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84 Cards in this Set

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Form of respiratory infection that fills alveoli of the lungs with pus and fluid making breathing painful and limits oxygen take

Pneumonia

Single largest infectious cause of death in children worldwide; Can prevent with simple intervention and low cost medication

Pneumonia

Most common bacteria cause of Pneumonia

Streptococcus Pneumoniae

Second most common bacterial cause of Pneumonia

Haemophilus Influenza Type B (Hib)

Most common viral cause of Pneumonia

Respiratory Syncytial Virus (RSV)

Fungal cause in infants with HIV

Pneumocystis Jirovecii

Causative agents of Pneumonia

* Steptococcus Pneumoniae


* Haemophilus Influenza Type B


* Respiratory Syncytial Virus


* Pneumocytis Jirovecii

Transmission of Pneumonia

* Droplet


* Airborne


* Through blood during and shortly after birth

Signs and Symptoms of Pneumonia

* Cough


* Fever


* Convulsion


* Unconciousness


* Hypothermia


* Wheezing (Most common)

Risk Factors of Pneumonia

* Infants


* Elderly


* Air Pollution


* Smoking


* Immunocompromised Individuals

Prevention and Treatment of Pneumonia

* Adequate Nutrition


* Breastfeeding for 6 months


* Good Hygiene


* Antibiotics and Bed Rest


* Immunization

The passage of three or more loose or liquids stools per day

Diarrheal Disease

Second leading cause of death in childreb under 5 years old

Diarrheal Disease

Can deplete the body of water and salts necessary for survival; Dehydration and sepsis are possible cause of death

Diarrheal Disease

Clinical Types of Diarrhea

* Acute Water Diarrhea - lasts several hours or days


* Acute Bloody Diarrhea - also called dysentery


* Chronic Diarrhea - last 14 days or longer

Causative Agents of Diarrheal Disease

* Escherichia Coli


* Shigella spp.


* Rotavirus - gastroenteritis in child


* Norwalk Virus - " in adult


* Cryptosporidium Parvum

Transmission of Diarrheal Disease

* Ingestion of contaminated water


* Poor personal hygiene


* Fish and seafood from polluted water

Signs and Symptoms of Diarrheal Disease

* Liquid stools per day


* Dehydration (Severe threat)

Lethargy, unconciousness, sunken eyes and skin pinch goes back slowly

Severe Dehydration

Restlessness, irratability, sunken eyes and polydypsia

Slight Dehydration

Excessive thirst or drinking

Polydypsia

Risk Factors of Diarrheal Disease

* Unclean water supply


* Improper sewage disposal

Prevention and Treatment of Diarrheal Disease

* Sanitation and Personal Hygiene


* Safe drinking water


* Handwashing


* Rotavirus Vaccination


* Health Vaccination


* Rehydration and Medication

Acute respiratory infection caused by influenza virus which circulate in all parts of the world

Influenza

Severity varies from asymptomatic to fatal disease; May result to complications and even death in some groups of individuals

Influenza

Type of I influenza virus responsible for most epidemics

Type A

Agglutinates RBCs

16 Hemagglutinin (HA)

Release influenza virua from the cell after replication

9 Neuraminidase (NA)

Type of influenza virus sometimes cayse epidemics

Type B

Type of influenza virus that causes mild illness

Type C

Type of influenza virus primarily affect cattle

Type D

Transmission of Influenza

* Airborne


* Droplet


* Fomites

* A (H1N1)


* A (H3N2)

Swine Flu

* A (H5N1)


* A (H7N9)

Bird/Avian Flu

Signs and Symptoms of Influenza

* Fever


* Dry cough and Sore Throat


* Headache


* Body Malaise


* Joint Pain


* Runny Nose

Risk Factor of Influenza

* Crowdee areas


* Health care facilities

Prone to complication of Influenza

* Pregant women


* Infants


* Elderly


* Immunocompromised Individual

Prevention and Treatment of Influenza

* Handwashing


* Covering mouth when coughing


* Symptomatoc treatment


* Neuraminidase inhibitors, antiviral drugs


* Self limiting disease

A bacterial infection of the lungs

Tuberculosis

One of the top 10 causew of death worldwide and is a leading killer of HIV-positive people

Tuberculosis

Causative Agent or Tuberculosis

* Mycobacterium Tuberculosis


* Koch's Bacillus

Cells contains mycolic acid


* Grows slowlt culture


* Resistance to antomicrobials dessication


* Protection from phagocytosis

Koch's Bacillus

Transmission od Tuberculosis

* Airborne


* Fomites

Signs and Symptoms of Tuberculosis

* Cough


* Chest pain


* Weaknese


* Weight loss


* Fever and night sweats

Diagnosed by sputum smears

Tuberculosis

Risk Factor of TB

* All age group


* Increased in immunocomprising conditions


* Tobacco smoking


* People infected with HIV

Prevention and Treatment of Tuberculosis

* 6 months course of 4 antimicrobial drugs


* DOTS

Resistance to isoniazid and rifampicin, two of the most potent first line anti-TB drugs

MDRTB (Multi-drug Resistant Tuberculosis)

Do not respond to second line drugs, no other treatment options

XDRTB (Extensively Drug Resistance Tuberculosis)

First Line Drugs of TB

* Pyrazinamide


* Rifampicin


* Isoniazid


* Streptomycin


* Ethambutol

Second line Drugs of TB

* Ciprofloxacin


* Cycloserine


* Capreomycin


* Ofloxacin


* Kanamycin


* Ethionamide


* Rifabutin

The immune system is targeted and weakened, ultimately leading to immunocompromised status

HIV (Human Immunodeficiency Virus)

The risk of dying is not due to virus itself, but instead due to opportunistic infections that are normally regulated by a healthy immune system

HIV

Causative Agent of HIV

* Targets CD4 cells


* Completion of viral replication leads to cell lysis

Cluster of Differentiation 4; Found on thw WBC that fight off pathogen; Essentially concentrated on T-helper cells which detect the presence of pathogens in the body and activate immune system once an infection is detected

CD4

CD4 + T-cells normal value

500 - 1500 cells/uL

CD4 + T-cells value of person with AIDS

<200/uL

Transmission of HIV

* Perinatal


* Percutaneoua


* Permucosal


* Blood-borne


* Body fluids except swear, saliva, urine and tears

Signs and Symptoms of HIV

* Early Stage - Flu-like symptoms, rash, and sore throat



* Intermediate Stage - Swollen lymph nodes, weight loss, fever, diarrhea, cough



*Late Stage - TB, cryptoccocal menigitis, severe bacterial infections, kaposi's sarcoma

Risk Factor of HIV

* Unprotected anal or vaginal sex


* Having another underlying STI/STD


* Sharing contaminated needles and syringes


* Unsafe blood transfusion and tissue transplants


* Accidental needle stick injury


* Use of unsterilized contaminated surgical equipment

Prevention and Treatment of HIV

* Use of condoms


* Testing and counselling


* Male circumcision


* Pre and Post exposure prophylaxis


* Anti-retroviral theraphy


* Elimination of Mother-to-Child Transmission

A blood borne Protozoan parasite that causes a life threatening disease; Leading parasitic disease that causes mortality worldwide; Characterized by recurrent febrile episodes

Malaria

Causative Agent of Malaria

* P. Falciparum - common in PH


* P. Vivax - common in the world


* P. Ovale


* P. malariae

Transmission of Malaria

* Vectorborne


* Through the bite of the female Anopheles mosquito

Signs and Symptoms of Malaria

* Fever, headache, chills


* Severe anemia


*Respiratory distress due to metabolic acidosis


* Cerebral malaria


*Multi-organ development

Risk Factor of Malaria

* Endemic areas


* Immunocompromised individuals


* Infants


* Pregnant women


* Non-immune travelers

Prevention and Treatment of Malaria

* Vector control


* Anti-malaria drugs


* Vaccination

A viral febrile infection that causes a flu-like illness; Leading cause of serious illness and death among children; Occasionally develops into lethal complications

Dengue

Causative Agent of Dengue

* High degree of tropism for bone marrow precursor cells


* Breakbone fever - followed by myalgia and deep bone pain


*Recovery from infection by ine sereotype provides lifelong immunity to that sereotype


* Severe dengue syndromes occurs

Transmission of Dengue

* Vectorborne


* Bite of female Aedes mosquito

Signs and Symptoms of Dengue

* Flu-like signs and symptoms


* Headache


* Muscle and joints pain


* Nausea


* Vomiting


* Swollen glands or rashes

Risk Factors of Dengue

* Uncovered water supply


* Poor environmental sanitation

Prevention and Treatment of Dengue

* Vaccination


* Vector control


* Proper management of water supply


* Self-limiting disease

General term used to denote infection of dengue, influenza, chikungunya, hepatitis A, leptospirosis, rickettsia, typhoid fever

Acute Febrile Illness

Viral disease transmitted to humans by infected mosquitosles such as Aedes Aegypti and Aedes Albopictus; There's no known cure; Symptomatic treatment

Chikungunya

Viral liver disease transmitted through ingestion of contaminated food and water; Fecal-oral transmission; Prevented by proper sanitation and vaccines

Hepatitis A

A bacterial disease that affects both humans and animals; Transmission via direct contact with the urine of infected animals; Bacteria enter the body through mucous membranes of mouth, nose, and eyes or through cuts and abrasions of the skin

Leptospirosis

A bacterial infection transmitted by the bite of lice, ticks, fleas and mites

Rickettsia

A life-threatening bacterial infection caused by Salmonella typhi; Fecal-oral transmission; Treated with antibiotics; Prevented by vaccine and good hygiene

Typhoid Fever

Most common causes of both illness and mortality in children

Acute Respiratory Tract Infection

Causative Agent of URTI

* Rhinitis


* Acute Pharyngitis

Causative Agent of LRTI

* Pneumonia


* Atypical Pneumonia


* Bronchiolitis

Transmission of Acute Respiratort Tract Infection

* Airborne


* Droplet


* Fomites

Prevention of ARTI

* Immunization


* Early diagnosis and treatment


* Improvements in nutrition


* Safer environments