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58 Cards in this Set

  • Front
  • Back
Skeletal cartilage
avascular tissue
All skeletal cartilage contains
chondrocytes in laminate and extracellular matrix
Hyaline Cartilage
provides support flexibilIty, resilience. collagen fibers only; most abundant type
Elastic cartilage
similar to hyaline cartilage but contains elastic fibers.
Fibrocartilage
Thick collagen fibers has great tensile strength.
Appositional growth
Cells secrete matrix against external face of existing cartilage.
Interstitial growth
Chondrocytes divide and secrete new matrix. Expanding cartilage from within.
Axial skeleton
Long axis of body skull vertebral column rib cage
Appendicular skeleton
Bones of upper and lower limbs girdles attaching limbs to axial skeleton
Function of Bones
Support, protection , movement
Hematopoiesis
Blood cell formation in marrow cavities of certain bones.
Osteocalcin
Hormone production. Regulate bone formation and protects against obesity glucose intolerance diabetes mellitus
Bones (organ) tissues
Osseous tissue nervous tissue cartilage fibrous connective tissue muscle and epithelial cells and its blood vessels
Three levels of structure
Gross anatomy microscopic chemical
Compact
Dense outer layer smooth and solid
Spongy (cancellous or trabecular)
Honeycomb of flat pieces of bones deep to compact called trabeculae
Periosteum
Two distinct regions (fibrous and osteogenic) grow on the outside of the bone muscle and tendon attachment to this area.
Sharpeys Fibers
anchors the periosteum to bone.
spongy bone houses
Red bone marrow
Articular cartilage a.k.a.
Hyaline Cartilage.
Diaphysis
Tubular shaft forms long axis compact bone surrounding medullary cavity
Epiphyses
Bone ends external compact ,internal spongy bone ,articular cartilage covers articular surfaces Between is epiphysial line.
Medullary cavity lined by
endosteum
Endostium
delicate connective tissue membrane covering internal bone surface covers trabeculae of spongy bone. lines canals that pass through compact bone (medullary cavity) contains osteogenic cells
Osteogenic cells
differentiate into other cells.
Red marrow
found within trabecular cavities of spongy bone and diploe of flat bones.
osteoblast
form bone
osteocytes
maintain bone
osteoclast
breakdown bone
compact bone aka
lamellar bone
osteon or haversian system
structural unit of compact bone.
lamellae
hollow tubes of bone matrix
central (haversian) system runs through
core of osteon. contains blood vessels and nerve fibers.
perforating (volkmann's) canals
canals lined with endosteum at right angles to central canal. Connect blood vessels and nerves of periosteum, medullary cavity, and central canal.
lacunae
small cavities that contain onsteocytes
canaliculi
hair like canals that connect lacunae to each other and central canal.
osteoid
1/3 of organic bone matrix secreted by osteoblasts. (proteoglycans and glycoprotein) collagen Fibers strength.
Hydroxyapatites (mineral salts)
65% of bone mass. made of calcium salts. responsible for hardness.
ossification (osteogenesis)
process of bone tissue formation
endochondral ossification
bone forms by replacing hyaline cartilage. forms most of skeleton
intramembraneous ossification
Bone develops from fibrous tissue connective tissue. bones called membrane bones. (flat, clavicle, and cranial)
parathyroid hormone (pth)
produced by parathyroid glands. Removes calcium from bone regardless of bone integrity
calcitonin
produced by parafollicular cells ofb thyroid. in high doses lowers blood calcium levels temporarily.
Hyperexcitability
calcium levels too low
Nonresponsiveness
calcium levels too high
Leptin
Hormone released by adipose tissue. Role in bone density regulation. Inhibits osteoblast in animals
Seratonin
Neurotransmitter regulating mood and sleep. Most made in gut. Secreted into blood after eating. interfers with osteoblast activity.
Nondisplaced fracture
end retains normal position
Displaced
End is out of normal alignment
complete
Broken all the way through
incomplete
Not broken all the way through
open
Skin is penetrated
closed
skin is not penetrated
Osteomalacia (adults)
Bones poorly mineralized. calcium salts not adequate. soft weak bones. pain upon bearing weight. lack of vitamin d
Rickets (osteomalacia of children)
Bowed legs and other bone deformities. Bones ends enlarged an abnormally long. Vitamin d deficiency or dietary calcium.
Osteoporosis
Bone resorption outpaces deposits. Spongy bone of spine and neck of femur most susceptible. Vertebral and hip fractures common
pagets disease
Excessive and haphazard bone deposit and resorption. bone made fast but poorly. Treatments are calcitonin increase quality biphosphonates.
Treating osteoporosis
calcium vitamin d weight bearing exercises hormone replacement therapy