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9 Cards in this Set

  • Front
  • Back
toxicity paclitaxel
myelosuppression, hypersensitivity
toxicity trastuzumab
cardiotoxicity
use of vincristine, vinblastine
lymphoma (MOPP), Wilm's tumor, choriocarcinoma
paclitaxel
anti-cancer agent binds to tubulin so spindle cannot break down
tamoxifen mech
estrogen R mixed agonist/antagonist (SERM), effectively blocks binding of estrogen
toxicity tacrolimus
nephrotox, peripheral neuro, HTN, pl eff, hyperglycemia
azathioprine
deriv 6MP interferes with syn and metab nucleic acids. toxic to prolifer lymphocytes
use azathioprine
kidney transplant, autoimmune (GN, AHA)
toxicity of cyclosporine
nephrotoxic-preventable with mannitol diuresis
predisposes pts to viral infxn and lymphoma