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14 Cards in this Set
- Front
- Back
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Sulfonylureas
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Glipizide (Glucotrol)
Glimipermide (Amaryl) Glyburide (Micronase, DiaBeta) A1C = 1-2% |
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Glipizide Dose
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5 - 10 mg
(Give > 10 mL/min) |
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Glimepiride
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1-2 mg daily initial
1-4 mg/day maintenance max = 8 give if > 30 mL/min |
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Glyburide
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2.5 - 5 mg/day (hypoglycemic sensitivity--give 1.25 initial)
1.25 - 20/day give if > 30 mL/min |
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Glinides
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Prandin = Repaglinde
Starlix = Nateglinide 0.6-1% A1C decrease |
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Repaglinide = Prandin
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0.5, 1, 2 mg TID/QID
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Starlix = Nateglinide
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120 mg TID
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Biguanide (Metformin)
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500 mg - 1000 mg BID
A1C by 1.5-2% Lactic Acidosis: Poor Renal Function, Hepatic dysfunction, Alcohol, Radioconstrast Dye, Metically Managed CHF, Dehydration, Surgery C/I--Scr 1.4 (women) 1.5 (men), CrCl < 30, acute HF, metabolic acidosis, contrast dye, liver disease |
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Thiazoidinediones
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Acots: Pioglitazone
Avandia: Rosiglitazone A1C 1.5-2% increase weight, edema, increase LFT, anemia |
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Actos = Pioglitazone
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15-30 mg/day initial
45 mg/day max |
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Avandia = Rosiglitazone
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4 mg/day initial
8 mg/day max |
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GLP 1 Receptor Agonist
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Byetta = Exenatide
Victoza = Liralutide A1C = .5 -1.5% (if with metformin or sulfonylurea) |
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DPP IV Inhibitors
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Januvia Sitagliptin
Onglyza Saxagliptin 0.6-0.9% |
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Januvia
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100 mg daily
30-50 ml/min 50 mg daily <30 ml/min 25 daily |
