with flagella opportunistic pathogen with no human to human transmission |
Pseudomonas Aeruginosa |
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chronic colonization of lungs of CF kids, causing pneumonia, and frequently fatal bacteremias and sepsis |
clinical symptoms of P. Aeruginosa |
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alginate capsule, ADP ribosylating Elongation factor 2 exotoxin, multiple abx resistances, quorum sensing, biofilm formation |
Psuedomonas Aeruginosa Virulence factors |
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fruity odor, blue green polycyanin pigment, multiple abx resistances |
Psuedomonas Aeruginosa diagnosis signs |
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colonized ciliated epithelium in trachea and bronchi, mild catarrhal leading to paroxysms of coughing, gram - |
bordetella pertusis |
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ADP ribosylation of Gi protein which usually deactivates adenylate cyclase- causing ion imbalance via continual production of cAMP; 5 binding subunits, 1 active |
pertussis toxin |
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mild pneumonia, 10% of CA, cough and low grade fever |
Chlamydophila Pneumoniae, walking pneumonia |
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gram negative, no peptidoglycan elementary body= infectious form reticulate body= intracellular replicative form |
chlamydial microbiology |
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adhesive organelle, no peptidoglycan or cell wall, sterols from host origin, community acquired, usually lower lobe |
Mycoplasma Pneumoniae |
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fried egg cultured appearance and cold agglutinins from IgM antibodies breaking down RBCs |
lab dx of mycoplasma Pneumoniae |
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unique feature of chlamydia |
obligate intracellular pathogens that grow in vacuoles |
