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25 Cards in this Set

  • Front
  • Back

Blood Composition

Plasma


Erythrocytes (red blood cells)


Leukocytes (white blood cells)


Thrombocytes(platelets)

Functions of Blood

Transport (gases, wastes, nutrients)


Clotting (to seal injuries)


Infection Fighting


Communication (hormones)

Leukocyte Types

Phagocytes (swallow invading microbes to destroy them)


Lymphocytes (produce antibodies that are used to identify and bind to microbes

Arteries

Carry blood away from the heart


Thick walled


Elastic


Lining smooth for flow


Muscular help pump


High blood pressure and fast flowing

Capillaries

Diffusion of waste in and out of the blood


High to low pressure and slow flowing

Veins

Take blood to heart from capillaries


Veins have valves


>prevent back-flow


Thinner walls than arteries


Low pressure and slow flowing against gravity

Clot formation

1. Platelets clump ya the site of the puncture and partially seal the leak


2. Platelets and injured tissue release the enzyme prothrombin activator that changes pro=>thrombin


3. Thrombin acts as an enzyme and serves how short amino acid chains from each fibrinogen molecule


4. These activated chains join and to end to form long ends of fibrin


5. Fibrin threads entangle red cells and platelets in the damaged area and form the framework of the clot

Front (Term)

P = superior Vena Cava (upper body)


Q = right atrium (blue)


R = right ventricle (blue)


S = pulmonary artery (blue)


T = pulmonary vein (red)


U = left atrium (red)


V = left ventricle (red)


W = Aorta (red)


AV valve between Q and R + U and V


Semi lunar between R and S + V W

Heartbeat

Systole = contraction of ventricles


Diastole = relaxation of the ventricles


Heart beats by itself (intrinsic) <= nodal tissue

Sinoatrial Node

SA pacemaker


Located in upper back wall of the right atrium


Indicates beat by sending out signal automatically about every .85s to make atria contract

AV Node

Found at the base of right atrium


When pulse sent out by SA node reaches AVnide it sends out signal along conducting fibres (Purkinje)

Heart Rate Nervous Control

Medulla oblongata. Speed up or slow downbeat according to stimuli received by the Autonomic Nervous System


Speed up = Adrenaline, low blood pressure/oxygen/pH


Slow down = High blood pressure/oxygen/pH

Coronary Arteries and Viens

Supply blood to the heart


Branch off aorta above the semilunar valve


Coronary veins empty to right atrium


Coronary arteries become plugged(Cholesterol) = heart attack

Hypotension

Low blood pressure


>Dehydration


>Bleeding


>Organ inflammation


>Heart problems



Hypertension

High blood pressure


>Smoking


>Obesity


>Diabetes


>Lack of physical activity


>Sodium and salt sensitivity


>Low calcium, magnesium, potassium


>Stress


>Alcohol


>Diet(High cholesterol)


>Aging


>Drugs

Pathogen

An organism or virus(biological agent) that can cause disease


>Bacteria, fungus, protist nematode



Antibiotics

Block metabolic pathways in bacteria but not eukaryotic cells


>Cell wall formation


>70 ribosomes used in protein synthesis


>Bacteria specific enzymes involved with metabolism

Bacteriostatic

Stop further growth but can't kill existing cells

Bacteriocidal

Kills microbes

Viruses and antibodies

Only reproduce using host cell metabolic pathways




Only the specific anti-viral agent will treat it

Non-specific Immunity

Physical Barriers


>Skin


>Lungs


>Cilia


Lysozyme


>Pathogens gone


pH


>Not good for things


Fatty acids


Sweat and Saliva


>keep things in check with agents


Phagocytes


>Whiteblood cells


Swelling


>Histamine => dilute toxins


Fever


>^temp = not good

Leukocyte Types

Phagocytes


>seek invaders and destroy


Lymphocytes


>Identify and produce antibodies

Specific Immunity

Macrophages


>Eat foreign pathogen and display antigens in surface


T cell lymphocytes


>match=activation of Thymus gland(T cell maker)


T cell protein => B cells


>Makes antibodies against antigens


B cell lymphocytes secretes plasma cells


>long lasting memory cells


Antibodies hug antigens and


>aggluates cells together


>Yo phagocytes eat us


>Can't enter cells

Passive VS Active Immunity

Passive = Needs another organisms antibodies




Active = Immune response => memory cells => longterm immunity

HIV Infection

HIV targets helper T lymphocytes which regulate adaptive immune system


Virus reproduces slowly


Virus reactivates and destroys T cells


Reduced immunity


Opportunistic infections