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58 Cards in this Set
- Front
- Back
Skeletal cartilage
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avascular tissue
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All skeletal cartilage contains
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chondrocytes in laminate and extracellular matrix
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Hyaline Cartilage
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provides support flexibilIty, resilience. collagen fibers only; most abundant type
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Elastic cartilage
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similar to hyaline cartilage but contains elastic fibers.
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Fibrocartilage
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Thick collagen fibers has great tensile strength.
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Appositional growth
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Cells secrete matrix against external face of existing cartilage.
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Interstitial growth
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Chondrocytes divide and secrete new matrix. Expanding cartilage from within.
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Axial skeleton
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Long axis of body skull vertebral column rib cage
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Appendicular skeleton
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Bones of upper and lower limbs girdles attaching limbs to axial skeleton
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Function of Bones
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Support, protection , movement
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Hematopoiesis
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Blood cell formation in marrow cavities of certain bones.
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Osteocalcin
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Hormone production. Regulate bone formation and protects against obesity glucose intolerance diabetes mellitus
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Bones (organ) tissues
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Osseous tissue nervous tissue cartilage fibrous connective tissue muscle and epithelial cells and its blood vessels
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Three levels of structure
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Gross anatomy microscopic chemical
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Compact
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Dense outer layer smooth and solid
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Spongy (cancellous or trabecular)
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Honeycomb of flat pieces of bones deep to compact called trabeculae
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Periosteum
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Two distinct regions (fibrous and osteogenic) grow on the outside of the bone muscle and tendon attachment to this area.
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Sharpeys Fibers
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anchors the periosteum to bone.
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spongy bone houses
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Red bone marrow
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Articular cartilage a.k.a.
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Hyaline Cartilage.
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Diaphysis
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Tubular shaft forms long axis compact bone surrounding medullary cavity
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Epiphyses
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Bone ends external compact ,internal spongy bone ,articular cartilage covers articular surfaces Between is epiphysial line.
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Medullary cavity lined by
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endosteum
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Endostium
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delicate connective tissue membrane covering internal bone surface covers trabeculae of spongy bone. lines canals that pass through compact bone (medullary cavity) contains osteogenic cells
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Osteogenic cells
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differentiate into other cells.
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Red marrow
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found within trabecular cavities of spongy bone and diploe of flat bones.
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osteoblast
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form bone
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osteocytes
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maintain bone
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osteoclast
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breakdown bone
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compact bone aka
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lamellar bone
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osteon or haversian system
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structural unit of compact bone.
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lamellae
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hollow tubes of bone matrix
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central (haversian) system runs through
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core of osteon. contains blood vessels and nerve fibers.
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perforating (volkmann's) canals
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canals lined with endosteum at right angles to central canal. Connect blood vessels and nerves of periosteum, medullary cavity, and central canal.
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lacunae
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small cavities that contain onsteocytes
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canaliculi
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hair like canals that connect lacunae to each other and central canal.
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osteoid
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1/3 of organic bone matrix secreted by osteoblasts. (proteoglycans and glycoprotein) collagen Fibers strength.
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Hydroxyapatites (mineral salts)
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65% of bone mass. made of calcium salts. responsible for hardness.
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ossification (osteogenesis)
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process of bone tissue formation
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endochondral ossification
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bone forms by replacing hyaline cartilage. forms most of skeleton
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intramembraneous ossification
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Bone develops from fibrous tissue connective tissue. bones called membrane bones. (flat, clavicle, and cranial)
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parathyroid hormone (pth)
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produced by parathyroid glands. Removes calcium from bone regardless of bone integrity
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calcitonin
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produced by parafollicular cells ofb thyroid. in high doses lowers blood calcium levels temporarily.
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Hyperexcitability
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calcium levels too low
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Nonresponsiveness
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calcium levels too high
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Leptin
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Hormone released by adipose tissue. Role in bone density regulation. Inhibits osteoblast in animals
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Seratonin
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Neurotransmitter regulating mood and sleep. Most made in gut. Secreted into blood after eating. interfers with osteoblast activity.
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Nondisplaced fracture
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end retains normal position
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Displaced
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End is out of normal alignment
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complete
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Broken all the way through
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incomplete
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Not broken all the way through
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open
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Skin is penetrated
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closed
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skin is not penetrated
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Osteomalacia (adults)
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Bones poorly mineralized. calcium salts not adequate. soft weak bones. pain upon bearing weight. lack of vitamin d
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Rickets (osteomalacia of children)
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Bowed legs and other bone deformities. Bones ends enlarged an abnormally long. Vitamin d deficiency or dietary calcium.
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Osteoporosis
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Bone resorption outpaces deposits. Spongy bone of spine and neck of femur most susceptible. Vertebral and hip fractures common
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pagets disease
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Excessive and haphazard bone deposit and resorption. bone made fast but poorly. Treatments are calcitonin increase quality biphosphonates.
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Treating osteoporosis
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calcium vitamin d weight bearing exercises hormone replacement therapy
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