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18 Cards in this Set
- Front
- Back
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Origin of Replication |
A particular sequence in a genome at which replication is initiated. |
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Replication Fork |
The leading strand of DNA is the strand being synthesized in the same direction as the growing replication fork. |
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What is helicase? |
The enzyme that is responsible for seperating double-stranded DNA into single strands allowing for replication |
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What is DNA primase? |
DNA primase is an enzyme that catalyzes the synthesis of a short RNA (or DNA in some organisms) segment called the primer complementary to ssDNA template |
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RNA Primer |
Serves as a starting point for DNA synthesis |
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DNA polymerase |
Enzymes that synthesize DNA molecules from deoxyribonucleotides |
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Leading Strand |
Continuously replicated in the 3' to 5' direction |
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Lagging Strand |
Discontinuously replicated in short sections |
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Okazaki Fragments |
Short, newly synthesized DNA fragments that are formed in the lagging strand during DNA replication. |
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DNA Ligase |
Enzyme that connects (ligates) the Okazaki fragments onto the (now continuous) newly synthesized complementary strand. |
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Mitosis |
A type of cell division that results in two daughter cells each having the same number and kind of chromosomes as the parent nucleus. |
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Sister Chromatids |
Either of the two identical copies (chromatids) formed by the replication of a single chromosome. 1/2 of the duplicated chromosome. |
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Centromere |
The region of a chromosome to which the microtubules of the spindle attach during cell division. |
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Cohesin |
Protein complex that regulates the separation of sister chromatids during cell division. |
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Seperase |
Cysteine protease responsible for triggering Anaphase by hydrolysing cohesion |
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Centrosomes |
An organelle near the nucleus that contains the centrioles from which the spindle fibers develop in cell division |
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Mitotic Spindle |
The Macromolecular machine that segregates the two daughter cells Major structural elements are the microtubule polymers |
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Kinetochore |
Complex of proteins associated with the centromere of the chromosome during cell division |
