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30 Cards in this Set

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Plasma Membrane

Known as the "gatekeeper"

Biological Membranes

Are phospholipid bilayers


Are semipermeable


Hydrophilic heads align toward water


Hydrophobic heads align away from water



Proteins are embedded here


Integral - tightly bound


Peripheral - on surface

Functions of membrane proteins

1. Ion Channels - ions pass


2. Transporter - larger molecules (glucose)


3. Receptors - hormone binding (specifically protein hormones), protein hormones never enter the cell.


4. Enzymes - embedded in membranes


5. Cell Identity Markers - tells wether something belongs or not. On the surface. Only cell that doesn't have identity markers are RBC's.


6. Linkers - anchor cells and internal structures (intercalated discs).

Two types of transport for materials across plasma membrane?

Passive and Active

Passive Processes

Simple Diffusion


Channel mediated diffusion


Facilitated diffusion


Osmosis

Simple Diffusion



A. What is simple diffusion?



B. What effects the rate of diffusion?



C. What DOES diffuse into cells?

A. Movement from higher concentration to lower concentration.



B. What effects the rate of diffusion?


Temperature, size (mass) of diffusing substance (gasses better than liquids), density, distance to travel (in lung .5), concentration difference.



C. What DOES diffuse into cells?


Oxygen, anything lipid, alcahol

Channel Mediated Diffusion

Ions and water

Facilitated Diffusion

Movement by transporter proteins.



Very specific (ex. Glucose)



Become more active when insulin binds.

Osmosis

Diffusion of water across a semi-permeable membrane.



Isotonic, hypotonic, hypertonic

Isotonic

The concentration is the same both inside and outside the cell. RBC's = 99.1%



The saline solution for IV's = 99.1% H2O and .9% NaCl

Hypotonic

Solute concentration of outside the cell is LOW. (Swells and burst)



Ex: if saline is .7% it would cause RBC's to swell and burst. Patient dead 😱.

Hypertonic

Solute concentration outside the cell is HIGH. (Shrivels)



Ex: if you give a patient saline too high in NaCl the RBC's will "sweat" and shrivel.

Active processes

Cost the cell energy (ATP)


Think of ATP like cash.


Primary, secondary, vesicles

Primary Active Transport

Uses transporters and energy to move low ➡️ high concentration.



(Concentrating uses active transport)

Secondary Transport

Energy stored in a concentration gradient used to move other substances

Vesicles

Endocytosis and Exocytosis

Vesicles

Endocytosis and Exocytosis

Endocytosis

Movement of large particles into cell by vesicles formation. (WBC's)



Phagocytosis


Pinocytosis

Phagocytosis

Eating something solid (cell feeding)

Pinocytosis

Cell drinking

Exocytosis

Movement of large particles out of the cell. Vesicles fuse with plasma membrane.

Cell Division

Cell cycle


Stages of mitosis

Cell Division

Cell cycle


Stages of mitosis

Interphase

Most cells are in this phase.


(G1, *S, G2) G = growth


S = copying DNA


If a cell moves from G1 to S it's decided to divide.

Mitosis

PMAT

Prophase

(Ball of dark lines with no membrane)



Nuclear membrane & a nucleolus disintegrate.



Chromatin fibers coil tightly to become chromosomes.



Centrosomes begin to produce spindle fibers.

Metaphase

(Dark line attached to spindle fiber)



Chromosomes attached to spindle fibers are aligned on the middle of the cell.

Anaphase

(Dark line pulled apart) spindle fibers pull sister chromatids apart at their centromere.

Telophase

(Boobs)


The identical sets of chromosomes now at the opposite poles begin to uncoil to become chromatin.



Nuclear membranes & nuclei reform.



Look for cleavage furrow.



*Cytokenesis Occurs

Cytokenesis

Division of the cytoplasm by cleavage furrow formation.