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38 Cards in this Set
- Front
- Back
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T or F. The liver is a metabolic hug
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TRUE
carbs, proteins, lipid storage |
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Is the liver endocrine or exocrine gland?
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both!
exocrine secretion of bilirubin and bile endocrine secretion of plasma proteins, coag factors, metal/lipid transport proteins, cholesterol |
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what cells do phagocytosis in the liver
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kupffer cells
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what are the three basic units of the liver
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classic lobule
portal lobule liver acinus |
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what makes up the portal canal
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portal triad + lymph vessels + autonomic nerves
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What makes up the portal triad
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hep portal vein
hep artery bile duct |
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def. the extensive meshwork between adjacent plates of hepatic cells
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liver sinusoids
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what do you find in the liver sinusoids
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kupffer cells
endothelial cells resident NK |
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def. perisinusoidal region where you find blood plasma but NOT RBC/s platelets
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space of disse
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what is another name for lipocytes
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stellate or ito cells
storage of Vit a |
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what are the sides of the hepatocytes
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two basal
two lateral two apical |
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which side of the hepatocyte borders neighbors and secretes endocrine products that enter the sinusoids
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lateral
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which side of the hepatocyte faces sinusoids and is responsible for endocrine uptake and function
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basal
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this side of the hepatoycte is for half of bile canaliculus and exocrine function
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apical
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Is bile exocrine or endocrine function?
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EXO
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what is th emost abundant protein syntehsized by hepatocytes
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albumin
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what organelle synthesizes and degrades glycogen
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SER
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what organelle converts alcohol to acetaldehyde and forms alc. DH
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peroxisomes
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what organelle stores iron
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lysosomes
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which surface has actin in adhesion belt of terminal web to move bile toward portal canal
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apical surface
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name the three models of liver function
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classic
portal acinar |
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which model emphasizes anatomy? exocrin fuction? blood supply?
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classic
portal acinar |
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which model is the zone model
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acinar
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which zone is at greatest risk of hypoxia and damage from toxic substnace leading to central necrosis
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zone 3 of acinar model
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what is secreted in the bile
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bile salts
pigments cholesterol phospholipids electrolytes |
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what emulsify lipids in the small intestine and keep cholesterol and Plipids in solution
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bile salts
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T or F. most bile salts are recycled by enterohepatic circulation
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true :)
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what are the layers of the gall bladder
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mucosa
muscularis externa fibrosa/serosa |
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what kind of cells are in the mucosa
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simple columnar with microvilli
underlying lamina propria |
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why do you know there is SM in the muscularis externa
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helps push bile to out
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what is the function of the gallbladder
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concentrate and store bile
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The liver is enclosed by a layer of _____ ______ CT
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dense irregular
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what collects from numerous cetnral veins and goes to hepatic vein
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sublobular vein
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where does nutrient rich venous blood fromthe portal vein mix with O2 rich blood from hepatic arteries
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in the sinusoids
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describe the endothelial cells at space of disse
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discontinuous
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the space of disse containes ____ which are composed of numerous droplets that store vit A
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lipocytes
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bile flows toward the _____ _____ where the bile duct is. The canals of _____ are lined with simple _____ epithelium and merge with bile ductules that drain into the bile ducts in the portal canals
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portal vein
hering cuboidal |
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the channels through which bile flows from the bile canaliculi to the gall bladder into the small intestine is called the _____ ______
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biliary tree
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