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84 Cards in this Set

  • Front
  • Back

What are the 3 types of muscle

1. Skeletal


2. Smooth


3. Cardiac

Where is smooth muscle mainly found?

Inside the walls your hollow organs and tubes (i.e. stomach and intestines)

Whats the difference between a tendon and a ligament?

Tendon: Muscle to bone


Ligament: Bone to bone

Define synergistically?

Multiple muscles working together to accomplish action

Whats the origin of a muscle? (define)

Usually more proximal; Immovable parts

Whats the insertion of a muscle? (define)

Usually more distal, causing the action

What are the two actions of a muscle? (define)

Agonist: Contracting to cause action




Antagonist: Relaxing to allow action

What are the 4 types of the muscle properties?

1. contract or to shorten


2. Stretch or to still generate force


3. recoil


4. Electrically excitable

Type of muscle: Skeletal (define)

- striated


- voluntary


- motor movement


- locomotion


- facial expression



Type of muscle: Smooth (define)

- Involuntary


- (i.e. Endocrine system)


- Autonomic nervous system

Type of muscle: Cardiac (define)

- Only found in the heart


- Cross between smooth and skeletal


- Involuntary


- Autonomic Nervous system



What is the description of a muscle cell

- Cyndrical (large or small in diameter)


- Large


- Multinucleated (located on perimeter)

Define muscle

Made up of bundles (Fasiciuli) of muscle cells/fibers

Whats an endomyseium?

Individual muscle fibers



Whats perimyseium?

Covers the fasiciuli

Whats epimyseium?

Covers the muscle, ends of muscle thickens and becomes tendon



Whats the difference between myo- and sarc-

Myo- Muscles relating to muscles




Sarc- Fleshy

Sacrolemma in muscles is similar to what in a cell?

Plasma membrane



Sacroplasmic Reticulum in muscles is similar to what in a cell?

Smooth ER

Sacroplasm in muscles is similar to what in a cell?

Cytoplasm

Whats the difference between thin and thick myofilaments?

Thin: Is full of actin (g/f-actin)




Thick: Full of myosin and ATP-ase (splits ATP apart)

Whats the 3 parts to trophomyosin?

1. Actin attachment


2. Tropomyosin attachment


3. Binds calcium

Whats a sacromere?

Basic repeating unit of a muscle

What are Z-disks made out of?

Boundaries of sacromeres

Whats the sliding filament theory?

Myofilaments that make up a sarcomere slide each other and shorten the sarcomere

Whats the milivolts (mV) of skeletal muscle in its resting membrane potential?

-85mV

What contributes to resting membrane potential?

The potassium (and sodium) gradients. Transports 2 potassium ions inside and 3 sodium ions outside at the cost of 1 ATP molecule.

Whats the activation process and how does it work?

- also known as "activation potential"




1. starts with cell at rest (-85mV) with stimulation


2. Ligand gated Na+ channel


3. Sodium enters inside cell


4. Charges go inside cell and goes positive


5. Then, voltage gated Na channel opens


6. Send the inside of a cell positive (depolarized)


7. voltage gated Na channels close and ligand


8. Voltage gated K+ channels open


9. Na+/K+ pump cleans up and reestablishes gradient

How does signal strength work?

It is accomplished by a p-frequency

Whats a synapse?

Transfer of info from nerve to the target

What's a neurotransmitter?

A chemical made in axon terminal released into synaptic cleft

What does ligand gated channels open?

Na+ channels and enters the cell and becomes positive

What happens with rigamortis?

Lack of ATP

What happens when Ca is released from sarcomere and binds to troponin?



The tropomyosin out of the way so myosin can bind

What happens when ATP use in muscle contraction?

1. Power contraction


2. Recovery


3. Lack of ATP causes cross bridges to keep hold


4. Na/K pumps and Ca pumps

Why are the movements fluid?

-b/c multiple nerves firing all at once, but slightly offset and are made of fast/slow twitch fibers

What are motor neurons?

Specialized nerve cells that stimulate muscles to contract

What are T-tubules (transverse tubules)?

Run along the surface of the sarcolemma are many tubelike invaginations of the sacrolemma

What is the cross bridge cycling?

To which heads of the myosin molecules are attached to slide over the surface of the myosin head releases from the actin and returns to its original position.





Whats a power strokes?

Movement of the myosin molecule while the cross bridge is attached

Whats the recovery stroke?

Return of the myosin head to its original position after cross bridge released

How does muscle relaxation work?

1. Its a passive process


2. decrease in Ca in sarcoplasm and acetylchonine in synaptic cleft


3. Once splits, acet. acetic diffuses and choline gets sucked into nerve and paired with another acet.


4. Muscle length dictates how well it contracts and force generated

Whats a muscle twitch?

One contraction/relaxation cycle from one single muscle fiber (no work is done)

What is the myasthenia gravis?

Nerves attack receptors; form of paralysis (auto-immune)

What are the two ways to control muscle work?

1. Summation




2. Recruitment

Whats the difference between summation and recruitment?

Summ: Changes the internal enviorment of the cell




Rec: (Motor units) increase the # of muscle fibers contracting increasing forces

Whats the differences in the motor unit sizes?

Big: One neuron controlling multiple fibers, large muscles movements




small: Few muscle fibers innervated by a single neuron (fine motor control)

Whats a treppe?

An increase in muscle tension with time and the same number of stimulus

Whats happens in a treppe?

1. With each stimulation, Ca is released




2. Increasing overall concentration of Ca in sarcoplasm

What are the 4 types of stimulus?

1. Subthreshold stimulus


2. Threshold Stimulus


3. Submaximal Stimuli


4. Maximal stimulus

What are the types of tetnus?

1. incomplete


2. complete

Whats the difference between incomplete and complete tetnus?

Incomplete: Muscles start to relax




Complete: No relaxation, always tense

What happens with tetnus?

- Increase motor units firing




- Lag time between sarcoma and contraction




- Increase in Ca in sacroplasm

What are the 4 types of muscle contraction?

1. Isometric


2. Isotonic


3. Concentric


4. Eccentric

Whats the difference between isometric and isotonic?

Isometric: Muscle generates force without changing length




Isotonic: Muscle generates force with a change in length

Whats the difference between concentric and eccentric?

Conc: Muscle shortens




Ecc: Muscle lengthens

Whats a muscle ton?

Motor units firing slightly off from each other so muscles that aren't being used have some tone.

How does muscle fatigue work?

1. Starts with a huge ATP demand, creatine will donate P to ADP to make ATP




2. Anaerobic respiration (O2 hate) and glucose converts to pyruvates and you make for ATP




3. Aerobic respiration (O2 love) finally makes up 36 ATP and gluclose

Whats hypertrophy?

Individual muscle grows due to training

How does recovery work AFTER exercise?

The body owes O2 and reforms/reestablishes creatine and phosphate stores

What are the two types of muscle fibers?

Slow twitch and fast twitch fibers

Whats the differences between the muscle fibers?

Slow: ATPase speeds up, cross bridge cycling speeds up and increase demand for ATP, mitochondria, blood supply and myoglobin




Fast: ATPase slows down, making cross bridge cycling slow down, decreasing demand for ATP

Which muscle fiber is better for aerobic respiration and has smaller diameter fibers?

Slow twitch fibers

Which muscle fiber is known for having short burst activity?

Fast twitch fibers

Whats atrophy?

Muscles decreasing in diameter due to lack of use

What are the 4 common effects of aging skeletal muscle?

1. Atrophy


2. Increase in synaptic cleft distance


3. Decrease in motor units


4. Loss of fine motor control

What are the 2 type of smooth muscle?

1. Viseral


2. Mulitunit

Whats an autorhythmic qualities?

Doesn't need neutral input

What are the common ways of smooth muscle?

1. Contract in response to stretch


2. Maintain tension with increased length


3. Most abundant


4. Actin/myosin is scattered and attached dense body





Whats a caveolae?

Shallow indents in sarcolemma

What happens during the steps of contraction of smooth muscle?

1. Signal travels along the sarcoma into caveoloe


2. Voltage gated Ca channel opens and Ca enters cell


3. Find the SR and signals release of more Ca


4. Ca binds to calmodulin, and once activated it turns on myosin kinase (attaches to phosphate to myosin heads)

What does a myosin phosphate do?

Removes the phosphate



Whats the differences between visceral and multiunit?

Visceral: Sheets of gap junction that acts in unison mainly




Multiunit: Act out of sync from each other

What are the characteristics of cardiac muscle?

- intercollated disks


- One nucleus


- Actin/Myosin

Describe the action potential of smooth muscle

1. Its resting membrane is -55milivolts


2. Has types of leak/open/close channels made of Na/Ca


3. Neurontransmitters can open or close channels


4. Nerves and hormones can make a membrane more sensitive or less sensitive

Whats the strongest muscle in the body?
Tounge
What does acectylcholine break into in muscles?
Acetic acid and chloine

What gives people the couch potato reflex?
The lack of acectlycholine
What are the 4 types of skeletal muscle fibers?

1. Type 1


2. Type 2a


3. Type 2b


4. Type x

Whats Type 1 muscle fibers?
Contract slow, high resistance to fatigue, low power, uses triglycerides for fuel and consumes lactic acid
What happens with type 2a muscle fibers?
Contract moderately fast, high resistance to fatigue, medium power, produces lactic acid and creatine phosphate
What happens with type 2b muscle fibers?
Contract fast, moderate resistance to fatigue, high power, consumes creatine phosphate, uses ATP, glycogen
What happens with type x muscle fibers?
Contract very fast, low resistance to fatigue, consume creatine phosphate
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