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19 Cards in this Set

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  • Back

Myosin heavy-chain (MHC) proteins

Can change from type IIx fibers to type IIa as a result of resistance training

Anabolic hormones

Hormones that promote tissue building (insulin, IGF's, testosterone, growth hormone)

Catabolic hormones

Degrade cell proteins to support glucose synthesis (cortisol, progesterone)

Lock-and-key-theory

States that a given hormone interacts with a specific receptor

Cross-reactivity

A given receptor partially interacts with hormones not specifically designed for it (i.e. allosteric binding)

Allosteric binding sites

Areas at which substances other than hormones can enhance or reduce cellular response to the primary hormone

Downregulation of receptor function

Inability for a hormone to interact with a receptor

Steroid hormones

-Produced by adrenal cortex and gonads
-Fat soluble


-Passively diffuse across sarcolemma of muscle

Hormone-receptor complex

Result of the binding of hormone and receptor

Polypeptide Hormones

-Composed of amino acids


-Includes GH and insulin


-Bind to receptors in blood or within cell membrane

Secondary messengers

Required by polypeptide hormones to cross cell membrane due to lack of fat-solubility

Primary anabolic hormones

Test, GH, IGF's are examples of:

Testosterone

Primary androgen hormone that interacts with skeletal muscle

Diurnal variations

Normal fluctuations of hormone levels throughout the day

Growth Hormone

-AKA somatotropin


-Secreted by pituitary gland


-Enhances cellular amino acid uptake and protein synth in skeletal muscle (with resistance training)

Insulin-Like Growth Factors

-Polypeptide hormones


-Secreted by liver after GH stimulates liver cell DNA to synthesize them


-In blood, travel bound to binding proteins


-Interact with receptors once they reach target tissue

Cortisol

-Adrenal hormone which acts as the primary signal hormone for carb metabolism and is related to glycogen stores in muscle
-Increases levels of proteolytic enzymes

Proteolytic enzymes

Enzymes which break down proteins

Catecholamines

-(epinephrine, norepinephrine, dopamine)


-Secreted by adrenal medulla


-Important for acute expression of strength and power


-Act as central motor stimulators and peripheral vascular dilators