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13 Cards in this Set

  • Front
  • Back

CN III, Oculomotor n.

-- oculomotor nucleus (midbrain, ventral to periaqueductal gray)


-> interpeduncular fossa -> lateral cavernous sinus


=> all extraocular mm., except for superior oblique & lateral rectus


=> levator palpebrae (elevator of the upper lid)




-- Edinger-Westphal nucleus (b/w CN III nuclei)


-> parasympathetic fibers -> ciliary ganglion


=> constrictor of the pupil & ciliary m. (constricts)

CN IV, Trochlear n.

-- trochlear nucleus - rostral pons (caudal midbrain; only CN exiting from dorsum of brainstem)


-> decussates (as only CN; long & thin)


-> ponto-mesenphalic jxn


-> lateral cavernous sinus


=> superior oblique m.

CN VI, Abducens n.

-- abducens nucleus - caudal pons (facial colliculus, floor of the 4th ventricle)


-> pontomedullary jxn -> dura, cavernous sinus


=> lateral rectus m.

Saccadic eye movement

= rapid eye movements to acquire new target


(~ most voluntary eye movements; blurred during movement)


- produced by CC or superior colliculus -> PPRF & rostral interstitial nuc.


- resting tone baseline -> burst -> movement -> new resting baseline


- delay ~200ms b/w burst & eye movement; head turns 20-40ms after


-> vestibular fb -> opposite, compensatory eye movement


- inhibited (/decrease from baseline) when moving in opposite direction


- microsaccades: prevent image from blanching by fading on retina

Horizontal conjugate gaze pwy

= 1D saccadic eye movement:


- R frontal eye field (A8, premotor C)


(-> (R superior colliculus) -X->


L PPRF (paramedian pontine reticular formation)


-> L CN VI


--> L lateral rectus m.


--> MLF -> R CN III -> R medial rectus m.


[frontal eye field => contralateral gaze]

Superior colliculus

Afferents: retina, inferior colliculus, SC, CC


Efferents: SC (tectospinal t.) & brainstem (tectoreticular t. - PPRF, midbrain RF)


=> adjusts head & eye towards a stimulus


- visual field map representation


- inward flow in information (visual -> motor l.)

Internuclear opthalmoplegia

- results from dmg to MLF b/w CN IV & III nuclei


=> eye moving laterally is NOT followed by medial movement of the other eye

Vertical gaze pwy

Diffuse CC A's


-> rostral interstitial nucleus, MLF - rostral midbrain (vertical gaze center) ->


upgaze: (-> posterior commissure) -> CN III, IV

VOR (Vestibulo-Ocular Reflex) pwy

- produces non-saccadic eye movements:


CN VIII (-> Flocculus) -> Vestibular nucleus


-> CN VI & PPRF -> MLF -> CN III, IV




- used in compensation for head movement (& similar pwy: tracking a moving object)


- when damaged => nystagmus (drift + saccade)

Smooth pursuit/tracking pwy

Occipital eye field (CC)


(-> frontal eye field) -> pontine nuclei


-> middle c. peduncle -X-> flocculus (contral.)


-> inferior c. peduncle -X-> vestibular complex


-/-> CN VI, PPRF (bilateral) -> MLF -> CN III, IV


- stimulus = "retinal slip"


- fixation & optokinetic reflexes (lost in movements towards a CC lesion)

Vergence reflexes

- focus on near objects


- controlled by occipital cortex projections


-> vergence center (RF, mesencephalon)


- wired in parallel w/ accommodation (pupil, lens)

Pupilary light reflex

CN II -> pretectum (-> posterior commissure)


-/-> Edinger-Westphal nucleus -> CN III


-> pupillary constriction [consensual]

Nystagmus

- Pendular (symmetrical): not due to CNS/vestibular dmg




- Jerk (fast & slow components) ~ vestibular system dmg / drugs & toxins


-- slow ~ vestibular activity imbalance


-- fast ~ compensation due to CC awareness


- Horizontal: inner ear dmg


- Down-beating: caudal brainstem dmg