Chapter 6- Muscle Physiology 2

Front 1

Common features in all 3 muscles (4)

Back 1

1. composed of thick and thin filaments

2. contratile filaments respond to an increase in cystolic Ca

3. all muscles use ATP during CB activity

4. presence of SR which serve storage for Ca

Front 2

Smooth muscle

1. found in

2. striations?

3. shape

4. cells arrangement

5. structure

Back 2

1. walls of hollow organs and tubes

2. no striations

3. spindle-shaped cells with single nucleus

4. cells arranged in sheets within muscle

5. filaments don't for myofibrils, not arranged in sarcomere pattern, have dense bodies

Front 3

Smooth muscle cells have 3 types of filaments

Back 3

1. thick myosin filaments: longer than in skeletal muscle

2. thin actin filaments: contain tropomyosin but lack troponin

3. Intermediate size: not directly participate in contraction - part of cytoskeletal framework that supports cell shape

Front 4

Multi-unit smooth muscle

1. consists of

2. units must be stimulated in what way

3. found in

Back 4

(neurogenic)

1. discrete units that function independently of one another

2. units must be separately stimulates by nerves to contract

3. walls of large blood vess., large airways to lungs, ciliary body, iris, base of hair follicles

Front 5

Single unit smooth muscle

1. stimulated in what way?

2. also called

3. fibers becomes excited and contract as

4. cells electrically linked by

5. contraction is

6. can also be described as

Back 5

1. self-excitable (doesn't require nervous stimulation for contraction)

2. visceral smooth muscle

3. as single unit

4. linked by gap junctions

5. contraction is slow and energy efficient

6. can be described as a functoin syncytium

Front 6

Cardiac muscle

1. found in

2. striated?

3, cells interconnected by

4. fibers are joined in

4. innervated by

Back 6

1. walls of heart

2. striated

3. gap junctions

4. branching network

5. ANS

Front 7

Contraction in smooth muscl

Back 7

1. muscle excitation

2. increase in cystolic Ca (mostly from ECF)

3. series of biochemical events

4. phosphorylation of myosin cross bridges in thick filaments

5. binding of actin and myosin at cb

6. contraction

Front 8

Contraction in skeletal muscle

Back 8

1. excitation

2. increase in cystolic Ca (mostly from ICF)

3. physical repositioning of troponin and tropomyosin

4. uncovering of cb binding sites of actin

5. binding of actin and myosin at cb briges

6. contraction