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46 Cards in this Set

  • Front
  • Back

Location and function of Lacteals

-Found in the Small Intestine


-Lymphatic capillaries that absorb fats as they enter and pass through the vessels

Location of Peyer's Patches

The walls of the Small Intestine

Two major tissues in the spleen

White pulp and red pulp

White Pulp of the Spleen

-Contain B Cell and T Cell Lymphocytes

Red Pulp of the Spleen

Worn out RBC and Macrophages

Two major tissues found within the Thymus

-Epithelial Cells



????

Where do B-Cells mature?

Bone marrow

Where do T-Cells mature?

Thymus

What are the two types of immunity?

Innate: born with, nonspecific


Adaptive: specific

What is the function of interferons?

Proteins


Trigger for help


Interferes with virus replication


Stimulate NK Cells and Macrophages

List the cells involved in Innate immunity

Neutrophil


Monocyte


*Macrophages


*Dendritic


*NK


Mast Cell


Basophils


Eosinophils

What is an autoimmune disease?

Adaptive immunity treats self-antigens as foreign antibodies; attack itself

Function of NK Cells

-"Police"


-Monitor tissues looking for abnormal cells


Nonselective and contact killing

What are clones?

Identical lymphocytes

What is an antigenic determinant?

Specific regions of a given antigen recognized by a lymphocyte


The types of T-Cells

Cytotoxic, Suppressor, Helper

Cytotoxic T-Cell

"Action Movie"


Perforin destroys, blows up


Slow Response

Suppressor T-Cell

"The Brakes"


Helper T-Cell

"The General"


Activate and organize


CD4 T-Cells


Most Important

What is a MHC?

Markers that say you are you


Two types of MHC-

Class I and Class II

List the CD4 Cells

Helper T-Cells- Class II

List the CD8 cells

T-Suppressor and Cytotoxic-T;


Class I

Function of the plasma cells

Make antibodies

Function of a B Cell

Differentiate into plasma cells upon stimulation

Describe the antibody structure

Proteins produced in response to antigen; Y shaped; 2 heavy chains and 2 light chains

What is an immunoglobulin?

Antibodies- globulin proteins involved in immunity (5 of them)


Function of the memory B Cell

Long-lasting immunity

Active Immunity

Antibodies that result in response to antigens- natural acquired and active artificial

Passive Immunty

Transfer of antibodies from one person to another- passive natural and passive artificial

Naturally Activated Immunity

Come across naturally

Active Artificial Immunity

Vaccine/flu shot

Passive Nature Immunity

Breastmilk/placenta

Passive Artificial Immunity

Snake Bites; antivenum

IgG

Largest, most diverse


Virus, bacteria and toxins


Can gross placenta

IgE

Attaches to basophils and mast cells


Helpful in allergic reactions

IgD

Surface of B Cells


Binds to antigens in extracellular fluid


Role in activation

IgM

First secreted into body


Not very effective in fighting, but helps


High concentration until igG increases

IgA

Glandular secretions- mucus, tears, saliva


Attack pathogens before they gain access to internal tissues

The flow of lymph through the Lymphocytes

(in) Afferent lymphocytes


Subcapular Sinus


Outer Cortex


Deep Cortex


Medullar


Efferent lymphocytes (out)

Know the Lymphatic Organs and locations

Peyer's patches


Tonsils


Lymph Nodes


Thymus


Spleen


Be able to differentiate between he thoracic duct and right lymphatic duct in terms of drainage

Lymphatic duct: connect to subclavian vein; right arm and right half of head



Thoracic Duct: left part of head and rest of the body

Functions of the Spleen

Limited revoir for blood

What are pyrogens? What does symptom do the release of them cause to body?

Released when the body in invaded (virus); brings up the body temperature

Explain how innate, antibody mediated and cell mediated immunity function together-

-

Types of Innate Immunity

Physical Barriers


Phagocytes


NK Cells


Interferons


Complement System


Inflammation


Fever