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9 Cards in this Set
- Front
- Back
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toxicity paclitaxel
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myelosuppression, hypersensitivity
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toxicity trastuzumab
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cardiotoxicity
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use of vincristine, vinblastine
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lymphoma (MOPP), Wilm's tumor, choriocarcinoma
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paclitaxel
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anti-cancer agent binds to tubulin so spindle cannot break down
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tamoxifen mech
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estrogen R mixed agonist/antagonist (SERM), effectively blocks binding of estrogen
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toxicity tacrolimus
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nephrotox, peripheral neuro, HTN, pl eff, hyperglycemia
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azathioprine
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deriv 6MP interferes with syn and metab nucleic acids. toxic to prolifer lymphocytes
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use azathioprine
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kidney transplant, autoimmune (GN, AHA)
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toxicity of cyclosporine
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nephrotoxic-preventable with mannitol diuresis
predisposes pts to viral infxn and lymphoma |
