Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
10 Cards in this Set
- Front
- Back
|
Diffusion and dilution test that expose pathogens to antimicrobials are designed to __. D |
a. determine the spectrum of action of a drug b. determine which drug is most effective against a particular pathogen c. determine the amount of a drug to use against a particular pathogen d. both b and c |
|
|
In a Kirby-Bauer susceptibility test, the presence of a zone of inhibition around disks containing antimicrobial agents indicates___. A |
a. that the microbe does not grow in the presence of the agents. b. that the microbe grows well in the presence of the agents c. the smallest amount of the agent that will inhibit the growth of the microbe d. the minimum amount of an agent that kills the microbe in question |
|
|
The key to succussful chemotherapy is ____. a. selective toxicity b. a diffusion test c. the minimum inhibitory concentration test d. the spectrum of action |
A |
|
|
Which of the following statements is relevant in explaining why sulfonamides are effective: C |
a. Sulfonamides attach to sterol lipids in the pathogen, disrupt the membranes, and lyse the cells. b. Sulfonamides prevent the incorporatiion of amino acids into polypeptide chains. c. Humans and microbes use PABA differently in their metabolism. d. Sulfonamides inhibit DNA replication in both pathogens and human cells. |
|
|
Cross resistance is _____. D |
a. the deactivation of an antimicrobial agent by a bacterial enzyme. b. alteration of the resistant cells so that an antimicrobial agent cannot attach c. the mutation of genes that affect the cytoplasmic membrane channels so the antimicrobial agent cannot cross into the cell's interior d. resistance to one antimicrobial agent because of it similarity to another antimicrobial agent. |
|
|
Multiple-drug-resistant microbes______. a. are resistant to all antimicrobial agents b. respond to new antimicrobials by developing resistance c. frequently develop in hospitals d. all of the above |
C |
|
|
Which of the following is most closely associated with a beta-lactam ring? a. penicillin b. vancomycin c. bacitracin d. isoniazid |
A |
|
|
Drugs that act against protein synthesis include ___ a. beta-lactams b. trimethoprim c. polymyxin d. aminoglycosides |
D |
|
|
Which of the following statements is false concerning antiviral drugs? A |
a. Macrolide drugs block attachment sites on the host cell wall and prevent viruses form entering. b. Drugs that neutralize the acidity of phagolysosomes prevent viral uncoating. c. Nucleotide analogs can be used to stop microbial replication. d. Drugs containing protease inhibitors retard viral growth by blocking the production of essential viral proteins. |
|
|
PABA is _______. a. a substrate used in the production of penicillin b. a type of β-lactamase c. molecularly similar to cephalosporins d. used to synthesize folic acid |
D |
