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17 Cards in this Set
- Front
- Back
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Achalasia |
A rare disorder making it difficult to pass food into the stomach. |
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Brady-Kinesia |
Slow Movements |
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Blood-Brain Barrier (BBB) |
its a mesh work of tightly packed cells in the calls of the brains capillaries that screen out certain substances. this mesh work prohibits large and potentially dangerous molecules from crossing over into the brain. |
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Choreiform Movements |
Repetitive and rapid Jerky, involuntary movements that appears to be well coordinated and is often seen in Huntington disease. |
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On-Off Phenomenon |
Occurs in patients taking Levedopa. In this condition the patient may suddenly alternated between improved clinical status to loss of all therapeutic effects. |
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Parkinsonism |
Refers to a group of symptoms involving movement, (tremors, rigidity, and slow movements AKA Bradykinesia) |
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Parkinson's Disease |
Parkinson's Disease is the most common form of Parkinsonism. It is progressive and worsens over time. Speech becomes slurred, the face takes on a mask-like and emotionless expression and the patient may have difficulty swallowing and chewing. the patients gait may become unseady and shuffled, with the upper part of the body bent forward. |
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Anti-Parkinsonism Drugs |
They either supplement the Dopamine in the brain or block excessive Acetylcholine (Ach) so that better transmission of nerve impulses occurs. |
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Dopaminergic Agent |
Monoamine oxidase inhibitors (MAOIs) and dopamine receptor agonist) |
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Dopaminergic Drugs |
Amantidine Parlodel Sinemet Caridopa/Levedopa (synemet) |
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whats the purpose/actions of a dopaminergic drug |
to make more dopamine available. |
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Purpose: Levedopa, Dopamine, Carbidopa |
levedopa is found in plant. dopamine is a form of levedopa that can cross the BBB only in small quantities. when is crosses it gets combined with carbidopa which in results makes more levedopa available to the brain. |
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Bromocriptine or Parlodel agonist |
They stimulate the dopamine receptors |
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amantadine (symmetrel) |
make more of the dopamine available at the receptor site. |
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rasagiline (azilect) and selegeline (eldepryl) |
inhibit the monoamine type B again making more dopamine more available. |
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what are dopaminergic drugs used for |
they are used highly in restless leg syndrome (nocturnal clamorous), in Parkinson- like symptoms, Parkinson disease and viral infections. |
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adverse reactions of a dopaminergic drug |
Carbidopa/Levedopa is most effective drug to used to relieve symptoms but after 3 to 5 years, the drugs effects gradually wears off and the patients suffered from on-off fluctuations in levedopa activity. |
