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29 Cards in this Set

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  • Back
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What are the 3 stages of cell communication?
1. Reception
2. Transduction
3. Response
p.200
Which 2 types of signaling are local?
1. Paracrine signaling
2. Synaptic signaling
p.199
Which type of signaling signals over greater distances?
Hormonal
p.199
What type of signaling does PDGF use?
Paracrine
p.199
What type of signaling does Acetylcholine use?
Synaptic Signaling
p.199
What type of signaling does epinephrine use?
Hormonal
p.199
What type of signaling does testosterone use?
Hormonal
p.199
What is otherwise known as the fight or flight hormone?
Epinephrine
Class notes 3/22/04
What is known as the process by which a signal on a cell's surface is converted into a specific cellular response in a series of steps?
Signal Transduction Pathway
p.198
What type of receptor does epinephrine use?
G-Protein linked receptor
p.201
What type of receptor does testosterone use?
Intracellular receptor
p.204
What type of receptor does acetylcholine use?
Ion-Channel Receptor
p.204
What type of receptor does PDGF use?
Tyrosine-Kinase Receptor
p.203
Cell signaling is also known as ___?
Signal Transduction
What enzyme does G-Protein bind to?
Adenylyl Cyclase
p.202
What type of cellular response does epinephrine promote?
Increased heart rate
Increased blood pressure
Increased sweat
Muscle contraction
Notes 3/22
What is the first and second messengers in cell signaling from Epinephrine?
1st = Epinephrine itself
2nd = cAMP
A protein changes shape during which stage of cell signaling?
Transduction
Notes 3/22
Which receptors are located at the Plasma Membrane?
G-Protein Linked Receptor
Tyrosine-Kinase Receptor
Ion Channel Receptor
p.202-4
Which receptor is not located at the plasma membrane?
Intracellular Receptor
(Cytosolic Receptor Protein)
p.204
What moves into the nucleus and becomes a transcription factor?
Cytosolic receptor protein
p.204
What type of special protein controls which genes are turned on and are transcribed into mRNA?
Transcription Factors
p.204
What type of cellular response does testosterone promote?
Lower voice, facial hair
Notes 3/22
What type of cellular response does acetylcholine promote?
Increase strength and rate of muscle contraction
Notes 3/22
What is the signal molecule called that attaches to the gated ion channel?
Ligand
Notes 3/22
What type of cellular response does PDGF promote?
Mitosis (healing)
notes 3/22
What is a major mechanism of signal transduction?
Protein phosphorylation
p.213
What 2 activities does a cell regulate in response to a signal?
1. Regulate enzyme activity
2. Regulate genes
p.213
When does the amplification of a chemical signal occur?
When a receptor in the plasma membrane activates several G-protein molecules while a signal molecule is bound to it.
p.214