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55 Cards in this Set

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Normal Fasting Glucose
70-110
A1C good control level
<6.5
BP goal in Diabetes
<130/80
Lipid goals in diabetes
LDL: <100, <70 in high risk
Triglycerides: <150
HDL: >40
Humalog
Lispro: rapid acting
Novolog
Aspart: Rapid acting
Humulin/Novolin R
Regular insulin: Short acting
Humulin/Novolin N
NPH: Intermediate acting
Lantus
Glargine: Long acting
Hypoglycemia characteristics
Sudden fatigue, tachycardia, sweating, confusion, headache
Ketoacidosis characteristics
Positive glycosuria and ketonuria, thirst, "Juicy Fruit" breath, rapid pulse, drowsiness, loss of appetite
Insulin Secretagugues (sulfonylureas and Meglitinides) Indications
Type 2 diabetes: Not in children, pregnant and lactating women or type 1
Insulin Secretagogues (sulfonylureas and Meglitinides) MOA
Stimulates pancreatic Beta cells to secrete insulin
Sulfonylurea Adverse effects
hypoglycemia, Take well known sulfonylureas 30 minutes prior to a meal
contraindicated if sulfa allergy
Diabinese generic
Chlorpropamide brand
Diabinese drug class
sulfonlyurea
Amaryl generic
Glimpepiride brand
Amaryl drug class
sulfonylruea
Glucotrol generic
Glipizide brand
Glucotrol drug class
sulfonylurea
Diabeta/Micronase generic
Glyburide brand
Glynase generic
Glyburide micronized brand
glyburide drug class
sulfonylureas
Prandin generic
repaglinide brand
Prandin drug class
Meglitinides
Starlix generic
Nateglinide brand
Starlix drug class
Meglitinide
Meglitinide adverse effects
Hypoglycemia, Take 30 minutes before meals, weight gain
Alpha-Glucosidease inhibitors Indications
Type 2, type 1 as adjunct to insulin, not indicated in children, pregnant or breastfeeding
Alpha glucosidase inhibitors MOA
Delays carbohydrate metabolism and absorption
Alpha glucosidase inhibitors ADEs
Initial gas and diarrhea, Increases LFTs
Alpha glucosidase inhibitors Monitoring
LFTs every 3 months during first year of therapy
Precose generic
Acarbose Brand
Glyset generic
Miglitol Brand
Precose drug class
alpha glucosidase inhibitor
Glyset drug class
alpha glucosidase inhibitor
Insulin sensitizers (Biguanide and Thiazolidinediones) Indications
Type 2, type 1 insulin adjunct
Glucophage MOA
increases hepatic and peripheral insulin sensitivity and decreases hepatic glucose production
Thiazolidinediones MOA
increases skeletal muscle adipose tissue, and liver insulin sensitivity and decreses hepatic glucose production
Glucophage ADEs
May cause lactic acidosis (SCr men <1.5, women<1.4)
May cause weight loss
GI discomfort or Diarrhea initially
can lower B12 levels
Thiazolidinediones Counseling
Take once or twice daily with or withiout food
Edema, anemia, wt. gain
Not used in persons with ALT >2.5
Metformin monitoring
Renal and liver function tests
B12, Folic acid, CBC annually
Thiazolidinedione monitoring
LFTs at baseline, every 2 months during first year then periodically
Actos generic
Pioglitazone brand
Actos drug class
Thiazolidinedione
Avandia generic
Rosiglitazone Brand
Avandia drug class
Thiazolidinedione
Glucovance generic
Glyburide/Metformin Brand
Metaglip generic
Glipizide/Metformin Brand
Avandamet generic
Rosiglitazone/Metformin Brand
Avandia generic
Rosiglitazone Brand
Avandia drug class
Thiazolidinedione
Glucovance generic
Glyburide/Metformin Brand
Metaglip generic
Glipizide/Metformin Brand
Avandamet generic
Rosiglitazone/Metformin Brand