Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
26 Cards in this Set
- Front
- Back
|
Emphysema is a decrease in |
Alpha 1 |
|
|
Decreased albumin, increased alpha 2 and beta |
Nephrotic syndrome |
|
|
Beta gamma bridging |
Cirrhosis |
|
|
Iron deficiency marker |
Beta is high due to transferrin |
|
|
Fibrinogen band found in |
Beta (between beta and gamma) |
|
|
Small band in alpha 2 |
Hemoglobin from hemolysis is complexed to haptoglobin |
|
|
Wilson’s disease (Kayseri Fisher ring) |
Low Ceruplasmin, alpha 2 |
|
|
Nephrotic syndrome |
10 fold elevation in alpha 2 |
|
|
M spike |
Monoclonal gammopathy (sharp peak) |
|
|
How does capillary electrophoresis differ from normal electrophoresis |
Result is not permanent and proteins migrate in the opposite direction |
|
|
How does iso electric focusing work |
Compound stops where there is no longer an electric charge (has different pH points ) |
|
|
Voltammetry measures |
Current |
|
|
Potentiometery measure |
Voltage |
|
|
Amperometery measures |
Current |
|
|
Coulometry measures |
Charge |
|
|
Malnutrition marker |
Prealbumin |
|
|
Free light chains or bence Jones protein leads to what |
End stage renal failure |
|
|
what conditions indicate urine IFE |
serum SPE band > 30 g/L Serum IFE monoclonal protein found serum hypogammaglobulinemia |
|
|
what do we see in multiple myeloma |
Bone pain, elevated calcium, anemia, renal failure |
|
|
a MM diagnosis can be made when two of three are present, what are they |
paraprotein >30 g/L >10% plasma cells destruction of bone marrow |
|
|
MM is most associated with? |
IgG and IgA, also sometimes FLC only |
|
|
MM with no free light chain and no bone lesions with plasma cells less than 10% is? |
monoclonal gammopathy of undetermined significance MGUS |
|
|
waldenstroms macroglobulinemia is associated with? |
IgM paraproteins, greater than 30 g/L |
|
|
oligoclonal banding is seen in |
gamma region of multiple sclerosis patients |
|
|
What causes oligoclonal banding at the gamma region for MS? |
IgG locally produced in the SF |
|
|
what is the desired SF/serum albumin index |
less than 9, indicates healthy blood brain barrier |
