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46 Cards in this Set
- Front
- Back
Location and function of Lacteals |
-Found in the Small Intestine -Lymphatic capillaries that absorb fats as they enter and pass through the vessels |
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Location of Peyer's Patches |
The walls of the Small Intestine |
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Two major tissues in the spleen |
White pulp and red pulp |
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White Pulp of the Spleen |
-Contain B Cell and T Cell Lymphocytes |
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Red Pulp of the Spleen |
Worn out RBC and Macrophages |
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Two major tissues found within the Thymus |
-Epithelial Cells
???? |
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Where do B-Cells mature? |
Bone marrow |
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Where do T-Cells mature? |
Thymus |
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What are the two types of immunity? |
Innate: born with, nonspecific Adaptive: specific |
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What is the function of interferons? |
Proteins Trigger for help Interferes with virus replication Stimulate NK Cells and Macrophages |
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List the cells involved in Innate immunity |
Neutrophil Monocyte *Macrophages *Dendritic *NK Mast Cell Basophils Eosinophils |
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What is an autoimmune disease? |
Adaptive immunity treats self-antigens as foreign antibodies; attack itself |
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Function of NK Cells |
-"Police" -Monitor tissues looking for abnormal cells Nonselective and contact killing |
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What are clones? |
Identical lymphocytes |
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What is an antigenic determinant? |
Specific regions of a given antigen recognized by a lymphocyte
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The types of T-Cells |
Cytotoxic, Suppressor, Helper |
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Cytotoxic T-Cell |
"Action Movie" Perforin destroys, blows up Slow Response |
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Suppressor T-Cell |
"The Brakes"
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Helper T-Cell |
"The General" Activate and organize CD4 T-Cells Most Important |
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What is a MHC? |
Markers that say you are you
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Two types of MHC- |
Class I and Class II |
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List the CD4 Cells |
Helper T-Cells- Class II |
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List the CD8 cells |
T-Suppressor and Cytotoxic-T; Class I |
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Function of the plasma cells |
Make antibodies |
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Function of a B Cell |
Differentiate into plasma cells upon stimulation |
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Describe the antibody structure |
Proteins produced in response to antigen; Y shaped; 2 heavy chains and 2 light chains |
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What is an immunoglobulin? |
Antibodies- globulin proteins involved in immunity (5 of them)
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Function of the memory B Cell |
Long-lasting immunity |
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Active Immunity |
Antibodies that result in response to antigens- natural acquired and active artificial |
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Passive Immunty |
Transfer of antibodies from one person to another- passive natural and passive artificial |
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Naturally Activated Immunity |
Come across naturally |
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Active Artificial Immunity |
Vaccine/flu shot |
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Passive Nature Immunity |
Breastmilk/placenta |
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Passive Artificial Immunity |
Snake Bites; antivenum |
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IgG |
Largest, most diverse Virus, bacteria and toxins Can gross placenta |
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IgE |
Attaches to basophils and mast cells Helpful in allergic reactions |
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IgD |
Surface of B Cells Binds to antigens in extracellular fluid Role in activation |
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IgM |
First secreted into body Not very effective in fighting, but helps High concentration until igG increases |
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IgA |
Glandular secretions- mucus, tears, saliva Attack pathogens before they gain access to internal tissues |
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The flow of lymph through the Lymphocytes |
(in) Afferent lymphocytes Subcapular Sinus Outer Cortex Deep Cortex Medullar Efferent lymphocytes (out) |
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Know the Lymphatic Organs and locations |
Peyer's patches Tonsils Lymph Nodes Thymus Spleen
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Be able to differentiate between he thoracic duct and right lymphatic duct in terms of drainage |
Lymphatic duct: connect to subclavian vein; right arm and right half of head
Thoracic Duct: left part of head and rest of the body |
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Functions of the Spleen |
Limited revoir for blood |
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What are pyrogens? What does symptom do the release of them cause to body? |
Released when the body in invaded (virus); brings up the body temperature |
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Explain how innate, antibody mediated and cell mediated immunity function together- |
- |
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Types of Innate Immunity |
Physical Barriers Phagocytes NK Cells Interferons Complement System Inflammation Fever |