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31 Cards in this Set
- Front
- Back
IL1a and B |
Produced by macrophages and help in T cell activation and Macrophage activation |
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IL2 -T cell growth |
Produced by T cells Help Treg maintenance and function, T cell proliferation and differentiation |
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IL4 |
Produced by Th2 and mast cells. Also priming cytokines for Th2 cells |
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IL5 |
Produced by mast cells and T cells. Action to help eosinophil growth |
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IL6 |
Priming cytokine for Th17 cells. Help in T and B cells growth and differentiation |
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IL9 |
Produced by Th9 cells. Mast cell enhancing activity |
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IL10 |
Produced T helper 1,2,17 and Tregs, dendritic cells. It is a potent suppressor. Anti inflammatory |
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IL12 |
Produced my macrophages and dendritic cells. Activated NK cells, induced CD4+ T cells differentiation into th1 |
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IL13 |
Produced by Th2 cells. Help with B cell growth and differentiation and inhibits macrophages inflammatory cytokine production and Th1 cells. induced allergy/asthma |
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IL16- |
Produced by T cells mast cells and eosinophils It is a chemoatrractant for Cd4 T cells, monocytes and eosinophils. |
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IL18 |
Produced my activated macrophages. Induced infY production by T cells and NK cells promotes Th1 induction |
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IL19 |
Produced by monocytes Induced IL6 and TNFa expresssion by monocytes |
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IL20 |
Produced by Th1. And monocytes |
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IL21 |
Produced my Tfh cells Proliferation of T and B and NK cells |
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IL22 |
Produced by Th22 cells |
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IL23 |
Produced by dendritic cells and macrophages Induceds proliferation of Th17 memory T cells and increase INF y production |
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IL25 |
Promotes Th2 cells Promotes Th2 cytokine production |
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IL26 |
Produced by Th17 and NK cell Pro inflammatory |
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IL27 |
Induced IL10 |
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IL31 |
Produced by Th2 Pro inflammatory |
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IL32 |
Produced by Nk and T cells Induced TNFa |
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IL33 |
Induced Th2 cytokines |
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IL34 |
Promotes growth and development of myeloid cells/osteoclasts |
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IL35 |
Produced by Tregs and B cells Immunosuppressive |
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IL36 a B |
Pro inflammatory stimulant of macrophages and dendritic cells |
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IL37 |
Suppressed dendritic cells/ monocytes production of IL 1,6, 12 |
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TSLP |
Stimulates hematopietic cells and dendritic cells to induce Th2 response |
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LIF -leukaemia inhibitory factor |
Maintaining embryonic stem cells |
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INFy |
Produced by T cells, NK cells and neutrophils and ILC1 intraepithelial lymphocytes. Macrophages activation and increased expression of MHC molecules and processing components, suppressed Th2 and 17 |
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M-CSF |
Stimulates growth of cell monocytes lineage |
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G-CSF |
Stimulates neutrophil development and differentiation |