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95 Cards in this Set

  • Front
  • Back
What brain regions comprise the cerebral cortex?
1. Frontal lobe
2. Parietal lobe
3. Occipital lobe
4. Temporal lobe
5. Wernicke's area
6. Broca's area
What is the purpose of Wernicke's area?
Comprehension of speech
What is the purpose of Broca's area?
Formation of speech
What are the basal ganglia responsible for?
Modify movement & autonomic motor function
What does the thalamus do?
Processes sensory impulses and relays them to the cerebral cortex
What does the hypothalamus do?
1. Maintains homeostasis.
2. Regulates temperature, heart rate, and BP.
3. Affects the endocrine system
4. Governs emotional behavior such as anger and sex drive
5. Endocrine function --> hormones secreted by the hypothalamus act directly on the pituitary
What is the brainstem responsible for?
Life-sustaining activities

Oldest part of the brain
What is the cerebellum responsible for?
Coordinates movement and keeps body upright in space
What are the three major motor pathways?
1. Corticospinal (or pyramidal) tract
2. Extrapyramidal tracts
3. Cerebellar system
What does the corticospinal tract do?
Controls voluntary movement, particularly skilled and discrete movements (e.g., writing)
What does the extrapyramidal tract do?
Controls voluntary movement, particularly gross movement (e.g., walking). Also affects tone of muscles.
** most fibers cross to opposite side
What does the cerebellar system do?
1. Coordinates movement
2. Helps control posture
3. Maintains equilibrium/proprioception
What is the pathway of information for motor tracts?
CNS (upper motor neurons) --> PNS (lower motor neurons)
What is the pathway of information for sensory tracts?
PNS (lower motor neurons) --> CNS (upper motor neurons)
**2 major pathways
What are the two major sensory pathways?
1. Spinothalamic tract
2. Posterior (dorsal) column tract
What is the spinothalamic tract responsible for? Pathway?
Sensation of:
1. pain
2. temperature
3. crude/light touch

*Fibers travel to thalamus, synapse on secondary neuron, then travel to cortex.
--> thalamus perceives crude/general sensation
--> sensory cortex interprets/fully perceives what was felt
What is the posterior column tract responsible for? Pathway?
Sense of:
1. proprioception (self)
2. vibrations
3. fine, localized touch

*Fibers travel to medulla, cross over & synapse onto secondary neuron, then travel to thalamus.
Where do cranial nerves II through XII arise from?
diencephalon and brainstem
(CN 1 is a fiber tract)
What is the composition of spinal nerves?
peripheral nerve fibers are both:
- sensory (dorsal)
- motor (ventral)
What areas of the spine do spinal nerves arise from and how many pairs arise from each section?
31 pairs of spinal nerves:
- 8 cervical pairs
- 12 thoracic
- 5 lumbar
- 5 sacral
- 1 coccygeal
What is a deep tendon reflex?
Involuntary, stereotypical response, relayed over both CNS & PNS. (1 synapse)
--> in order to elicit, you must tap tendon over partially stretched muscle
How many neurons are involved in a reflex reaction?
As few as two neurons -- one sensory and one motor.
5 requirements for a reflex arc?
1. Intact sensory neuron
2. Intact synapse
3. Intact motor neuron
4. Intact neuromuscular junction
5. Intact muscle
Spinal nerves involved in tricep reflex?
C6 & C7
Spinal nerves involved in plantar reflex?
Lumbar 5 & sacral 1
Spinal nerve involved in achilles reflex?
sacral 1
Spinal nerves involved in patellar reflex?
Lumbar 2, 3, and 4
Spinal nerves involved in brachioradialis reflex?
C5 & C6
Spinal nerves involved in the bicep reflex?
C5 & C6
What 12 items should you ask when obtaining a health history for the neurological system?
1. Headache
2. Head injury
3. Dizziness/Vertigo
4. Seizures
5. Tremors
6. Weakness, any part of the body
7. Incoordination (e.g., falling to one side)
8. Numbness or tingling
9. Difficulty swallowing (dysphagia)
10. Difficulty speaking (aphasia)
11. Significant past history (e.g., meningitis, stroke)
12. Environmental/occupational hazards (e.g., exposure to lead or insecticides, mind-altering drugs, alcohol intake)
What are the seven components of a physical exam for the neurological system?
1. Mental status
2. Cranial nerves
3. Motor
4. Sensory
5. Coordination
6. Romberg/gait
7. Deep tendon reflexes
How could you describe your patient's level of consciousness?
1. Alert
2. Lethargic: appears drowsy, still responds to stimuli
3. Obtunded: opens eyes, slow response, confusion
4. Stuporous: only awakened by painful stimuli
5. Comatose: completely unarousable
What is the order of loss of orientation?
Time is the first to go, then place, and lastly person
How can you assess attention?
1. Ask patient to repeat months of the year backward
2. Give patient a list of numbers and ask her to repeat back (use a phone number but do not speak it like a phone number). Being able to remember 6 or 7 numbers forward is normal, remembering 4 of the numbers backward is normal
What should you evaluate with the patient's language?
1. Fluency of speech
2. Any hesitancy
3. Does the speech make sense?
What are the three different levels of memory?
1. Immediate recall
2. Short-term (3-5 minutes later)
3. Long-term
How do you test CN I (olfactory)?
Have patient smell a familiar scent (e.g., cloves, coffee, soap, or vanilla). Patient should perceive odor and can often identify it.
Why should you not use ammonia for the olfactory test?
affects CN V
What are some possible causes of loss of smell?
Nasal disease, head trauma, smoking, aging, and use of cocaine
What are the tests for CN II (optic nerve)?
1. Visual acuity (Snellen chart)
2. Visual fields by confrontation
3. Pupillary reactions to light
4. Pupillary reactions to accommodation
5. Examine the optic fundi (using ophthalmoscope)
What does the pupillary light reflex test?
Direct and consensual pupillary constriction

CN II (optic nerve) receives the sensory input and sends it to the brain. The motor response comes back through CN III (oculomotor) and causes pupil constriction.
What are the three regions of sensory innervation for CN V (trigeminal)?
1. Ophthalmic
2. Maxillary
3. Mandibular
What effect does a peripheral injury to CN VII (facial nerve) cause?
Bell's palsy

peripheral injury = damage to FULL side of face on the SAME SIDE of the lesion.

Flat nasolabial fold, cannot raise eyebrow, cannot close eye, drooping lips on that side.
What effect does a central lesion of CN VII (facial nerve) cause?
Stroke (CVA) --> lesion in cortex

Lower part of face = controlled by upper motor neurons that CROSS OVER --> so when damage occurs, the lower face is paralyzed (i.e., central lesion in CN VII in left hemisphere would result in paralysis of the lower face on the right side) --> only HALF of OPPOSITE side of face affected

Flat nasolabial fold on side opposite of lesion. Can open and shut eyes, raise eyebrows (wrinkle forehead).
How do you test CN VIII (vestibulocochlear)?
1. Cochlear portion: finger rub test
2. Vestibular portion: Romberg test
How do you test CN IX (glossopharyngeal) and CN X (vagus)?
- AxO patient --> tongue depressor & have them say "ahh"

- comatose patient --> test gag reflex
What two muscles are you assessing when you perform the test for CN XI (accessory nerve)?
1. Trapezius (patient shrugs shoulders against resistance)
2. Sternocleidomastoid (patient pushes face against resistance)
What are you looking for when you test CN XII (hypoglossal)?
With the tongue protruded, you are looking for asymmetry, atrophy, or deviation from midline.

When you ask the patient to move her tongue from side to side, you are looking for symmetry of movement.
What should you look for when assessing the size of the patient's muscles?
Pay attention to bilateral symmetry, particularly in the hands.
What is atrophy of muscle? What might it indicate?
Atrophy is abnormally small muscles; loss of muscle bulk.

Possible causes: disuse, injury, lower motor neuron problem, muscle disease
What is hypertrophy of muscle? What causes it?
Increase in muscle bulk with corresponding increase in strength.

Caused by isometric exercises.
What is muscle tone?
Slight residual tension of the muscle when it is voluntarily relaxed.
How can you assess muscle tone?
Ask patient to relax and perform passive ROM.
What are some possible causes of muscle flaccidity?
Polio, early stage of stroke (progresses to spasticity), lower neuromuscular disease
What are some possible causes of muscle spasticity?
Injury to corticospinal tract, later stages of stroke
What is muscle spasticity?
Increased resistance that worsens at the extremes of ROM.

Increases with rapid movement.
What is muscle rigidity?
Increased resistance throughout the ROM in both directions.

cogwheel rigidity = little jerks, seen in Parkinson's
lead pipe rigidity = unbendable & rigid
What are some causes of muscle rigidity?
Damage to extrapyramidal tract, Parkinson's
What are the three different types of involuntary movements?
1. Tremors
2. Fasciculations
3. Tics
What are the two types of tremors?
1. Parkinson's tremors ("pill rolling tremor" --> happens passively)
2. Intention tremors (occur with task --> e.g., pouring water into glass)
What are fasciculations?
Rapid twitching of resting muscle
What is a tic?
Repetitive twitching at inappropriate time (psychiatric or neurologic etiology)
What are the three components for assessing the spinothalamic tract?
1. Pain
2. Temperature
3. Light or crude touch
When do you test sensation of temperature?
when pt doesn't pass sense of pain test
What are the three tests for assessing the posterior column tract?
1. Vibration
2. Proprioception
3. Tactile discrimination
If vibration can be felt distally (on the toe or thumb), what does that mean?
The vibration would also be felt further up (proximally).
What disease causes loss of vibratory sense?
Diabetes --> vibratory sense is first lost in the feet
What is stereognosis?
Ability to identify an object by feeling it.

Have patient close eyes and hand him a familiar object to identify.
What is graphesthesia?
Number identification

Have patient close eyes. "Draw" a number on the patient's palm and ask him to identify it.
How do you test two-point discrimination?
Have patient close eyes. First see if patient can identify two simultaneous touches. Next, bring the two points closer and closer together until patient can no longer distinguish them as separate.
What does extinction test for?
Sensation on the left and right sides.

Have patient close eyes. Simultaneously touch the same areas on both sides of the body (e.g., right and left shoulders). Ask patient where she felt your touch -- normally both stimuli are felt.
What are the tests for coordination and skilled movement?
1. Rapid alternating movements
2. Point-to-point movements
What is an abnormal result of the rapid alternating movement tests?
Dysdiadochokinesia: inability to arrest abruptly one motor impulse and substitute its opposite
What are the tests for point-to-point movements?
1. Finger-to-finger test
2. Finger-to-nose test
3. Heel-to-shin test
What is dysergia?
Improper coordinated function of given muscle groups
What is dysmetria?
Inability to gauge properly the distance between two points or objects
What is an abnormal response to the heel-to-shin test? What causes it?
The heel will bounce all over the place. Evident in a patient with multiple sclerosis.
How is the gait of a Parkinson's patient different?
Steps are short and shuffling. Less arm swinging. Patient turns around stiffly (turn on point), cannot spin on pivot.
Why would tandem walking be used after assessing gait?
It may reveal an ataxia not obvious in the assessment of the gait.

Ataxic gait = a gait that lacks coordination, with reeling and instability. Feet are planted far apart.
What is a positive Romberg test?
The patient stumbles when she has to stand upright, feet together, with eyes closed.

A little swaying is normal and does not count as a positive Romberg sign.
What is a positive pronator drift test? What might cause it?
The test is positive if the patient's arm moves downward and the forearm pronates.

Pronator drift may be the result of stroke.
What side of the hammer do you use for direct contact with tendons?
Flat side of hammer
What side of the hammer do you use for indirect contact (hitting your thumb) with tendons?
Pointed side of hammer.
What is the grading for tendon reflexes?
0 = no response
1+ = decreased reflex
2+ = normal
3+ = brisk, may be normal or abnormal
4+ = brisk, abnormal; test for clonus
Why would you use reinforcement when testing deep tendon reflexes?
reinforcement = having them grip fingers and pull apart

Used if a patient's reflexes are symmetrically diminished or absent. The isometric contraction of other muscles for up to 10 seconds may increase reflex activity.
What are the superficial reflexes we test for?
1. Abdominal reflex
2. Cremasteric reflex
3. Plantar reflex
What is an abnormal plantar reflex response?
Babinski's: toes curl up

(+) Babinski --> upgoing big toe & toes flex back
Possible causes: upper motor neuron problem; alcohol/drugs; can occur during seizure

Positive Babinski's test is normal in children under 2 years old
What is clonus? How do you test for it?
Rhythmic oscillations between dorsiflexion and plantar flexion --> abnormal finding

to test: move pt's foot between dorsiflexion and plantar flexion while lying down and watch for oscillation
What would happen if you damaged wernicke's area in dominant hemisphere?
wernicke's area is associated with auditory reception, so w/ damage --> you can hear but can't comprehend what you're hearing (can't make sense of language)
What would happen if you damaged broca's area in dominant hemisphere?
broca's area is associated with speech formation, so damage here --> you know what want to say but you can't vocalize/form the words
Which side of the brain is dominant in most people?
95% of people's left side of brain is dominant
spinal nerves that innervate arms
cervical spinal nerves
spinal nerves that innervate legs
lumbar spinal nerves
numbness in arms vs numbness in legs
numbness in arms = probably a cervical spinal nerve problem

numbness in legs = probably a lumbar spinal nerve problem
lower motor neuron disease vs upper motor neuron disease
lower motor neuron disease = increased tone (spasticity, rigidity)

lower motor neuron disease = decreased tone (flaccidity)