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25 Cards in this Set
- Front
- Back
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IL-1 |
Induces leukocyte adhesion to endothelial cells via P and E selectin, thus increasing vascular permeability. TNF also
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Which cytokine can increase the fibroblast synthesis of collagen? |
IL-1 |
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Which cytokine can increase and also decrease coagulation |
IL-1, TNF |
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Which is produced more? IL1 alpha or beta? |
Beta |
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IL 1 induces the proliferation of what cells |
Macrophage, lymphocytes, B cells |
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Which cytokines induces the secretion of acute phase proteins from the liver? |
IL1 and 6 |
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Which cytokines are pyrogenic |
IL1, 6, tNF |
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Can IL-1 trigger the sensation of pain? |
Yes, IL-1 causes vasodilation and hypotension |
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IL-1 can activate NK? |
Yes |
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IL 2 is secreted mainly by |
T helper 1 |
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Interleukins that activate NK cells |
IL 1, 2 |
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Causes B cell proliferation |
B cell |
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Interleukins that act as CSFs, inducing theEdifferentiation of hematopoietic cells |
IL-3, IL-7, GM-CSF |
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IL 3 is secreted by |
Basophils, Th1 , Th2 |
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Which inyerleukin antagonizes IFN gamma and IL 2? |
IL 4 |
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IL 4 is secreted by |
Th2, masf cell, DCs |
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IL 4 upregulates |
MHC class 2 expression |
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Which interleukin plays a signicant role in eosinophils |
IL 5 |
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IL 6 |
Pyrogen (intiates PGE2 synthesis in the hypithalamus, inducing fever), stimulates neutrophil synthesis in the bone marrow, synthesis of acute phase proteins, supports b cell growth |
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IL 7 |
Hematopoietic growth factor secreted by the stromal cells in the bone marrow and thymus. A lymohoid progenitor cell |
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Neutrophil chemotaxis inducer |
IL 8 |
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Angiogenesis promoter |
IL8 |
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Stimulates megakaryocyte maturation |
IL 11 |
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Hematopoietic factors |
IL 3, 5, 7,8,11 |
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NK activation |
IL 12 |
