Case 5 Micro Ch 10

Front 1

Antibodies have 3 heavy chain and 3 light chain _______ sites referred to as complementary determining regions.

Back 1

Hypervariable

These are the sites that are produced in bulk after exposure to antigens

Front 2

The common backbone that the 3 heavy chain and 3 light chains are bound to is known as the ___ region

Back 2

Fc

The Fc region serves as a common site for Ig recognition by host cells

Front 3

Name the two additional complement fragments in the classical pathway that must be activated BEFORE reaching C3 and becoming the same as the alternative pathway

Back 3

C4--->C2----->C3

Front 4

Ig_: Most abundant, usually a sign of immunity/past exposure. Crosses placenta

Back 4

IgG

Front 5

Ig_: Polymerized to a double unit (dimeric). Protects mucosal surfaces.

Back 5

IgA

Front 6

Ig_: Polymerized to a multimeric unit (pentameric). Major complement activator.

Back 6

IgM

Front 7

Ig_: Fights parasites and causes allergic reactions

Back 7

IgE

Front 8

Ig_: Mainly a lymphocyte receptor

Back 8

IgD

Front 9

Thelper__: helps macrophages kill intracellular infection

Back 9

1

Front 10

Thelper__: helps B cells make antibody

Back 10

2

Front 11

Three types of cells that work through antibody dependent cellular cytotoxicity to take out big parasites

Back 11

Macrophages
Eosinophils
NK cells