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116 Cards in this Set
- Front
- Back
Triamterene
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Na+ channel blocker - prevent K+ loss
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Amiloride
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Na+ channel blocker - prevent K+ loss
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Spironolactone
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Aldosterone Receptor Antagonist - prevent K+ loss
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Eplerenone
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Aldosterone Receptor Antagonist - prevent K+ loss
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Propranolol
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Non-selective B antagonist
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Nadolol
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Non-selective B antagonist
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Timolol
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Non-selective B antagonist
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Pindolol
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Non-selective B antagonist
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Carteolol
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Non-selective B antagonist
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Levobunolol
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Non-selective B antagonist
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Metoprolol
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Selective B1 antagonist
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Atenolol
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Selective B1 antagonist
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Acebutolol
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Selective B1 antagonist
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Betaxolol
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Selective B1 antagonist
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Bisoprolol
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Selective B1 antagonist
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Esmolol
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Selective B1 antagonist
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Nebivolol
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Selective B1 antagonist at 10 mg or less; Non-selective at 10 mg or more - stimulates nitric oxide activity
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Verapamil
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Calcium Channel Blocker - Non-DHP
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Diltiazem
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Calcium Channel Blocker - Non-DHP
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Nifedipine
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Calcium Channel Blocker - DHP
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Amlodipine
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Calcium Channel Blocker - DHP
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Isradipine
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Calcium Channel Blocker - DHP
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Felodipine
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Calcium Channel Blocker - DHP
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Nisoldipine
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Calcium Channel Blocker - DHP
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Nimodipine
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Calcium Channel Blocker - DHP - Somewhat selective for cerebral arterioles - useful with subarachnoid hemorrhage
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Nicardipine
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Calcium Channel Blocker - DHP
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Clevidipine
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Calcium Channel Blocker - DHP
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Calcium Channel Blockers that act on the vasculature
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Dihydropyridines (DHP)
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Calcium Channel Blockers that act on the heart
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Verapamil and Diltiazem
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Captopril
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ACE Inhibitor
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Enalapril
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ACE Inhibitor
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Lisinopril
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ACE Inhibitor
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Ramipril
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ACE Inhibitor
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Quinapril
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ACE Inhibitor
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Fosinopril
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ACE Inhibitor
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Benazepril
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ACE Inhibitor
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Moexipril
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ACE Inhibitor
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Perindopril
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ACE Inhibitor
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Trandolapril
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ACE Inhibitor
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Mechanism of action for ACE Inhibitors
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Inhibits the production of Angiotensin II and inhibits the breakdown of bradykinin
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Captopril
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ACE Inhibitor
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Adverse effects of Captopril
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Loss of taste (metallic taste) and skin rash
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Losartan
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ARB antagonist
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Valsartan
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ARB antagonist
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Candesartan
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ARB antagonist
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Irbesartan
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ARB antagonist
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Telmisartan
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ARB antagonist
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Eprosartan
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ARB antagonist
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Olmesartan
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ARB antagonist
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Aliskiren
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Renin inhibitor
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Hydrochlorothiazide
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Thiazide Diuretics
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Chlorthalidone
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Thiazide Diuretics
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Metolazone
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Thiazide Diuretics
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Chlorothiazide
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Thiazide Diuretics
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Bendroflumethiazide
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Thiazide Diuretics
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Methyclothiazide
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Thiazide Diuretics
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Polythiazide
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Thiazide Diuretics
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Trichlormethiazide
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Thiazide Diuretics
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Furosemide
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Loop Diuretics
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Torsemide
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Loop Diuretics
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Bumetanide
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Loop Diuretics
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Ethacrynic acid
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Loop Diuretics
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K+ sparing diuretics
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Triamterene and Amiloride (Na Channel blockers); Spironolactone and Eplerenone (aldosterone antagonist)
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Diuretics to use on patient with stable angina
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B blocker and calcium channel blocker (think Non-DHP's to avoid reflex tachycardia)
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Diuretics to use on patient with acute coronary syndrome (unstable angina or myocardial infarction)
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B blocker or ACE inhibitor
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Diuretics to use on patient with postmyocardial infarction
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B blocker, ACE inhibitor, or Aldosterone antagonist
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Diuretics to use on patient with GFR <60 ml/min per 1.73m2
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ACE inhibitor or ARB
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Diuretics to use on patient with GFR <30 ml/min per 1.73m2
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Loop diuretics in combination with other drugs
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Recurrent stroke rates are lowered with a combination of these diuretics
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ACE inhibitor and Thiazide diuretic
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First line diuretics for African American patient
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Thiazide diuretic or Calcium Channel blocker
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First line diuretics for pregnancy
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Methyldopa, B-blockers, vasodilators
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Don’t use these hypertension drugs in pregnant or sexually active girls
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ARBs or ACE inhibitors (teratogenic)
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Hypertension drug to use with patient with hypertension and osteoporosis
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Thiazide diuretics
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Hypertension drug to use with patient with hypertension and atrial tachyarrhythmias/fibrillation, migraines, thyrotoxicosis, essential tremor
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B-blockers
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Hypertension drug to use with patient with hypertension and Raynaud's syndrome and certain arrhythmias
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Calcium Channel blockers
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Hypertension drug to use with patient with hypertension and prostatism
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Alpha blockers
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Hypertension drugs not to use with patients with hypertension and gout or hyponatremia
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Thiazide diuretics
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Hypertension drugs not to use with patients with hypertension and asthma or 2nd or 3rd degree heart block
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B-blockers
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Hypertension drugs not to use with patients with hypertension and likely to be pregnant
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ACE inhibitors or ARBs
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Hypertension drugs not to use with patients with hypertension and history of angioedema
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ACE inhibitors
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Hypertension drugs not to use with patients with hypertension and hyperkalemia
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Potassium sparing diuretics (aldosterone antagonists and Na Channel blockers) and ACE inhibitors
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Diabetic Patient comes in with hypertension - first line drug?
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ACE inhibitors or ARBs because of their protective kidney benefits
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Phentolamine
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Non-selective a-blocker - not used to treat essential hypertension
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Phenoxybenzamine
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Non-selective a- - not used to treat essential hypertension
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Prazosin
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Selective a1 blocker
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Terazosin
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Selective a1 blocker
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Doxazosin
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Selective a1 blocker
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Labetalol
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a and b-blocker
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Methyldopa
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Centrally acting a2 agonist - used for hypertension with pregnancy
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Clonidine
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Centrally acting a2 agonist - transdermal patch is better tolerated
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Adverse effects of methyldopa
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Positive Coombs test (common) - hemolytic anemia (rare) - hepatotoxicity
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Adverse effects of clonidine
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Rebound hypertension (can be very severe) - nervousness, tachycardia, headache and sweating
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Artery vasodilators
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Hydralazine, Minoxidil, and Fenoldopam
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Artery and vein vasodilator
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Nitroprusside
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Mechanism of action for minoxidil
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Activates K+ channels on arterial smooth muscle thus hyperpolarizing them
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Adverse effects for Hydralazine
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Lupus-like syndrome - fever, arthralgia, skin rashes
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Adverse effect for Minoxidil
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Hypertrichosis
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Mechanism of action for Fenoldopam
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Activates dopamine D1 receptors
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Mechanism of action for Nitroprusside
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Increased Nitric Oxide - increases cGMP - arterial and venous vasodilation
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Adverse effects of cyanide and thiocyanate toxicity
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Nitroprusside
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Hypertension drug that works the fastest for an Urgency/Emergency
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Nitroprusside
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Most frequent signs of a hypertension urgency
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headache, epistaxis, faintness/agitation
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Most frequent signs of a hypertension emergency
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chest pain, dyspnea, and neurological deficit
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Drugs to use for hypertensive encephalopathy, central nervous system event, or renal failure
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Labetalol, Nitroprusside, and Fenoldopan
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Drugs to use with myocardial ischemia or congestive heart failure
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Nitroglycerine infusion, Labetalol, Fenoldopan, and Morphine Sulfate (decrease pain)
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Drugs to use for Eclampsia/pre-eclampsia
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Hydralazine or Magnesium Sulfate
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Prolonged usage of 48-72 hours causes renal failure and thiocyanate toxicity
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Nitroprusside
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Arterial and venous dilator that can cause a severe headache
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Nitroglycerine
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Arterial dilator recommended in pregnancy
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Hydralazine
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Trimethaphan
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Ganglionic block
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Cannot be used with any other meds except Lanoxin and Insulin
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Phentolamine
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Watch out with overdosing because it will cause paralysis of the diaphragm
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Magnesium Sulfate
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Acetazolamide
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Carbonic Anhydrase Inhibitor
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Dorzolamide
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Carbonic Anhydrase Inhibitor
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Brinzolamide
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Carbonic Anhydrase Inhibitor
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Methazolamide
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Carbonic Anhydrase Inhibitor
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