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116 Cards in this Set

  • Front
  • Back
Triamterene
Na+ channel blocker - prevent K+ loss
Amiloride
Na+ channel blocker - prevent K+ loss
Spironolactone
Aldosterone Receptor Antagonist - prevent K+ loss
Eplerenone
Aldosterone Receptor Antagonist - prevent K+ loss
Propranolol
Non-selective B antagonist
Nadolol
Non-selective B antagonist
Timolol
Non-selective B antagonist
Pindolol
Non-selective B antagonist
Carteolol
Non-selective B antagonist
Levobunolol
Non-selective B antagonist
Metoprolol
Selective B1 antagonist
Atenolol
Selective B1 antagonist
Acebutolol
Selective B1 antagonist
Betaxolol
Selective B1 antagonist
Bisoprolol
Selective B1 antagonist
Esmolol
Selective B1 antagonist
Nebivolol
Selective B1 antagonist at 10 mg or less; Non-selective at 10 mg or more - stimulates nitric oxide activity
Verapamil
Calcium Channel Blocker - Non-DHP
Diltiazem
Calcium Channel Blocker - Non-DHP
Nifedipine
Calcium Channel Blocker - DHP
Amlodipine
Calcium Channel Blocker - DHP
Isradipine
Calcium Channel Blocker - DHP
Felodipine
Calcium Channel Blocker - DHP
Nisoldipine
Calcium Channel Blocker - DHP
Nimodipine
Calcium Channel Blocker - DHP - Somewhat selective for cerebral arterioles - useful with subarachnoid hemorrhage
Nicardipine
Calcium Channel Blocker - DHP
Clevidipine
Calcium Channel Blocker - DHP
Calcium Channel Blockers that act on the vasculature
Dihydropyridines (DHP)
Calcium Channel Blockers that act on the heart
Verapamil and Diltiazem
Captopril
ACE Inhibitor
Enalapril
ACE Inhibitor
Lisinopril
ACE Inhibitor
Ramipril
ACE Inhibitor
Quinapril
ACE Inhibitor
Fosinopril
ACE Inhibitor
Benazepril
ACE Inhibitor
Moexipril
ACE Inhibitor
Perindopril
ACE Inhibitor
Trandolapril
ACE Inhibitor
Mechanism of action for ACE Inhibitors
Inhibits the production of Angiotensin II and inhibits the breakdown of bradykinin
Captopril
ACE Inhibitor
Adverse effects of Captopril
Loss of taste (metallic taste) and skin rash
Losartan
ARB antagonist
Valsartan
ARB antagonist
Candesartan
ARB antagonist
Irbesartan
ARB antagonist
Telmisartan
ARB antagonist
Eprosartan
ARB antagonist
Olmesartan
ARB antagonist
Aliskiren
Renin inhibitor
Hydrochlorothiazide
Thiazide Diuretics
Chlorthalidone
Thiazide Diuretics
Metolazone
Thiazide Diuretics
Chlorothiazide
Thiazide Diuretics
Bendroflumethiazide
Thiazide Diuretics
Methyclothiazide
Thiazide Diuretics
Polythiazide
Thiazide Diuretics
Trichlormethiazide
Thiazide Diuretics
Furosemide
Loop Diuretics
Torsemide
Loop Diuretics
Bumetanide
Loop Diuretics
Ethacrynic acid
Loop Diuretics
K+ sparing diuretics
Triamterene and Amiloride (Na Channel blockers); Spironolactone and Eplerenone (aldosterone antagonist)
Diuretics to use on patient with stable angina
B blocker and calcium channel blocker (think Non-DHP's to avoid reflex tachycardia)
Diuretics to use on patient with acute coronary syndrome (unstable angina or myocardial infarction)
B blocker or ACE inhibitor
Diuretics to use on patient with postmyocardial infarction
B blocker, ACE inhibitor, or Aldosterone antagonist
Diuretics to use on patient with GFR <60 ml/min per 1.73m2
ACE inhibitor or ARB
Diuretics to use on patient with GFR <30 ml/min per 1.73m2
Loop diuretics in combination with other drugs
Recurrent stroke rates are lowered with a combination of these diuretics
ACE inhibitor and Thiazide diuretic
First line diuretics for African American patient
Thiazide diuretic or Calcium Channel blocker
First line diuretics for pregnancy
Methyldopa, B-blockers, vasodilators
Don’t use these hypertension drugs in pregnant or sexually active girls
ARBs or ACE inhibitors (teratogenic)
Hypertension drug to use with patient with hypertension and osteoporosis
Thiazide diuretics
Hypertension drug to use with patient with hypertension and atrial tachyarrhythmias/fibrillation, migraines, thyrotoxicosis, essential tremor
B-blockers
Hypertension drug to use with patient with hypertension and Raynaud's syndrome and certain arrhythmias
Calcium Channel blockers
Hypertension drug to use with patient with hypertension and prostatism
Alpha blockers
Hypertension drugs not to use with patients with hypertension and gout or hyponatremia
Thiazide diuretics
Hypertension drugs not to use with patients with hypertension and asthma or 2nd or 3rd degree heart block
B-blockers
Hypertension drugs not to use with patients with hypertension and likely to be pregnant
ACE inhibitors or ARBs
Hypertension drugs not to use with patients with hypertension and history of angioedema
ACE inhibitors
Hypertension drugs not to use with patients with hypertension and hyperkalemia
Potassium sparing diuretics (aldosterone antagonists and Na Channel blockers) and ACE inhibitors
Diabetic Patient comes in with hypertension - first line drug?
ACE inhibitors or ARBs because of their protective kidney benefits
Phentolamine
Non-selective a-blocker - not used to treat essential hypertension
Phenoxybenzamine
Non-selective a- - not used to treat essential hypertension
Prazosin
Selective a1 blocker
Terazosin
Selective a1 blocker
Doxazosin
Selective a1 blocker
Labetalol
a and b-blocker
Methyldopa
Centrally acting a2 agonist - used for hypertension with pregnancy
Clonidine
Centrally acting a2 agonist - transdermal patch is better tolerated
Adverse effects of methyldopa
Positive Coombs test (common) - hemolytic anemia (rare) - hepatotoxicity
Adverse effects of clonidine
Rebound hypertension (can be very severe) - nervousness, tachycardia, headache and sweating
Artery vasodilators
Hydralazine, Minoxidil, and Fenoldopam
Artery and vein vasodilator
Nitroprusside
Mechanism of action for minoxidil
Activates K+ channels on arterial smooth muscle thus hyperpolarizing them
Adverse effects for Hydralazine
Lupus-like syndrome - fever, arthralgia, skin rashes
Adverse effect for Minoxidil
Hypertrichosis
Mechanism of action for Fenoldopam
Activates dopamine D1 receptors
Mechanism of action for Nitroprusside
Increased Nitric Oxide - increases cGMP - arterial and venous vasodilation
Adverse effects of cyanide and thiocyanate toxicity
Nitroprusside
Hypertension drug that works the fastest for an Urgency/Emergency
Nitroprusside
Most frequent signs of a hypertension urgency
headache, epistaxis, faintness/agitation
Most frequent signs of a hypertension emergency
chest pain, dyspnea, and neurological deficit
Drugs to use for hypertensive encephalopathy, central nervous system event, or renal failure
Labetalol, Nitroprusside, and Fenoldopan
Drugs to use with myocardial ischemia or congestive heart failure
Nitroglycerine infusion, Labetalol, Fenoldopan, and Morphine Sulfate (decrease pain)
Drugs to use for Eclampsia/pre-eclampsia
Hydralazine or Magnesium Sulfate
Prolonged usage of 48-72 hours causes renal failure and thiocyanate toxicity
Nitroprusside
Arterial and venous dilator that can cause a severe headache
Nitroglycerine
Arterial dilator recommended in pregnancy
Hydralazine
Trimethaphan
Ganglionic block
Cannot be used with any other meds except Lanoxin and Insulin
Phentolamine
Watch out with overdosing because it will cause paralysis of the diaphragm
Magnesium Sulfate
Acetazolamide
Carbonic Anhydrase Inhibitor
Dorzolamide
Carbonic Anhydrase Inhibitor
Brinzolamide
Carbonic Anhydrase Inhibitor
Methazolamide
Carbonic Anhydrase Inhibitor