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55 Cards in this Set
- Front
- Back
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Normal Fasting Glucose
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70-110
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A1C good control level
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<6.5
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BP goal in Diabetes
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<130/80
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Lipid goals in diabetes
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LDL: <100, <70 in high risk
Triglycerides: <150 HDL: >40 |
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Humalog
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Lispro: rapid acting
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Novolog
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Aspart: Rapid acting
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Humulin/Novolin R
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Regular insulin: Short acting
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Humulin/Novolin N
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NPH: Intermediate acting
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Lantus
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Glargine: Long acting
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Hypoglycemia characteristics
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Sudden fatigue, tachycardia, sweating, confusion, headache
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Ketoacidosis characteristics
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Positive glycosuria and ketonuria, thirst, "Juicy Fruit" breath, rapid pulse, drowsiness, loss of appetite
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Insulin Secretagugues (sulfonylureas and Meglitinides) Indications
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Type 2 diabetes: Not in children, pregnant and lactating women or type 1
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Insulin Secretagogues (sulfonylureas and Meglitinides) MOA
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Stimulates pancreatic Beta cells to secrete insulin
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Sulfonylurea Adverse effects
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hypoglycemia, Take well known sulfonylureas 30 minutes prior to a meal
contraindicated if sulfa allergy |
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Diabinese generic
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Chlorpropamide brand
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Diabinese drug class
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sulfonlyurea
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Amaryl generic
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Glimpepiride brand
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Amaryl drug class
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sulfonylruea
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Glucotrol generic
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Glipizide brand
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Glucotrol drug class
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sulfonylurea
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Diabeta/Micronase generic
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Glyburide brand
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Glynase generic
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Glyburide micronized brand
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glyburide drug class
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sulfonylureas
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Prandin generic
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repaglinide brand
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Prandin drug class
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Meglitinides
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Starlix generic
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Nateglinide brand
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Starlix drug class
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Meglitinide
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Meglitinide adverse effects
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Hypoglycemia, Take 30 minutes before meals, weight gain
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Alpha-Glucosidease inhibitors Indications
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Type 2, type 1 as adjunct to insulin, not indicated in children, pregnant or breastfeeding
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Alpha glucosidase inhibitors MOA
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Delays carbohydrate metabolism and absorption
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Alpha glucosidase inhibitors ADEs
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Initial gas and diarrhea, Increases LFTs
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Alpha glucosidase inhibitors Monitoring
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LFTs every 3 months during first year of therapy
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Precose generic
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Acarbose Brand
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Glyset generic
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Miglitol Brand
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Precose drug class
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alpha glucosidase inhibitor
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Glyset drug class
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alpha glucosidase inhibitor
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Insulin sensitizers (Biguanide and Thiazolidinediones) Indications
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Type 2, type 1 insulin adjunct
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Glucophage MOA
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increases hepatic and peripheral insulin sensitivity and decreases hepatic glucose production
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Thiazolidinediones MOA
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increases skeletal muscle adipose tissue, and liver insulin sensitivity and decreses hepatic glucose production
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Glucophage ADEs
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May cause lactic acidosis (SCr men <1.5, women<1.4)
May cause weight loss GI discomfort or Diarrhea initially can lower B12 levels |
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Thiazolidinediones Counseling
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Take once or twice daily with or withiout food
Edema, anemia, wt. gain Not used in persons with ALT >2.5 |
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Metformin monitoring
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Renal and liver function tests
B12, Folic acid, CBC annually |
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Thiazolidinedione monitoring
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LFTs at baseline, every 2 months during first year then periodically
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Actos generic
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Pioglitazone brand
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Actos drug class
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Thiazolidinedione
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Avandia generic
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Rosiglitazone Brand
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Avandia drug class
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Thiazolidinedione
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Glucovance generic
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Glyburide/Metformin Brand
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Metaglip generic
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Glipizide/Metformin Brand
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Avandamet generic
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Rosiglitazone/Metformin Brand
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Avandia generic
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Rosiglitazone Brand
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Avandia drug class
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Thiazolidinedione
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Glucovance generic
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Glyburide/Metformin Brand
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Metaglip generic
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Glipizide/Metformin Brand
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Avandamet generic
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Rosiglitazone/Metformin Brand
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