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11 Cards in this Set
- Front
- Back
- 3rd side (hint)
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what is the lipoprotein is taken up by macrophages, which then invade the coronary endothelium to initiate plaque formation
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oxidized low density lipoprotein (LDL)
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what is the characteristic lactate dehydrogenase isoenzyme pattern in acute myocardial infarction?
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LD1>LD2
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what relative index (RI) of creatine kinase MB antigen mass (CK-MB) to total CK activity suggest AMI?
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2%
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most important laboratory test for acute coronary syndrome (ACS)?
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cardiac troponin (cTn); both cTnI and cTnT are in use
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reasons for the high specificity of cardiac troponin I and T (cTnI, cTnT)?
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assays are specific for the cardiac forms
both cTnI and cTnT are essentially absent from the normal serum |
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how long after an AMI does cTn peak?
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24hours
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63 yom AMI, 12 hours later cTnI levels begin to gradually rise again. The patient denies chest pain. Does this represent a second, silent AMI?
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no; the majority of cTn is bound to muscle fibers and is released more slowly in the week-plus after the AMI
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what is the window of opportunity for using myoglobin as a marker for cardiac injury?
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elevated serum levels are apparent within 2-3 hours after AMI, return to baseline by 24hours
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hs-CRP is the current analyte of choice as an inflammatory marker for risk assessment of CHD , universal screening is not recommended
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hs-CRP is the current analyte of choice as an inflammatory marker for risk assessment of CHD , universal screening is not recommended
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when is a homocysteine measurement warranted?
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if a person who is at low risk of CHD, based on traditional risk factors develops CHD; then a homocysteine level may provide some other useful data
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BNP limitations as an analyze for HF?
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BNP is not especially specific marker as it is elevated in other conditions of fluid imbalance such as renal failure; chronic HF patients with stable disease may have values within the reference range; intra-individual variation can be as great as 30-40% in chronic HF patients with stable disease
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