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31 Cards in this Set

  • Front
  • Back

IL1a and B

Produced by macrophages and help in T cell activation and Macrophage activation

IL2 -T cell growth

Produced by T cells


Help Treg maintenance and function, T cell proliferation and differentiation

IL4

Produced by Th2 and mast cells.


Also priming cytokines for Th2 cells

IL5

Produced by mast cells and T cells.


Action to help eosinophil growth

IL6

Priming cytokine for Th17 cells.


Help in T and B cells growth and differentiation

IL9

Produced by Th9 cells.


Mast cell enhancing activity

IL10

Produced T helper 1,2,17 and Tregs, dendritic cells. It is a potent suppressor. Anti inflammatory

IL12

Produced my macrophages and dendritic cells. Activated NK cells, induced CD4+ T cells differentiation into th1

IL13

Produced by Th2 cells.


Help with B cell growth and differentiation and inhibits macrophages inflammatory cytokine production and Th1 cells.


induced allergy/asthma

IL16-

Produced by T cells mast cells and eosinophils


It is a chemoatrractant for Cd4 T cells, monocytes and eosinophils.

IL18

Produced my activated macrophages.


Induced infY production by T cells and NK cells promotes Th1 induction

IL19

Produced by monocytes


Induced IL6 and TNFa expresssion by monocytes

IL20

Produced by Th1. And monocytes

IL21

Produced my Tfh cells


Proliferation of T and B and NK cells

IL22

Produced by Th22 cells

IL23

Produced by dendritic cells and macrophages


Induceds proliferation of Th17 memory T cells and increase INF y production

IL25

Promotes Th2 cells


Promotes Th2 cytokine production

IL26

Produced by Th17 and NK cell


Pro inflammatory

IL27

Induced IL10

IL31

Produced by Th2


Pro inflammatory

IL32

Produced by Nk and T cells


Induced TNFa

IL33

Induced Th2 cytokines

IL34

Promotes growth and development of myeloid cells/osteoclasts

IL35

Produced by Tregs and B cells


Immunosuppressive

IL36 a B

Pro inflammatory stimulant of macrophages and dendritic cells

IL37

Suppressed dendritic cells/ monocytes production of IL 1,6, 12

TSLP

Stimulates hematopietic cells and dendritic cells to induce Th2 response

LIF -leukaemia inhibitory factor

Maintaining embryonic stem cells

INFy

Produced by T cells, NK cells and neutrophils and ILC1 intraepithelial lymphocytes.


Macrophages activation and increased expression of MHC molecules and processing components, suppressed Th2 and 17

M-CSF

Stimulates growth of cell monocytes lineage

G-CSF

Stimulates neutrophil development and differentiation